A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion.

Autor: Boone PG; Division of Surgical Sciences, Department of Surgery, Duke University School of Medicine, Durham, NC, USA.; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA., Rochelle LK; Division of Surgical Sciences, Department of Surgery, Duke University School of Medicine, Durham, NC, USA.; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA., Ginzel JD; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA., Lubkov V; Division of Surgical Sciences, Department of Surgery, Duke University School of Medicine, Durham, NC, USA.; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA., Roberts WL; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA., Nicholls PJ; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA., Bock C; Transgenic Mouse Facility, Duke Cancer Institute, Durham, NC, USA., Flowers ML; Transgenic Mouse Facility, Duke Cancer Institute, Durham, NC, USA., von Furstenberg RJ; Division of Gastroenterology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Stripp BR; Department of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Agarwal P; Division of Surgical Sciences, Department of Surgery, Duke University School of Medicine, Durham, NC, USA., Borowsky AD; Department of Pathology and Laboratory Medicine and The Center for Comparative Medicine, University of California-Davis, Davis, CA, USA., Cardiff RD; Department of Pathology and Laboratory Medicine and The Center for Comparative Medicine, University of California-Davis, Davis, CA, USA., Barak LS; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA., Caron MG; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA., Lyerly HK; Division of Surgical Sciences, Department of Surgery, Duke University School of Medicine, Durham, NC, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.; Department of Immunology, Duke University School of Medicine, Durham, NC, USA., Snyder JC; Division of Surgical Sciences, Department of Surgery, Duke University School of Medicine, Durham, NC, USA. joshua.snyder@duke.edu.; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA. joshua.snyder@duke.edu.

Publikováno v: Nature communications [Nat Commun] 2019 Dec 02; Vol. 10 (1), pp. 5490. Date of Electronic Publication: 2019 Dec 02.