Early evaluation using a radiomic signature of unresectable hepatic metastases to predict outcome in patients with colorectal cancer treated with FOLFIRI and bevacizumab

Autor: Anthony, Dohan, Benoit, Gallix, Boris, Guiu, Karine, Le Malicot, Caroline, Reinhold, Philippe, Soyer, Jaafar, Bennouna, Francois, Ghiringhelli, Emilie, Barbier, Valérie, Boige, Julien, Taieb, Olivier, Bouché, Eric, François, Jean-Marc, Phelip, Christian, Borel, Roger, Faroux, Jean-Francois, Seitz, Stéphane, Jacquot, Meher, Ben Abdelghani, Faiza, Khemissa-Akouz, Dominique, Genet, Jean Louis, Jouve, Yves, Rinaldi, Françoise, Desseigne, Patrick, Texereau, Etienne, Suc, Come, Lepage, Thomas, Aparicio, Christine, Hoeffel, Zied, Ladhib

Publikováno v: Gut
Gut, BMJ Publishing Group, 2020, 69 (3), pp.531-539. ⟨10.1136/gutjnl-2018-316407⟩

PurposeThe objective of this study was to build and validate a radiomic signature to predict early a poor outcome using baseline and 2-month evaluation CT and to compare it to the RECIST1·1 and morphological criteria defined by changes in homogeneit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8075364a64f6848b3680bb08f7c9c30
https://doi.org/10.1136/gutjnl-2018-316407

Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: Protocol of a multicentre, open-label, parralel-group, phase II-III, randomised, superiority study (CAIRO6)

Autor: Koen P. Rovers, Checca Bakkers, Geert A. A. M. Simkens, Jacobus W. A. Burger, Simon W. Nienhuijs, Geert-Jan M. Creemers, Anna M. J. Thijs, Alexandra R. M. Brandt-Kerkhof, Eva V. E. Madsen, Ninos Ayez, Nadine L. de Boer, Esther van Meerten, Jurriaan B. Tuynman, Miranda Kusters, Nina R. Sluiter, Henk M. W. Verheul, Hans J. van der Vliet, Marinus J. Wiezer, Djamila Boerma, Emma C. E. Wassenaar, Maartje Los, Cornelis B. Hunting, Arend G. J. Aalbers, Niels F. M. Kok, Koert F. D. Kuhlmann, Henk Boot, Myriam Chalabi, Schelto Kruijff, Lukas B. Been, Robert J. van Ginkel, Derk Jan A. de Groot, Rudolf S. N. Fehrmann, Johannes H. W. de Wilt, Andreas J. A. Bremers, Philip R. de Reuver, Sandra A. Radema, Karin H. Herbschleb, Wilhelmina M. U. van Grevenstein, Arjen J. Witkamp, Miriam Koopman, Nadia Haj Mohammad, Eino B. van Duyn, Walter J. B. Mastboom, Leonie J. M. Mekenkamp, Joost Nederend, Max J. Lahaye, Petur Snaebjornsson, Cornelis Verhoef, Hanneke W. M. van Laarhoven, Aeilko H. Zwinderman, Jeanette M. Bouma, Onno Kranenburg, Iris van ‘t Erve, Remond J. A. Fijneman, Marcel G. W. Dijkgraaf, Patrick H. J. Hemmer, Cornelis J. A. Punt, Pieter J. Tanis, Ignace H. J. T. de Hingh, Dutch Peritoneal Oncology Group (DPOG), Dutch Colorectal Cancer Group (DCCG)

Publikováno v: BMC Cancer, 19
BMC cancer, 19(1):390. BioMed Central
BMC Cancer, 19(1). BioMed Central
Rovers, K P, Bakkers, C, Simkens, G A A M, Burger, J W A, Nienhuijs, S W, Creemers, G-J M, Thijs, A M J, Brandt-Kerkhof, A R M, Madsen, E V E, Ayez, N, de Boer, N L, van Meerten, E, Tuynman, J B, Kusters, M, Sluiter, N R, Verheul, H M W, van der Vliet, H J, Wiezer, M J, Boerma, D, Wassenaar, E C E, Los, M, Hunting, C B, Aalbers, A G J, Kok, N F M, Kuhlmann, K F D, Boot, H, Chalabi, M, Kruijff, S, Been, L B, van Ginkel, R J, de Groot, D J A, Fehrmann, R S N, de Wilt, J H W, Bremers, A J A, de Reuver, P R, Radema, S A, Herbschleb, K H, van Grevenstein, W M U, Witkamp, A J, Koopman, M, Haj Mohammad, N, van Duyn, E B, Mastboom, W J B, Mekenkamp, L J M, Nederend, J, Lahaye, M J, Snaebjornsson, P, Verhoef, C, van Laarhoven, H W M, Zwinderman, A H, Bouma, J M, Kranenburg, O, van 't Erve, I, Fijneman, R J A, Dijkgraaf, M G W, Hemmer, P H J, Punt, C J A, Tanis, P J & de Hingh, I H J T 2019, ' Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: Protocol of a multicentre, open-label, parralel-group, phase II-III, randomised, superiority study (CAIRO6) ', BMC Cancer, vol. 19, no. 1, 390 . https://doi.org/10.1186/s12885-019-5545-0
BMC Cancer, 19:390. BioMed Central Ltd.
BMC Cancer, 19:390. BMC
BMC Cancer, 19(1):390. BioMed Central
BMC Cancer, Vol 19, Iss 1, Pp 1-15 (2019)

