Zobrazeno 1 - 10
of 18 697
pro vyhledávání: '"Fluorescence Lifetime Imaging"'
Autor:
Madison R. Pickett, Yuan-I Chen, Mohini Kamra, Sachin Kumar, Nikhith Kalkunte, Gabriella P. Sugerman, Kelsey Varodom, Manuel K. Rausch, Janet Zoldan, Hsin-Chin Yeh, Sapun H. Parekh
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract The extracellular matrix (ECM) is a dynamic and complex microenvironment that modulates cell behavior and cell fate. Changes in ECM composition and architecture have been correlated with development, differentiation, and disease progression
Externí odkaz:
https://doaj.org/article/d87cd75796ac42b7bdc9800124804eef
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Fluorescent labels have strongly contributed to many advancements in bioanalysis, molecular biology, molecular imaging, and medical diagnostics. Despite a large toolbox of molecular and nanoscale fluorophores to choose from, there is still a
Externí odkaz:
https://doaj.org/article/84b84b8dd4534131afacbf70fed67db4
Publikováno v:
Biophysica, Vol 4, Iss 2, Pp 207-226 (2024)
Drug delivery systems play a pivotal role in targeted pharmaceutical transport and controlled release at specific sites. Liposomes, commonly used as drug carriers, constitute a fundamental part of these systems. Moreover, the drug–liposome model se
Externí odkaz:
https://doaj.org/article/7ac1039f615b49658f84df96c05654a7
Insights into metabolic heterogeneity of colorectal cancer gained from fluorescence lifetime imaging
Autor:
Anastasia D Komarova, Snezhana D Sinyushkina, Ilia D Shchechkin, Irina N Druzhkova, Sofia A Smirnova, Vitaliy M Terekhov, Artem M Mozherov, Nadezhda I Ignatova, Elena E Nikonova, Evgeny A Shirshin, Liubov E Shimolina, Sergey V Gamayunov, Vladislav I Shcheslavskiy, Marina V Shirmanova
Publikováno v:
eLife, Vol 13 (2024)
Heterogeneity of tumor metabolism is an important, but still poorly understood aspect of tumor biology. Present work is focused on the visualization and quantification of cellular metabolic heterogeneity of colorectal cancer using fluorescence lifeti
Externí odkaz:
https://doaj.org/article/5e57f664a6284bd389556bc991227b0a
Autor:
Lina El Hajji, France Lam, Maria Avtodeeva, Hela Benaissa, Christine Rampon, Michel Volovitch, Sophie Vriz, Arnaud Gautier
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract Fluorescence lifetime imaging microscopy (FLIM) opens new dimensions for highly multiplexed imaging in live cells and organisms using differences in fluorescence lifetime to distinguish spectrally identical fluorescent probes. Here, a set of
Externí odkaz:
https://doaj.org/article/84e2e34863ee418b96db9902cd256659
Autor:
Jakub Nedbal, Francesco Mattioli Della Rocca, Iveta T. Ivanova, Andrew Allan, Jeremy Graham, Richard Walker, Robert K. Henderson, Klaus Suhling
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract A wide-field microscope with epi-fluorescence and selective plane illumination was combined with a single-photon avalanche diode (SPAD) array camera to enable live-cell fluorescence lifetime imaging (FLIM) using time-correlated single-photon
Externí odkaz:
https://doaj.org/article/78a058f6e46d4a32b05dfddb3c3db302
Publikováno v:
Discover Nano, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract The near-infrared (NIR) range of the electromagnetic (EM) spectrum offers a nearly transparent window for imaging tissue. Despite the significant potential of NIR fluorescence-based imaging, its establishment in basic research and clinical a
Externí odkaz:
https://doaj.org/article/85a2ddeac5f44e4eb4f1f5b5eb1be138
Autor:
Erin Su, Niranjana Kesavamoorthy, Jason A. Junge, Mengmei Zheng, Cheryl Mae Craft, Hossein Ameri
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 1, Pp 612-620 (2024)
Fluorescence lifetime imaging microscopy (FLIM) is a technique that analyzes the metabolic state of tissues based on the spatial distribution of fluorescence lifetimes of certain interacting molecules. We used multiphoton FLIM to study the metabolic
Externí odkaz:
https://doaj.org/article/444080ea954d41c8950bcd5f290e1061
Autor:
Liubov E. Shimolina, Aleksandra E. Khlynova, Vadim V. Elagin, Pavel A. Bureev, Petr S. Sherin, Marina K. Kuimova, Marina V. Shirmanova
Publikováno v:
Biomedicines, Vol 12, Iss 11, p 2550 (2024)
Background: Despite the fundamental importance of cell membrane microviscosity, changes in this biophysical parameter of membranes during photodynamic therapy (PDT) have not been fully understood. Methods: In this work, changes in the microviscosity
Externí odkaz:
https://doaj.org/article/2821404e9a4646de96336b701c0bc6b6
Autor:
Jinzheng Lu, Ling Miao, Jiaxing Wen, Qiang Li, Jingwei Chen, Qiang Yang, Xing Zhang, Jin Li, Yuchi Wu, Yue Yang, Sixin Wu, Wenbo Mo, Qiang Xiang
Publikováno v:
Photonics, Vol 11, Iss 10, p 973 (2024)
In practical applications such as cancer diagnosis and industrial detection, there is a critical demand for fast fluorescence lifetime imaging (Fast-FLIM). The Fast-FLIM systems suitable for complex environments are typically achieved by enhancing th
Externí odkaz:
https://doaj.org/article/30bba81eee17439c9ed07baf96ade855