Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Floyd L Wormley"'
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011115 (2023)
Vaccines are one of the most effective public health tools to prevent and manage infectious diseases. Since the first clinical use of vaccines in the late 18th century, many vaccines have been successfully developed to combat bacterial and viral infe
Externí odkaz:
https://doaj.org/article/1c081750fc734c8c9524d70f2062967d
Autor:
Ujjaldeep Jaggi, Harry H Matundan, Jack Yu, Satoshi Hirose, Mathias Mueller, Floyd L Wormley, Homayon Ghiasi
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009999 (2021)
Ocular HSV-1 infection is a major cause of eye disease and innate and adaptive immunity both play a role in protection and pathology associated with ocular infection. Previously we have shown that M1-type macrophages are the major and earliest infilt
Externí odkaz:
https://doaj.org/article/fc977b80a51a4b22958b32729e59586c
Autor:
Yue Chen, Sean M Vargas, Trever C Smith, Sai Lakshmi Rajasekhar Karna, Taylor MacMackin Ingle, Karen L Wozniak, Floyd L Wormley, Janakiram Seshu
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009535 (2021)
The Peptidoglycan (PG) cell wall of the Lyme disease (LD) spirochete, Borrelia burgdorferi (Bb), contributes to structural and morphological integrity of Bb; is a persistent antigen in LD patients; and has a unique pentapeptide with L-Ornithine as th
Externí odkaz:
https://doaj.org/article/55b7520f22044c869c3544fb40f9c63c
Autor:
Chrissy M Leopold Wager, Camaron R Hole, Althea Campuzano, Natalia Castro-Lopez, Hong Cai, Marley C Caballero Van Dyke, Karen L Wozniak, Yufeng Wang, Floyd L Wormley
Publikováno v:
PLoS Pathogens, Vol 14, Iss 10, p e1007358 (2018)
Development of vaccines against opportunistic infections is difficult as patients most at risk of developing disease are deficient in aspects of the adaptive immune system. Here, we utilized an experimental immunization strategy to induce innate memo
Externí odkaz:
https://doaj.org/article/9b8f5e1d82764f04b5dcd73c9a68a8b2
Autor:
Shannon K Esher, Kyla S Ost, Maria A Kohlbrenner, Kaila M Pianalto, Calla L Telzrow, Althea Campuzano, Connie B Nichols, Carol Munro, Floyd L Wormley, J Andrew Alspaugh
Publikováno v:
PLoS Pathogens, Vol 14, Iss 6, p e1007126 (2018)
The human fungal pathogen, Cryptococcus neoformans, dramatically alters its cell wall, both in size and composition, upon entering the host. This cell wall remodeling is essential for host immune avoidance by this pathogen. In a genetic screen for mu
Externí odkaz:
https://doaj.org/article/eeac4427a615407a9b1fdb9e2afb7a60
Autor:
Althea Campuzano, Natalia Castro-Lopez, Karen L Wozniak, Chrissy M Leopold Wager, Floyd L Wormley
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169347 (2017)
C-type lectin receptors (CLRs) are diverse, trans-membrane proteins that function as pattern recognition receptors (PRRs) which are necessary for orchestrating immune responses against pathogens. CLRs have been shown to play a major role in recogniti
Externí odkaz:
https://doaj.org/article/180d81c69f9d431ca7bacb379b35e34a
Publikováno v:
PLoS Pathogens, Vol 11, Iss 6, p e1004843 (2015)
Externí odkaz:
https://doaj.org/article/ab80b89e4dbc4cf38f5c02fd57b97233
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104432 (2014)
Cryptococcus neoformans is a human fungal pathogen that causes lethal infections of the lung and central nervous system in immunocompromised individuals. C. neoformans has a defined bipolar sexual life cycle with a and α mating types. During the sex
Externí odkaz:
https://doaj.org/article/01f6063c33cc43ff8de4c2513e757b0e
Autor:
Ashok K Chaturvedi, Rumanasma S Hameed, Karen L Wozniak, Camaron R Hole, Chrissy M Leopold Wager, Susan T Weintraub, Jose L Lopez-Ribot, Floyd L Wormley
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104316 (2014)
Cryptococcus gattii is a fungal pathogen that can cause life-threatening respiratory and disseminated infections in immune-competent and immune-suppressed individuals. Currently, there are no standardized vaccines against cryptococcosis in humans, un
Externí odkaz:
https://doaj.org/article/006476fc0c804585ae736406f4ea1112
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17204 (2011)
The current studies evaluated the role of interleukin (IL)-17A in the induction of protective immunity against pulmonary cryptococcosis in mice. Protection against pulmonary infection with C. neoformans strain H99γ was associated with increased IL-1
Externí odkaz:
https://doaj.org/article/7cf16f3f8f084387b52d1b247dadf5fc