Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Floris Leenders"'
Autor:
Floris Leenders, Nathalie Groen, Natascha de Graaf, Marten A. Engelse, Ton J. Rabelink, Eelco J. P. de Koning, Françoise Carlotti
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Pancreatic β-cell failure is a critical event in the onset of both main types of diabetes mellitus but underlying mechanisms are not fully understood. β-cells have low anti-oxidant capacity, making them more susceptible to oxidative stress. In type
Externí odkaz:
https://doaj.org/article/50b393711df249ed8ab6d9d9ee96364a
Autor:
Nathalie Groen, Floris Leenders, Ahmed Mahfouz, Amadeo Munoz-Garcia, Mauro J. Muraro, Natascha de Graaf, Ton. J. Rabelink, Rob Hoeben, Alexander van Oudenaarden, Arnaud Zaldumbide, Marcel J. T. Reinders, Eelco J. P. de Koning, Françoise Carlotti
Publikováno v:
Cells, Vol 10, Iss 12, p 3585 (2021)
The maintenance of pancreatic islet architecture is crucial for proper β-cell function. We previously reported that disruption of human islet integrity could result in altered β-cell identity. Here we combine β-cell lineage tracing and single-cell
Externí odkaz:
https://doaj.org/article/f3c90ac516944d4881188fb096b01cc1
Autor:
Françoise Carlotti, Natascha de Graaf, Nathalie Groen, Marten A. Engelse, Eelco J.P. de Koning, Floris Leenders, Ton J. Rabelink
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, 12. Frontiers Media SA
Frontiers in Immunology, 12. FRONTIERS MEDIA SA
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, 12. Frontiers Media SA
Frontiers in Immunology, 12. FRONTIERS MEDIA SA
Pancreatic beta-cell failure is a critical event in the onset of both main types of diabetes mellitus but underlying mechanisms are not fully understood. beta-cells have low anti-oxidant capacity, making them more susceptible to oxidative stress. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10a0674a253e44028ca432b11a699e8
https://hdl.handle.net/1887/3276812
https://hdl.handle.net/1887/3276812
Autor:
Judith M. Bain, Mark S. Gresnigt, Xiaowen Wang, Frank L. van de Veerdonk, Lars P. Erwig, M Fernanda Alonso, Floris Leenders, Jacques F. Meis, Katharina L. Becker
Publikováno v:
Journal of Innate Immunity, 10, 2, pp. 145-U82
Journal of Innate Immunity, 10, 145-U82
Journal of Innate Immunity, 10, 145-U82
Invasive aspergillosis mainly occurs in immunocompromised patients and is commonly caused by Aspergillus fumigatus, while A.nidulans is rarely the causative agent. However, in chronic granulomatous disease (CGD) patients, A. nidulans is a frequent ca
Autor:
Janna A. van Diepen, Soohyun Kim, Philip Bufler, Michael Müller, Charles A. Dinarello, Cees J. Tack, Leo A. B. Joosten, Gert-Jan Groenhof, Eli C. Lewis, Anneke Hijmans, H.J. Jansen, Mihai G. Netea, Sander Kersten, Rinke Stienstra, Hadar Eini, Mark V. Boekschoten, Floris Leenders, Herbert Tilg, Alexander R. Moschen, Dov B. Ballak, Suzhao Li
Publikováno v:
Nature Communications. 6
Nature Communications 5: Article number: 4711 (2014); Published: 3 September 2014; Updated: 12 January 2015. The financial support for this Article was not fully acknowledged. The Acknowledgements should have read: R.S. was supported by a Ruby Grant
Autor:
Suzhao Li, Janna A. van Diepen, Hadar Eini, Cees J. Tack, Mihai G. Netea, Philip Bufler, Herbert Tilg, Anneke Hijmans, Sander Kersten, Eli C. Lewis, Mark V. Boekschoten, H.J. Jansen, Rinke Stienstra, Alexander R. Moschen, Floris Leenders, Charles A. Dinarello, Soohyun Kim, Gert-Jan Groenhof, Michael Müller, Leo A. B. Joosten, Dov B. Ballak
Publikováno v:
Nature Communications 5 (2014)
Nature Communications, 5, 4711
Nature Communications, 5
Nature Communications, 5, pp. 4711
Nature Communications, 5, 4711
Nature Communications, 5
Nature Communications, 5, pp. 4711
Contains fulltext : 138201.pdf (Publisher’s version ) (Open Access) Cytokines of the IL-1 family are important modulators of obesity-induced inflammation and the development of systemic insulin resistance. Here we show that IL-1 family member IL-37
Autor:
Leo M. A. Heunks, Marianne Linkels, Hieronymus W. H. van Hees, Jan Zoll, P. N. Richard Dekhuijzen, Willem Jan M. Schellekens, Johannes G. van der Hoeven, Floris Leenders, Rogier Donders
Publikováno v:
Critical Care
van Hees, H W H, Schellekens, W J M, Linkels, M, Leenders, F, Zoll, J, Donders, R, Dekhuijzen, P N R, van der Hoeven, J G & Heunks, L M A 2011, ' Plasma from septic shock patients induces loss of muscle protein. ', Critical care (London, England), vol. 15, no. 5 .
Critical care (London, England), 15(5). Springer Science + Business Media
van Hees, H W H, Schellekens, W J M, Linkels, M, Leenders, F, Zoll, J, Donders, R, Dekhuijzen, P N R, van der Hoeven, J G & Heunks, L M A 2011, ' Plasma from septic shock patients induces loss of muscle protein. ', Critical care (London, England), vol. 15, no. 5 .
Critical care (London, England), 15(5). Springer Science + Business Media
Introduction ICU-acquired muscle weakness commonly occurs in patients with septic shock and is associated with poor outcome. Although atrophy is known to be involved, it is unclear whether ligands in plasma from these patients are responsible for ini