Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Flurin Cathomas"'
Autor:
Amni Al-Kachak, Giuseppina Di Salvo, Sasha L. Fulton, Jennifer C Chan, Lorna A. Farrelly, Ashley E. Lepack, Ryan M. Bastle, Lingchun Kong, Flurin Cathomas, Emily L. Newman, Caroline Menard, Aarthi Ramakrishnan, Polina Safovich, Yang Lyu, Herbert E. Covington, Li Shen, Kelly Gleason, Carol A. Tamminga, Scott J. Russo, Ian Maze
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Mood disorders are an enigmatic class of debilitating illnesses that affect millions of individuals worldwide. While chronic stress clearly increases incidence levels of mood disorders, including major depressive disorder (MDD), stress-media
Externí odkaz:
https://doaj.org/article/b2c5b24c092e46f3a1215efcaf06b44a
Autor:
Flurin Cathomas, Laura Bevilacqua, Aarthi Ramakrishnan, Hope Kronman, Sara Costi, Molly Schneider, Kenny L. Chan, Long Li, Eric J. Nestler, Li Shen, Dennis S. Charney, Scott J. Russo, James W. Murrough
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Ketamine has rapid and sustained antidepressant effects in patients with treatment-resistant depression (TRD). However, the underlying mechanisms of action are not well understood. There is increasing evidence that TRD is associated with a p
Externí odkaz:
https://doaj.org/article/9578aab04ada4803bcc382d8a0f3d527
Autor:
Laurence Dion-Albert, Alice Cadoret, Ellen Doney, Fernanda Neutzling Kaufmann, Katarzyna A. Dudek, Beatrice Daigle, Lyonna F. Parise, Flurin Cathomas, Nalia Samba, Natalie Hudson, Manon Lebel, Signature Consortium, Matthew Campbell, Gustavo Turecki, Naguib Mechawar, Caroline Menard
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The vascular, cellular and molecular changes underlying sex differences in mood disorders are unclear. Here, the authors show that blood-brain barrier dysfunction modulates anxiety- and depressive-like behaviors in female mice and endothelium-specifi
Externí odkaz:
https://doaj.org/article/d2ef15a1a10847a7855a1f91a1dc70f2
Autor:
Sara Costi, Laurel S. Morris, Abigail Collins, Nicolas F. Fernandez, Manishkumar Patel, Hui Xie, Seunghee Kim-Schulze, Emily R. Stern, Katherine A. Collins, Flurin Cathomas, Michael K. Parides, Alexis E. Whitton, Diego A. Pizzagalli, Scott J. Russo, James W. Murrough
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Increased levels of peripheral cytokines have been previously associated with depression in preclinical and clinical research. Although the precise nature of peripheral immune dysfunction in depression remains unclear, evidence from animal s
Externí odkaz:
https://doaj.org/article/ba742c5afe7d476aa19d67c3d88c7bb5
Autor:
Federica Klaus, Karoline Guetter, Rebecca Schlegel, Tobias R. Spiller, Erich Seifritz, Flurin Cathomas, Stefan Kaiser
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Schizophrenia (SZ) and major depressive disorder (MDD) are severe mental disorders, which have been associated with alterations of the peripheral inflammatory network. However, studies for both disorders have not been fully consistent and ha
Externí odkaz:
https://doaj.org/article/53eb570a1d574be2bf3de2d2e71037f0
Autor:
Nagiua Cuomo-Haymour, Stefan Kaiser, Matthias Hartmann-Riemer, Karoline Guetter, Federica Klaus, Flurin Cathomas, Erich Seifritz, Giorgio Bergamini, Giancarlo Russo, Christopher R. Pryce
Publikováno v:
Biomarkers in Neuropsychiatry, Vol 6, Iss , Pp 100049- (2022)
Background: Major depressive disorder (MDD) presents with both peripheral and central alterations, such that crosstalk between the periphery and the central nervous system could contribute to its aetio-pathophysiology. One putative mediating mechanis
Externí odkaz:
https://doaj.org/article/63a1a9a6ac4344488f7d37423f46bf0f
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Tryptophan and its catabolites (TRYCATs) have been suggested to link peripheral immune system activation and central neurotransmitter abnormalities with relevance to the etio-pathophysiology of schizophrenia (SZ) and major depressive disorde
Externí odkaz:
https://doaj.org/article/1776a6e286cd4af58010460e1f044ff1
Autor:
Flurin Cathomas, Federica Klaus, Karoline Guetter, Hui-Kuan Chung, Anjali Raja Beharelle, Tobias R. Spiller, Rebecca Schlegel, Erich Seifritz, Matthias N. Hartmann-Riemer, Philippe N. Tobler, Stefan Kaiser
Publikováno v:
npj Schizophrenia, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract One aspect of goal-directed behavior, which is known to be impaired in patients with schizophrenia (SZ), is balancing between exploiting a familiar choice with known reward value and exploring a lesser known, but potentially more rewarding o
Externí odkaz:
https://doaj.org/article/17e18aa4117b4be7af52d1184f3009f7
Autor:
Sarah Boukezzi, Sara Costi, Lisa M. Shin, Seunghee Kim-Schulze, Flurin Cathomas, Abigail Collins, Scott J. Russo, Laurel S. Morris, James W. Murrough
Publikováno v:
Brain, Behavior, and Immunity. 104:205-212
Depression is characterized by altered neurobiological responses to threat and inflammation may be involved in the development and maintenance of symptoms. However, the mechanistic pathways underlying the relationship between the neural underpinnings
Autor:
Scott Russo, Flurin Cathomas, Hsiao-yun Lin, Kenny Chan, Long Li, Romain Durand-de Cuttoli, Lyonna Parise, Antonio Aubry, Samer Muhareb, Fiona Desland, Yusuke Shimo, Aarthi Ramakrishnan, Molly Estill, Carmen Ferrer-Perez, Eric Parise, Jun Wang, Allison Sowa, William Janssen, Sara Costi, Adeeb Rahman, Nicolas Fernandez, Filip Swirski, Eric Nestler, Li Shen, Miriam Merad, James Murrough
Psychosocial stress has profound effects on the body, including the peripheral immune system and the brain1,2. Although a large number of pre-clinical and clinical studies have linked peripheral immune system alterations to stress-related disorders s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7c4c5f4f941779901d8849faeb60f52
https://doi.org/10.21203/rs.3.rs-1647827/v1
https://doi.org/10.21203/rs.3.rs-1647827/v1