Zobrazeno 1 - 10
of 7 426
pro vyhledávání: '"Flt3"'
Autor:
Monica Messina, Alfonso Piciocchi, Leonardo M. Siena, Stefano Soddu, Francesco Buccisano, Cristina Mecucci, Giovanni Martinelli, Antonio Curti, Roberto Cairoli, Paola Fazi, Marco Vignetti, Maria Teresa Voso, Adriano Venditti, Anna Candoni
Publikováno v:
eJHaem, Vol 5, Iss 6, Pp 1274-1277 (2024)
Abstract Given the limited data on the real‐life therapeutic use of feline McDonough sarcoma (FMS)‐like tyrosine kinase 3 (FLT3) inhibitors in Italy, we surveyed investigators at 59 Italian hematology centers to gain insight into the proportion o
Externí odkaz:
https://doaj.org/article/2fe19f632fcc4e089bc8f256326dab04
Autor:
Riyad N.H. Seervai, MD, PhD, Elena Paz Munoz, BS, S. Caleb Freeman, MD, Ronan I. Swords, MD, PhD, Kevin P. White, MD, Jesse J. Keller, MD, MCR
Publikováno v:
JAAD Case Reports, Vol 54, Iss , Pp 89-92 (2024)
Externí odkaz:
https://doaj.org/article/91867e03554c40a387d982f63a7a9036
Autor:
Ling Jiang, Yu Zhao, Fang Liu, Yun Huang, Yujiao Zhang, Baoyi Yuan, Jiaying Cheng, Ping Yan, Jinle Ni, Yongshuai Jiang, Quan Wu, Xuejie Jiang
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Approximately 25–30% of patients with acute myeloid leukemia (AML) have FMS-like receptor tyrosine kinase-3 (FLT3) mutations that contribute to disease progression and poor prognosis. Prolonged exposure to FLT3 tyrosine kinase i
Externí odkaz:
https://doaj.org/article/14b61ae9140e425ebfee0407ee01a1be
Autor:
Chuhong Hu, Yvyin Zhang, Jie Yang, Yanli Xu, Tingfen Deng, Yumiao Li, Shilin Xu, Shunqing Wang, Peihong Wang
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background FMS-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) is a common mutation type in acute myeloid leukemia (AML) and is usually associated with poor patient prognosis. With advancements in molecular diagnostics and the
Externí odkaz:
https://doaj.org/article/8009670eecd249c4ad38edcc32956240
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
Objective: Extramedullary relapse (EMR) is rare in acute promyelocytic leukemia (APL) and, there is a lack of information on its management. Current practices for EMR in APL are always to adopt strategies from other subtypes of Acute lymphoblastic le
Externí odkaz:
https://doaj.org/article/fc78f18c7ef54d06b5baf47e66b46a1d
Autor:
Noor Rashidha Binte Meera Sahib, Jameelah Sheik Mohamed, Masturah Bte Mohd Abdul Rashid, Jayalakshmi, Yihao Clement Lin, Yen Lin Chee, Bingwen Eugene Fan, Sanjay De Mel, Melissa Gaik Ming Ooi, Wei‐Ying Jen, Edward Kai‐Hua Chow
Publikováno v:
Cancer Medicine, Vol 13, Iss 22, Pp n/a-n/a (2024)
ABSTRACT Background Despite advances made in targeted biomarker‐based therapy for acute myeloid leukemia (AML) treatment, remission is often short and followed by relapse and acquired resistance. Functional precision medicine (FPM) efforts have bee
Externí odkaz:
https://doaj.org/article/24ff16d9434c4154b1fe6a23ccc4e652
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Transient Perivascular Inflammation of the\ Carotid Artery (TIPIC) syndrome is uncommon, and cases of TIPIC induced by the targeted drug, sorafenib, are extremely rare. This case report describes a patient with acute myeloid leukemia carrying an FMS
Externí odkaz:
https://doaj.org/article/8c8acb52e97e4373b3f5ff764cd39a0c
Publikováno v:
Brazilian Journal of Biology, Vol 84 (2024)
Abstract This study aimed to investigate the impact of Vernonia amygdalina leaf extract on FLT3 regulation. V. amygdalina was extracted with 96% ethanol (VAE-96), and its cytotoxicity against FLT3- cell lines (MOLM-13 and MV-4-11) was evaluated. The
Externí odkaz:
https://doaj.org/article/1a3cef1efc8e46868fc111f476b0700f
Autor:
Liu Jianwei, Gu Jianguo
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 1199-1207 (2024)
FMS-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase expressed in hematopoietic cells. Internal-tandem duplication domain (ITD) mutation and tyrosine kinase domain (TKD) mutation are the two most common mutations in acute myeloid leukemia
Externí odkaz:
https://doaj.org/article/a040752fc06f4781813d074953acfa5a
Autor:
Karam Ashouri, Krithika Chennapan, Anastasia Martynova, Samvel Nazaretyan, Amir Ali, Anush Aram Ginosyan, Eric Tam, Abdullah Ladha, Karrune Woan, Preet Chaudhary, Imran Siddiqi, George Yaghmour
Publikováno v:
eJHaem, Vol 5, Iss 2, Pp 423-427 (2024)
Externí odkaz:
https://doaj.org/article/275e3b98e2f440e8abd653b714c3971f