Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Floris L. van Delft"'
Autor:
Marloes A. Wijdeven, Remon van Geel, Jorin H. Hoogenboom, Jorge M. M. Verkade, Brian M. G. Janssen, Inge Hurkmans, Laureen de Bever, Sander S. van Berkel, Floris L. van Delft
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Antibody-drug conjugates (ADCs) are increasingly powerful medicines for targeted cancer therapy. Inspired by the trend to further improve their therapeutic index by generation of homogenous ADCs, we report here how the clinical-stage GlycoConnect™
Externí odkaz:
https://doaj.org/article/848d309b246a42aca0115d74462db631
Autor:
Jorick J. Bruins, Criss van de Wouw, Koen Wagner, Lina Bartels, Bauke Albada, Floris L. van Delft
Publikováno v:
ACS Omega, Vol 4, Iss 7, Pp 11801-11807 (2019)
Externí odkaz:
https://doaj.org/article/e312628ee1044538a1f2877e2b32346d
Autor:
Sanne M. M. Hensen, Wilbert C. Boelens, Kimberly M. Bonger, Remco T. P. van Cruchten, Floris L. van Delft, Ger J. M. Pruijn
Publikováno v:
Molecules, Vol 20, Iss 4, Pp 6592-6600 (2015)
Citrullination is the conversion of peptidylarginine to peptidylcitrulline, which is catalyzed by peptidylarginine deiminases. This conversion is involved in different physiological processes and is associated with several diseases, including cancer
Externí odkaz:
https://doaj.org/article/1c5529670b08481997779bfbf5f10434
Autor:
Alan Rowan, Floris L. van Delft, John C. Hodges, Nancy S. Barta, Brian Gibson, Anup M. Jawalekar, Jorge M. M. Verkade, Sudip Malik
Publikováno v:
Molecules, Vol 18, Iss 7, Pp 7346-7363 (2013)
Copper-free click chemistry between cyclooctynes and azide is a mild, fast and selective technology for conjugation of oligonucleotides. However, technology for site-specific introduction of the requisite probes by automated protocols is scarce, whil
Externí odkaz:
https://doaj.org/article/fdf21aee73be4adc8f442d728c1efda9
Autor:
Jorge M. M. Verkade, Marloes A. Wijdeven, Remon van Geel, Brian M. G. Janssen, Sander S. van Berkel, Floris L. van Delft, Antibodies Editorial Office
Publikováno v:
Antibodies, Vol 7, Iss 3, p 34 (2018)
The conflict of interest section of the published paper [1] has been updated as follows[...]
Externí odkaz:
https://doaj.org/article/fb2f870787b6466e95da8a6ea1543a7a
Autor:
Floris L. van Delft, Floris P.J.T. Rutjes, Gerard W. Canters, Alessio Andreoni, Leandro C. Tabares, M. Waqar Aslam
Publikováno v:
Pharmaceuticals, Vol 3, Iss 3, Pp 679-701 (2010)
A small library of truncated neomycin-conjugates is prepared by consecutive removal of 2,6-diaminoglucose rings, oxidation-reductive amination of ribose, oxidation-conjugation of aminopyridine/aminoquinoline and finally dimerization. The dimeric conj
Externí odkaz:
https://doaj.org/article/4885a564170c4fa481e9d9cdccf86dc0
Autor:
Jorge M. M. Verkade, Marloes A. Wijdeven, Remon van Geel, Brian M. G. Janssen, Sander S. van Berkel, Floris L. van Delft
Publikováno v:
Antibodies, Vol 7, Iss 1, p 12 (2018)
Despite tremendous efforts in the field of targeted cancer therapy with antibody–drug conjugates (ADCs), attrition rates have been high. Historically, the priority in ADC development has been the selection of target, antibody, and toxin, with littl
Externí odkaz:
https://doaj.org/article/3467b0204f6846e79773a9ba2403fa4a
Autor:
Susan Roosenburg, Peter Laverman, Lieke Joosten, Annemarie Eek, Floris P.J.T. Rutjes, Floris L. van Delft, Otto C. Boerman
Publikováno v:
Molecular Imaging, Vol 11 (2012)
Cholecystokinin (CCK) receptors are overexpressed in several human tumor types, such as medullary thyroid carcinomas and small cell lung cancers. Several ligands for the CCK2 receptor (CCK2R) have been developed for radionuclide targeting of these tu
Externí odkaz:
https://doaj.org/article/e893be429ff94600bd631e0fd8ad4ecd
Autor:
Laureen de Bever, Sorraya Popal, Jord van Schaik, Baron Rubahamya, Floris L. van Delft, Greg M. Thurber, Sander S. van Berkel
Publikováno v:
Bioconjugate Chemistry. 34:538-548
Publikováno v:
Chemistry – A European Journal.