Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Floros, VI"'
Autor:
Freyer C, Cree LM, Mourier A, Stewart JB, Koolmeister C, Milenkovic D, Wai T, Floros VI, Hagstrxf6m E, Chatzidaki EE, Wiesner RJ, Samuels DC, Larsson N.-G, Chinnery PF
Publikováno v:
Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent tra.
Autor:
Tang, WWC, Dietmann, S, Irie, N, Leitch, HG, Floros, VI, Bradshaw, CR, Hackett, JA, Chinnery, PF, Surani, MA
Publikováno v:
Cell. (6):1453-1467
SummaryResetting of the epigenome in human primordial germ cells (hPGCs) is critical for development. We show that the transcriptional program of hPGCs is distinct from that in mice, with co-expression of somatic specifiers and naive pluripotency gen
Autor:
Floros VI; MRC-Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.; Department of Clinical Neurosciences, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Pyle A; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Dietmann S; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK., Wei W; MRC-Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.; Department of Clinical Neurosciences, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Tang WWC; Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK., Irie N; Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK., Payne B; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.; Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK., Capalbo A; GENERA, Centre for Reproductive Medicine, Clinica Valle Giulia, Rome, Italy.; GENETYX, Reproductive Genetics Laboratory, Marostica, Italy., Noli L; Division of Women's Health, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Assisted Conception Unit, Guy's Hospital, London, UK., Coxhead J; Genomic Core Facility, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Hudson G; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Crosier M; Human Developmental Biology Resource, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Strahl H; Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, UK., Khalaf Y; Division of Women's Health, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Assisted Conception Unit, Guy's Hospital, London, UK., Saitou M; Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; JST, ERATO, Kyoto, Japan., Ilic D; Division of Women's Health, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Assisted Conception Unit, Guy's Hospital, London, UK., Surani MA; Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK., Chinnery PF; MRC-Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK. pfc25@cam.ac.uk.; Department of Clinical Neurosciences, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK. pfc25@cam.ac.uk.
Publikováno v:
Nature cell biology [Nat Cell Biol] 2023 Jan; Vol. 25 (1), pp. 194.
Autor:
Floros VI; MRC-Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.; Department of Clinical Neurosciences, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Pyle A; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Dietmann S; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK., Wei W; MRC-Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.; Department of Clinical Neurosciences, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Tang WWC; Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK., Irie N; Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK., Payne B; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.; Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK., Capalbo A; GENERA, Centre for Reproductive Medicine, Clinica Valle Giulia, Rome, Italy.; GENETYX, Reproductive Genetics Laboratory, Marostica, Italy., Noli L; Division of Women's Health, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Assisted Conception Unit, Guy's Hospital, London, UK., Coxhead J; Genomic Core Facility, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Hudson G; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Crosier M; Human Developmental Biology Resource, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Strahl H; Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, UK., Khalaf Y; Division of Women's Health, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Assisted Conception Unit, Guy's Hospital, London, UK., Saitou M; Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; JST, ERATO, Kyoto, Japan., Ilic D; Division of Women's Health, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Assisted Conception Unit, Guy's Hospital, London, UK., Surani MA; Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK., Chinnery PF; MRC-Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK. pfc25@cam.ac.uk.; Department of Clinical Neurosciences, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK. pfc25@cam.ac.uk.
Publikováno v:
Nature cell biology [Nat Cell Biol] 2018 Aug; Vol. 20 (8), pp. 991.
