Elevated levels of citrullinated fibrinogen in patients with cancer

Autor: Tom Arfman, Valentina Zollet, Nick vanEs, Floris T. M. Bosch, Gerry A. F. Nicolaes, Nicoletta Sorvillo, Jan Voorberg

Publikováno v: eJHaem, Vol 5, Iss 1, Pp 136-140 (2024)

Abstract Neutrophil released peptidyl arginine deiminase 4 (PAD4) converts arginine residues on plasma proteins into citrulline. Here, we developed an assay to quantify citrullinated fibrinogen. We employed a biotin‐conjugated phenylglyoxal (biotin

Externí odkaz: https://doaj.org/article/81af964bf12e4c81afc00468102d5cf6

Direct oral anticoagulants for cancer-associated venous thromboembolism: a systematic review and meta-analysis

Autor: Marc Carrier, Floris T. M. Bosch, Annie M. Young, Tyler Zemla, Harry R. Büller, Robert D. McBane, Patrick M.M. Bossuyt, Nick van Es, Frits I. Mulder, Andrea Marshall, Jeffrey I. Weitz, Pieter Willem Kamphuisen, Saskia Middeldorp

Publikováno v: Blood. 136:1433-1441

Direct oral anticoagulants (DOACs) are an emerging treatment option for patients with cancer and acute venous thromboembolism (VTE), but studies have reported inconsistent results. This systematic review and meta-analysis compared the efficacy and sa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39db3e06a794750c64847502fda09b8c
https://doi.org/10.1182/blood.2020005819

Risk factors for gastrointestinal bleeding in patients with gastrointestinal cancer using edoxaban

Autor: Gary E. Raskob, Annelise Segers, Menno V. Huisman, Peter Verhamme, Saskia Middeldorp, Tzu-Fei Wang, Pieter Willem Kamphuisen, Floris T. M. Bosch, Jeffrey I. Zwicker, Nick van Es, David A. Garcia, Anil Duggal, Jeffrey I. Weitz, Harry R. Büller, Michael A. Grosso, Frits I. Mulder, Marc Carrier, Marcello Di Nisio

Publikováno v: Journal of thrombosis and haemostasis, 19(12), 3008-3017. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 19, 12, pp. 3008-3017
Journal of Thrombosis and Haemostasis, 19(12), 3008-3017. WILEY
Journal of Thrombosis and Haemostasis, 19, 3008-3017

BACKGROUND: In the Hokusai VTE Cancer study, the risk of major bleeding was 2.9% higher in the edoxaban group compared with the dalteparin group, mainly due to more gastrointestinal bleedings in patients with gastrointestinal cancer. The identificati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffadf52633ecf6ab6a8890f22669072
https://pure.amc.nl/en/publications/risk-factors-for-gastrointestinal-bleeding-in-patients-with-gastrointestinal-cancer-using-edoxaban(a4d44fb1-a407-4335-8fd8-c7529fc98867).html

Pulmonary embolism at autopsy in cancer patients

Autor: Harry R. Büller, Noori A.M. Guman, Floris T. M. Bosch, Pieter Willem Kamphuisen, Saskia Middeldorp, Inge A. Gimbel, Nick van Es, Jan Erik Freund, Frits I. Mulder

Publikováno v: Journal of Thrombosis and Haemostasis, 19, 1228-1235
Journal of Thrombosis and Haemostasis, 19, 5, pp. 1228-1235
Journal of thrombosis and haemostasis, 19(5), 1228-1235. Wiley-Blackwell

Contains fulltext : 245712.pdf (Publisher’s version ) (Open Access) BACKGROUND: Pulmonary embolism (PE) is a potentially fatal disease, but data on the incidence of fatal PE in cancer patients are scant. OBJECTIVE: We sought to estimate the proport

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec9235c2b6feeb8161154bc663851e9
http://hdl.handle.net/2066/245712

Primary Thromboprophylaxis in Ambulatory Cancer Patients: Where Do We Stand?

Autor: Floris T. M. Bosch, Frits I. Mulder, Nick van Es

Publikováno v: Cancers, Vol 12, Iss 2, p 367 (2020)
Cancers

Venous thromboembolism (VTE), comprising deep-vein thrombosis and pulmonary embolism, is a frequent complication in ambulatory cancer patients. Despite the high risk, routine thromboprophylaxis is not recommended because of the high number needed to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e0e70dc09ef71c748b2cc499c653de
https://www.mdpi.com/2072-6694/12/2/367