Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Floris J. van Dalen"'
Autor:
Floris J. van Dalen, Martijn Verdoes
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2566-2573 (2022)
Tumour-associated macrophages (TAMs) support tumour development and have emerged as important regulators of therapeutic response to cytostatic agents. To target TAMs, we have developed a novel drug delivery approach which induces drug release as it i
Externí odkaz:
https://doaj.org/article/247b25ee90894dc881c08194d46343dc
Autor:
Floris J. van Dalen, Thomas Bakkum, Tyrza van Leeuwen, Mirjam Groenewold, Edgar Deu, Abraham J. Koster, Sander I. van Kasteren, Martijn Verdoes
Publikováno v:
Frontiers in Chemistry, Vol 8 (2021)
Cathepsin S is a lysosomal cysteine protease highly expressed in immune cells such as dendritic cells, B cells and macrophages. Its functions include extracellular matrix breakdown and cleavage of cell adhesion molecules to facilitate immune cell mot
Externí odkaz:
https://doaj.org/article/0e57f5aafb46434b937c798381c0488d
Autor:
Floris J. van Dalen, Marleen H. M. E. van Stevendaal, Felix L. Fennemann, Martijn Verdoes, Olga Ilina
Publikováno v:
Molecules, Vol 24, Iss 1, p 9 (2018)
The tumour microenvironment (TME) is composed of extracellular matrix and non-mutated cells supporting tumour growth and development. Tumour-associated macrophages (TAMs) are among the most abundant immune cells in the TME and are responsible for the
Externí odkaz:
https://doaj.org/article/bbde0751d9804250a5e2ed630f69acad
Autor:
Kimberly M. Bonger, Camille M. Le Gall, Melek Parlak Khalily, Martijn Verdoes, Iván Ramos-Tomillero, Liyan Smeding, Carl G. Figdor, Johan M.S. van der Schoot, Anna Cammarata, Zacharias Wijfjes, Ferenc A. Scheeren, Floris J. van Dalen, Duco van Dalen
Publikováno v:
Bioconjugate Chemistry
Bioconjugate Chemistry, 32(2), 301-310. AMER CHEMICAL SOC
Bioconjugate Chemistry, 32, 2, pp. 301-310
Bioconjugate Chemistry, 32, 301-310
bioRxiv
Bioconjugate Chemistry, 32(2), 301-310. AMER CHEMICAL SOC
Bioconjugate Chemistry, 32, 2, pp. 301-310
Bioconjugate Chemistry, 32, 301-310
bioRxiv
I.AbstractFunctionalized antibodies and antibody fragments have found applications in the fields of biomedical imaging, theragnostics, and antibody-drug conjugates (ADC). Antibody functionalization is classically achieved by coupling payloads onto ly
Autor:
Nicole D. Barth, Floris J. Van Dalen, Utsa Karmakar, Marco Bertolini, Lorena Mendive‐Tapia, Takanori Kitamura, Martijn Verdoes, Marc Vendrell
Publikováno v:
Angewandte Chemie. International Edition, 61, 41
Barth, N D, Van Dalen, F J, Karmakar, U, Bertolini, M, Mendive-Tapia, L, Kitamura, T, Verdoes, M & Vendrell, M 2022, ' Enzyme-Activatable Chemokine Conjugates for In Vivo Targeting of Tumor-Associated Macrophages ', Angewandte Chemie International Edition, vol. 61, no. 41, e202207508 . https://doi.org/10.1002/anie.202207508
Angewandte Chemie. International Edition, 61
Angewandte Chemie International Edition
Barth, N D, Van Dalen, F J, Karmakar, U, Bertolini, M, Mendive-Tapia, L, Kitamura, T, Verdoes, M & Vendrell, M 2022, ' Enzyme-Activatable Chemokine Conjugates for In Vivo Targeting of Tumor-Associated Macrophages ', Angewandte Chemie International Edition, vol. 61, no. 41, e202207508 . https://doi.org/10.1002/anie.202207508
Angewandte Chemie. International Edition, 61
Angewandte Chemie International Edition
Contains fulltext : 287053.pdf (Publisher’s version ) (Open Access) Increased levels of tumor-associated macrophages (TAMs) are indicators of poor prognosis in most cancers. Although antibodies and small molecules blocking the recruitment of macrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3ec7d1ffab7bf3010140ecbdc981bb
Autor:
Sander I. van Kasteren, Thomas Bakkum, Floris J. van Dalen, Tyrza van Leeuwen, Edgar Deu, Mirjam Groenewold, Martijn Verdoes, Abraham J. Koster
Publikováno v:
Frontiers in Chemistry, 8. FRONTIERS MEDIA SA
Frontiers in Chemistry, 8, 628433
Frontiers in Chemistry, Vol 8 (2021)
Frontiers in Chemistry, 8
Frontiers in Chemistry
Thomas Bakkum
Frontiers in Chemistry, 8, 628433
Frontiers in Chemistry, Vol 8 (2021)
Frontiers in Chemistry, 8
Frontiers in Chemistry
Thomas Bakkum
Cathepsin S is a lysosomal cysteine protease highly expressed in immune cells such as dendritic cells, B cells and macrophages. Its functions include extracellular matrix breakdown and cleavage of cell adhesion molecules to facilitate immune cell mot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136c938f05f4c28d223608888eebfc33
https://doi.org/10.3389/fchem.2020.628433
https://doi.org/10.3389/fchem.2020.628433
Autor:
Martijn Verdoes, Olga Ilina, Marleen H. M. E. van Stevendaal, Felix L. Fennemann, Floris J. van Dalen
Publikováno v:
Molecules, 24, 1, pp. E9
Molecules
Molecules, Vol 24, Iss 1, p 9 (2018)
Molecules, 24, E9
Molecules
Molecules, Vol 24, Iss 1, p 9 (2018)
Molecules, 24, E9
The tumour microenvironment (TME) is composed of extracellular matrix and non-mutated cells supporting tumour growth and development. Tumour-associated macrophages (TAMs) are among the most abundant immune cells in the TME and are responsible for the