Autor:
Floros VI; MRC-Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.; Department of Clinical Neurosciences, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Pyle A; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Dietmann S; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK., Wei W; MRC-Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.; Department of Clinical Neurosciences, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Tang WCW; Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK., Irie N; Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK., Payne B; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.; Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK., Capalbo A; GENERA, Centre for Reproductive Medicine, Clinica Valle Giulia, Rome, Italy.; GENETYX, Reproductive Genetics Laboratory, Marostica, Italy., Noli L; Division of Women's Health, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Assisted Conception Unit, Guy's Hospital, London, UK., Coxhead J; Genomic Core Facility, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Hudson G; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Crosier M; Human Developmental Biology Resource, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Strahl H; Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, UK., Khalaf Y; Division of Women's Health, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Assisted Conception Unit, Guy's Hospital, London, UK., Saitou M; Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; JST, ERATO, Kyoto, Japan., Ilic D; Division of Women's Health, Faculty of Life Sciences and Medicine, King's College London, London, UK.; Assisted Conception Unit, Guy's Hospital, London, UK., Surani MA; Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK., Chinnery PF; MRC-Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK. pfc25@cam.ac.uk.; Department of Clinical Neurosciences, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK. pfc25@cam.ac.uk.
Publikováno v:
Nature cell biology [Nat Cell Biol] 2018 Feb; Vol. 20 (2), pp. 144-151. Date of Electronic Publication: 2018 Jan 15.
Autor:
Wilson IJ; Institute of Genetic Medicine., Carling PJ; Institute of Genetic Medicine, Wellcome Trust Centre for Mitochondrial Research and., Alston CL; Wellcome Trust Centre for Mitochondrial Research and Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK., Floros VI; Medical Research Council Mitochondrial Biology Unit, Cambridge, UK, Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Pyle A; Institute of Genetic Medicine, Wellcome Trust Centre for Mitochondrial Research and., Hudson G; Institute of Genetic Medicine, Wellcome Trust Centre for Mitochondrial Research and., Sallevelt SC; Department of Clinical Genetics, Research Schools GROW/CARIM, Maastricht University Medical Center, Maastricht, Netherlands., Lamperti C; Division of Molecular Neurogenetics, National Neurological Institute 'C. Besta', Milano, Italy., Carelli V; IRCCS Institute of Neurological Sciences of Bologna, Bellaria Hospital, Bologna, Italy, Unit of Neurology, Department of Biomedical and NeuroMotor Sciences (DIBINEM), University of Bologna, Bologna, Italy., Bindoff LA; Department of Neurology, Haukeland University Hospital, Bergen, Norway, Department of Clinical Medicine (K1), University of Bergen, Bergen, Norway., Samuels DC; Vanderbilt Genetics Institute, Department of Molecular Physiology and Biophysics, Vanderbilt School of Medicine, Nashville, TN, USA and., Wonnapinij P; Department of Genetics, Faculty of Science, Kasetsart University, Bangkok, Thailand., Zeviani M; Medical Research Council Mitochondrial Biology Unit, Cambridge, UK, Division of Molecular Neurogenetics, National Neurological Institute 'C. Besta', Milano, Italy., Taylor RW; Wellcome Trust Centre for Mitochondrial Research and Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK., Smeets HJ; Department of Clinical Genetics, Research Schools GROW/CARIM, Maastricht University Medical Center, Maastricht, Netherlands., Horvath R; Institute of Genetic Medicine, Wellcome Trust Centre for Mitochondrial Research and., Chinnery PF; Wellcome Trust Centre for Mitochondrial Research and Medical Research Council Mitochondrial Biology Unit, Cambridge, UK, Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK, pfc25@medschl.cam.ac.uk.
Publikováno v:
Human molecular genetics [Hum Mol Genet] 2016 Mar 01; Vol. 25 (5), pp. 1031-41. Date of Electronic Publication: 2016 Jan 05.
