Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Floyd A. Benko"'
Publikováno v:
The Journal of Molecular Diagnostics. 16:481-485
Solid tumor genotyping has become standard of care for the characterization of proto-oncogene mutational status, which has traditionally been accomplished with Sanger sequencing. However, companion diagnostic assays and comparable laboratory-develope
Publikováno v:
Annals of the New York Academy of Sciences. 906:31-38
Publikováno v:
Annals of the New York Academy of Sciences. 945:172-178
Cancer is commonly associated with the inappropriate mRNA expression of nonmutated genes. Recently, several tumor-associated RNA species, including tyrosinase mRNA and telomerase RNA, have been demonstrated in plasma and serum. The presence of tumor
Autor:
Vincent J. Cristofalo, Maria Tresini, Robert G. Allen, Christopher D. Gocke, Glenn S. Gerhard, Anne Kalbach, Floyd A. Benko
Publikováno v:
Mechanisms of Ageing and Development. 123:155-166
Multibase deletions in mitochondrial DNA (mtDNA) have been shown to accumulate with age in several tissues, including skin, whereas point mutations have only recently been demonstrated to increase during aging, with several specific mutations occurri
Autor:
Thelma M. Watson, Elaine S. Jaffe, Barry L. Gause, Craig W. Reynolds, Robin Pennington, Carol B. Kobrin, Lars Sternas, P L Duffey, Dan L. Longo, Floyd A. Benko, Christopher D. Gocke, Maurizio Bendandi, Larry W. Kwak, Stephen P. Creekmore
Publikováno v:
Nature Medicine. 5:1171-1177
Lymphomas express a tumor-specific antigen which can be targeted by cancer vaccination. We evaluated the ability of a new idiotype protein vaccine formulation to eradicate residual t(14;18)+ lymphoma cells in 20 patients in a homogeneous, chemotherap
Publikováno v:
Human Genetics. 102:182-186
The presence of multiple mitochondrial genotypes (heteroplasmy) has been studied in normal individuals. Six multigenerational normal families were screened for heteroplasmy by PCR of the mitochondrial control region and the cytochrome c oxidase inter
Publikováno v:
The Journal of molecular diagnostics : JMD. 16(5)
Solid tumor genotyping has become standard of care for the characterization of proto-oncogene mutational status, which has traditionally been accomplished with Sanger sequencing. However, companion diagnostic assays and comparable laboratory-develope
Autor:
Christopher D. Gocke, Roger Williams, Christine A. Meece, Peter K. Rogan, Deborah A. Belchis, Floyd A. Benko
Publikováno v:
Diagnostic Molecular Pathology. 5:214-219
Studies of osteosarcoma cell lines or frozen tissue have detected loss of heterozygosity (LOH) at the retinoblastoma (RB) locus by Southern blot analysis or restriction fragment length polymorphism. Most archived clinical specimens cannot be analyzed
Publikováno v:
Annals of the New York Academy of Sciences. 906
Background A variety of tumor-related DNA has been detected in the plasma and serum of cancer patients, including RAS, the BCL2-IgH transgene, and p53. It is not known whether the APC gene, which is frequently mutated in colorectal cancer (CRC), can
Publikováno v:
Human pathology. 28(1)
Giant cell neoplasms of the pancreas are rare tumors of uncertain histogenesis. Mutation of the KRAS oncogene is common in typical pancreatic duct adenocarcinoma. We have analyzed DNA from five pancreatic tumors with giant cells for mutations in the