Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Floyd Averette A"'
Autor:
Thomas J C Sauters, Cullen Roth, Debra Murray, Sheng Sun, Anna Floyd Averette, Chinaemerem U Onyishi, Robin C May, Joseph Heitman, Paul M Magwene
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011763 (2023)
The "Amoeboid Predator-Fungal Animal Virulence Hypothesis" posits that interactions with environmental phagocytes shape the evolution of virulence traits in fungal pathogens. In this hypothesis, selection to avoid predation by amoeba inadvertently se
Externí odkaz:
https://doaj.org/article/2c17eb7605fa4d4c9dbdd96ee810d9cd
Autor:
Angela Rivera, Won Young Lim, Eunchong Park, Patrick A. Dome, Michael J. Hoy, Ivan Spasojevic, Sheng Sun, Anna Floyd Averette, Sergio Pina-Oviedo, Praveen R. Juvvadi, William J. Steinbach, Maria Ciofani, Jiyong Hong, Joseph Heitman
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Fungal infections are of mounting global concern, and the current limited treatment arsenal poses challenges when treating such infections. In particular, infections by Cryptococcus neoformans are associated with high mortality, emphasizing
Externí odkaz:
https://doaj.org/article/ce0b324bccb346759ee1b133f5211833
Autor:
Andrew Ryan Passer, Shelly Applen Clancey, Terrance Shea, Márcia David-Palma, Anna Floyd Averette, Teun Boekhout, Betina M Porcel, Minou Nowrousian, Christina A Cuomo, Sheng Sun, Joseph Heitman, Marco A Coelho
Publikováno v:
eLife, Vol 11 (2022)
Sexual reproduction is a ubiquitous, ancient eukaryotic trait. While most sexual organisms have to find a mating partner, species as diverse as animals, plants, and fungi have evolved the ability to reproduce sexually without requiring another indivi
Externí odkaz:
https://doaj.org/article/c4c8b2e7b5fb448f82773746fdc8c47d
Autor:
Praveen R. Juvvadi, David Fox, Benjamin G. Bobay, Michael J. Hoy, Sophie M. C. Gobeil, Ronald A. Venters, Zanetta Chang, Jackie J. Lin, Anna Floyd Averette, D. Christopher Cole, Blake C. Barrington, Joshua D. Wheaton, Maria Ciofani, Michael Trzoss, Xiaoming Li, Soo Chan Lee, Ying-Lien Chen, Mitchell Mutz, Leonard D. Spicer, Maria A. Schumacher, Joseph Heitman, William J. Steinbach
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
FK506 is a potential antifungal compound that inhibits calcineurin, but it also has immunosuppressive activity. Here, Juvvadi et al. report the structure of FK506 in complex with the FK506-binding protein FKPB12 and calcineurin, and design a less imm
Externí odkaz:
https://doaj.org/article/4b8d65315776423982c1bea6612cead9
Autor:
Andrew Ryan Passer, Marco A. Coelho, Robert Blake Billmyre, Minou Nowrousian, Moritz Mittelbach, Andrey M. Yurkov, Anna Floyd Averette, Christina A. Cuomo, Sheng Sun, Joseph Heitman
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Speciation is a central mechanism of biological diversification. While speciation is well studied in plants and animals, in comparison, relatively little is known about speciation in fungi. One fungal model is the Cryptococcus genus, which i
Externí odkaz:
https://doaj.org/article/8459708505014916bb5bcf5e7b23c32b
Autor:
Sauters, Thomas J. C., Roth, Cullen, Murray, Debra, Sun, Sheng, Floyd Averette, Anna, Onyishi, Chinaemerem U., May, Robin C., Heitman, Joseph, Magwene, Paul M.
Publikováno v:
PLoS Pathogens; 11/13/2023, Vol. 19 Issue 11, p1-28, 28p
Autor:
Thomas J. C. Sauters, Cullen Roth, Debra Murray, Sheng Sun, Anna Floyd-Averette, Chinaemerem U. Onyishi, Robin C. May, Joseph Heitman, Paul Magwene
The “Amoeboid Predator-Fungal Animal Virulence Hypothesis” posits that interactions with environmental phagocytes shape the evolution of virulence traits in fungal pathogens. In this hypothesis, selection to avoid predation by amoeba inadvertentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fea02b07876b6e564e4514289a493d17
https://doi.org/10.1101/2022.12.08.519367
https://doi.org/10.1101/2022.12.08.519367
Autor:
Eve W L Chow, Shelly A Clancey, R Blake Billmyre, Anna Floyd Averette, Joshua A Granek, Piotr Mieczkowski, Maria E Cardenas, Joseph Heitman
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006667 (2017)
Calcineurin is a highly conserved Ca2+/calmodulin-dependent serine/threonine-specific protein phosphatase that orchestrates cellular Ca2+ signaling responses. In Cryptococcus neoformans, calcineurin is activated by multiple stresses including high te
Externí odkaz:
https://doaj.org/article/dfe7e5afecf14621a9f0266cad3d30f9
Autor:
Shelly Applen Clancey, Andrew Ryan Passer, Terrance Shea, Márcia David-Palma, Anna Floyd Averette, Teun Boekhout, Betina M Porcel, Minou Nowrousian, Christina A Cuomo, Sheng Sun, Joseph Heitman, Marco A Coelho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8990ac7c507e0616be7e0443ba6ed62
https://doi.org/10.7554/elife.79114.sa2
https://doi.org/10.7554/elife.79114.sa2
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(8)
Cellular development is orchestrated by evolutionarily conserved signaling pathways, which are often pleiotropic and involve intra- and inter-pathway epistatic interactions that form intricate, complex regulatory networks. Cryptococcus species are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a957cdff5d5fcdc2a0b08e65cdd99c4
https://pubmed.ncbi.nlm.nih.gov/35503916
https://pubmed.ncbi.nlm.nih.gov/35503916