Autor:
Munkley J; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Oltean S; Microvascular Research Laboratories, School of Physiology and Pharmacology, University of Bristol, Bristol, UK., Vodák D; Bioinformatics Core Facility, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway., Wilson BT; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Livermore KE; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Zhou Y; Beatson Institute for Cancer Research, Glasgow, UK., Star E; Microvascular Research Laboratories, School of Physiology and Pharmacology, University of Bristol, Bristol, UK., Floros VI; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Johannessen B; Department of Molecular Oncology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway., Knight B; NIHR Exeter Clinical Research Facility, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK., McCullagh P; Department of Pathology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK., McGrath J; Exeter Surgical Health Services Research Unit, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK., Crundwell M; Department of Urology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK., Skotheim RI; Department of Molecular Oncology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway., Robson CN; Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, UK., Leung HY; Beatson Institute for Cancer Research, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Harries LW; Institute of Biomedical and Clinical Sciences, University of Exeter, Devon, UK., Rajan P; Beatson Institute for Cancer Research, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Mills IG; Prostate Cancer Research Group, Centre for Molecular Medicine Norway (NCMM), University of Oslo and Oslo University Hospitals, Oslo, Norway.; Departments of Molecular Oncology, Institute of Cancer Research and Radium Hospital, Oslo, Norway.; PCUK/Movember Centre of Excellence for Prostate Cancer Research, Centre for Cancer Research and Cell Biology (CCRCB), Queen's University, Belfast, UK., Elliott DJ; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK.
Publikováno v:
Oncotarget [Oncotarget] 2015 Oct 27; Vol. 6 (33), pp. 34358-74.
Autor:
Tang WW; Wellcome Trust Cancer Research UK Gurdon Institute, Tennis Court Road, University of Cambridge, Cambridge CB2 1QN, UK; Department of Physiology, Development and Neuroscience, Downing Street, University of Cambridge, Cambridge CB2 3EG, UK; Wellcome Trust-Medical Research Council Stem Cell Institute, Tennis Court Road, University of Cambridge, Cambridge CB2 3EG, UK., Dietmann S; Wellcome Trust-Medical Research Council Stem Cell Institute, Tennis Court Road, University of Cambridge, Cambridge CB2 3EG, UK., Irie N; Wellcome Trust Cancer Research UK Gurdon Institute, Tennis Court Road, University of Cambridge, Cambridge CB2 1QN, UK; Department of Physiology, Development and Neuroscience, Downing Street, University of Cambridge, Cambridge CB2 3EG, UK; Wellcome Trust-Medical Research Council Stem Cell Institute, Tennis Court Road, University of Cambridge, Cambridge CB2 3EG, UK., Leitch HG; Wellcome Trust-Medical Research Council Stem Cell Institute, Tennis Court Road, University of Cambridge, Cambridge CB2 3EG, UK., Floros VI; Wellcome Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK., Bradshaw CR; Wellcome Trust Cancer Research UK Gurdon Institute, Tennis Court Road, University of Cambridge, Cambridge CB2 1QN, UK., Hackett JA; Wellcome Trust Cancer Research UK Gurdon Institute, Tennis Court Road, University of Cambridge, Cambridge CB2 1QN, UK; Department of Physiology, Development and Neuroscience, Downing Street, University of Cambridge, Cambridge CB2 3EG, UK; Wellcome Trust-Medical Research Council Stem Cell Institute, Tennis Court Road, University of Cambridge, Cambridge CB2 3EG, UK., Chinnery PF; Wellcome Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK., Surani MA; Wellcome Trust Cancer Research UK Gurdon Institute, Tennis Court Road, University of Cambridge, Cambridge CB2 1QN, UK; Department of Physiology, Development and Neuroscience, Downing Street, University of Cambridge, Cambridge CB2 3EG, UK; Wellcome Trust-Medical Research Council Stem Cell Institute, Tennis Court Road, University of Cambridge, Cambridge CB2 3EG, UK. Electronic address: a.surani@gurdon.cam.ac.uk.
Publikováno v:
Cell [Cell] 2015 Jun 04; Vol. 161 (6), pp. 1453-67.
Autor:
Freyer C; Max Planck Institute for Biology of Ageing, Cologne, Germany., Cree LM, Mourier A, Stewart JB, Koolmeister C, Milenkovic D, Wai T, Floros VI, Hagström E, Chatzidaki EE, Wiesner RJ, Samuels DC, Larsson NG, Chinnery PF
Publikováno v:
Nature genetics [Nat Genet] 2012 Nov; Vol. 44 (11), pp. 1282-5. Date of Electronic Publication: 2012 Oct 07.