Background Upfront cytoreductive surgery with HIPEC (CRS-HIPEC) is the standard treatment for isolated resectable colorectal peritoneal metastases (PM) in the Netherlands. This study investigates whether addition of perioperative systemic therapy to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410235f4855c4dd4392ec44a9e7244ce
https://doi.org/10.1186/s12885-019-5545-0

Perioperative chemotherapy for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial

Autor: Al-Batran, Salah-Eddin, Homann, Nils, Pauligk, Claudia, Goetze, Thorsten O, Meiler, Johannes, Kasper, Stefan, Kopp, Hans-Georg, Mayer, Frank, Haag, Georg Martin, Luley, Kim, Lindig, Udo, Schmiegel, Wolff, Pohl, Michael, Stoehlmacher, Jan, Folprecht, Gunnar, Probst, Stephan, Prasnikar, Nicole, Fischbach, Wolfgang, Mahlberg, Rolf, Trojan, Jörg, Koenigsmann, Michael, Martens, Uwe M, Thuss-Patience, Peter, Egger, Matthias, Block, Andreas, Heinemann, Volker, Illerhaus, Gerald, Moehler, Markus, Schenk, Michael, Kullmann, Frank, Behringer, Dirk M, Heike, Michael, Pink, Daniel, Teschendorf, Christian, Löhr, Carmen, Bernhard, Helga, Schuch, Gunter, Rethwisch, Volker, von Weikersthal, Ludwig Fischer, Hartmann, Jörg T, Kneba, Michael, Daum, Severin, Schulmann, Karsten, Weniger, Jörg, Belle, Sebastian, Gaiser, Timo, Oduncu, Fuat S, Güntner, Martina, Hozaeel, Wael, Reichart, Alexander, Jäger, Elke, Kraus, Thomas, Moenig, Stefan Paul, Bechstein, Wolf O, Schuler, Martin, Schmalenberg, Harald, Hofheinz, Ralf D, FLOT4-AIO Investigators

Publikováno v: The Lancet, Vol. 393, No 10184 (2019) pp. 1948-1957

Docetaxel-based chemotherapy is effective in metastatic gastric and gastro-oesophageal junction adenocarcinoma. This study reports on the safety and efficacy of the docetaxel-based triplet FLOT (fluorouracil plus leucovorin, oxaliplatin and docetaxel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1400::0b9cf264bfe92e55766adcd35c21e6e4
https://archive-ouverte.unige.ch/unige:134616

Chemotherapy for advanced gastric cancer

Autor: Markus Moehler, Wei Peng Yong, Jingshan Ho, Susanne Unverzagt, Wilfried Grothe, Anna Dorothea Wagner, Nicholas Syn, Bee Choo Tai

Publikováno v: The Cochrane Library
The Cochrane database of systematic reviews, vol. 8, pp. CD004064

Background Gastric cancer is the fifth most common cancer worldwide. In "Western" countries, most people are either diagnosed at an advanced stage, or develop a relapse after surgery with curative intent. In people with advanced disease, significant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d449a6958393810f646e84962d016c
https://doi.org/10.1002/14651858.cd004064.pub4

Second-line systemic therapy for metastatic colorectal cancer

Autor: Mocellin, S, Baretta, Z, Figuls, MRI, Sola, I, Martin-Richard, M, Hallum, S, Cosp, XB

Publikováno v: Cochrane Database of Systematic Reviews
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Background The therapeutic management of people with metastatic colorectal cancer (CRC) who did not respond to first-line treatment represents a formidable challenge. Objectives To determine the efficacy and toxicity of second-line systemic therapy i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::48cfe8629a75eb8a31317f73b669fcca
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=6723