Zobrazeno 1 - 10
of 4 677
pro vyhledávání: '"Fluorogenic"'
Autor:
Rabea Voget, Julian Breidenbach, Tobias Claff, Alexandra Hingst, Katharina Sylvester, Christian Steinebach, Lan Phuong Vu, Renato H. Weiße, Ulrike Bartz, Norbert Sträter, Christa E. Müller, Michael Gütschow
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 5, Pp 2349-2357 (2024)
A titrant for the SARS-CoV-2 main protease (Mpro) was developed that enables, for the first time, the exact determination of the concentration of the enzymatically active Mpro by active-site titration. The covalent binding mode of the tetrapeptidic t
Externí odkaz:
https://doaj.org/article/58da7d67bdec41a39ad53783d3a36b34
Autor:
Meng Chen, Xing Huang, Yakun Shi, Wen Wang, Zhan Huang, Yanli Tong, Xiaoyong Zou, Yuzhi Xu, Zong Dai
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract CRISPR‐based genomic‐imaging systems have been utilized for spatiotemporal imaging of the repetitive genomic loci in living cells, but they are still challenged by limited signal‐to‐noise ratio (SNR) at a non‐repetitive genomic loc
Externí odkaz:
https://doaj.org/article/f9e15cda91ea444ab1519cb9ad9aeeaf
Autor:
Yang Ding, Jingjie Chen, Qiong Wu, Bin Fang, Wenhui Ji, Xin Li, Changmin Yu, Xuchun Wang, Xiamin Cheng, Hai‐Dong Yu, Zhangjun Hu, Kajsa Uvdal, Peng Li, Lin Li, Wei Huang
Publikováno v:
SmartMat, Vol 5, Iss 3, Pp n/a-n/a (2024)
Abstract As one of the major causes of antimicrobial resistance, β‐lactamase develops rapidly among bacteria. Detection of β‐lactamase in an efficient and low‐cost point‐of‐care testing (POCT) way is urgently needed. However, due to the v
Externí odkaz:
https://doaj.org/article/fa6e82a5130542258584b4e3bffa329d
Autor:
Siyang Ding, Oana Sanislav, Daniel Missailidis, Claire Yvonne Allan, Tze Cin Owyong, Ming‐Yu Wu, Sijie Chen, Paul Robert Fisher, Sarah Jane Annesley, Yuning Hong
Publikováno v:
Advanced Sensor Research, Vol 3, Iss 6, Pp n/a-n/a (2024)
Abstract Lipid droplets (LDs) are dynamic cellular organelles that play an essential role in lipid metabolism and storage. LD dysregulation has been implicated in various diseases. However, investigations into the cellular LD dynamics under disease c
Externí odkaz:
https://doaj.org/article/0a14df331e5840fe80ea42d320c5a39a
Publikováno v:
Advanced Science, Vol 11, Iss 15, Pp n/a-n/a (2024)
Abstract In the realm of cell research, membraneless organelles have become a subject of increasing interest. However, their ever‐changing and amorphous morphological characteristics have long presented a formidable challenge when it comes to study
Externí odkaz:
https://doaj.org/article/5f4e2b5ece864432b1b6dee7c5d9cf73
Publikováno v:
Aggregate, Vol 5, Iss 2, Pp n/a-n/a (2024)
Abstract Fluorogenic biosensors are essential tools widely used in biomedicine, chemical biology, environmental protection and food safety. Fluorescence resonance energy transfer (FRET) is a crucial technique for developing fluorogenic biosensors tha
Externí odkaz:
https://doaj.org/article/a7a38f08fb2341cd95a3ce0846a3fa12
Akademický článek
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Publikováno v:
Biosensors, Vol 14, Iss 8, p 376 (2024)
Small molecules are highly relevant targets for detection and quantification. They are also used to diagnose and monitor the progression of disease and infectious processes and track the presence of contaminants. Fluorogenic RNA-based biosensors (FRB
Externí odkaz:
https://doaj.org/article/3e4775670fd64959b410cc6e52a17ba9
Shifting Mycobacterial Serine Hydrolase Activity Visualized Using Multi-Layer In-Gel Activity Assays
Publikováno v:
Molecules, Vol 29, Iss 14, p 3386 (2024)
The ability of Mycobacterium tuberculosis to derive lipids from the host, store them intracellularly, and then break them down into energy requires a battery of serine hydrolases. Serine hydrolases are a large, diverse enzyme family with functional r
Externí odkaz:
https://doaj.org/article/f24077a2b1184d5e863d6d2464797cc4
Autor:
Yanyan Chen, Tingting Hao, Jing Wang, Yiming Chen, Xiuxiu Wang, Wei Wei, Jing Zhao, Yong Qian
Publikováno v:
Advanced Science, Vol 11, Iss 2, Pp n/a-n/a (2024)
Abstract Sphingosine (Sph) plays important roles in various complex biological processes. Abnormalities in Sph metabolism can result in various diseases, including neurodegenerative disorders. However, due to the lack of rapid and accurate detection
Externí odkaz:
https://doaj.org/article/7638bb3fa65940c3b893a8f49fcfd016