ATF4 Signaling in HIV-1 Infection: Viral Subversion of a Stress Response Transcription Factor

Autor: Adrien Corne, Florine Adolphe, Jérôme Estaquier, Sébastien Gaumer, Jean-Marc Corsi

Publikováno v: Biology, Vol 13, Iss 3, p 146 (2024)

Cellular integrated stress response (ISR), the mitochondrial unfolded protein response (UPRmt), and IFN signaling are associated with viral infections. Activating transcription factor 4 (ATF4) plays a pivotal role in these pathways and controls the e

Externí odkaz: https://doaj.org/article/ff406ca31b054679b7a6af84379a7e75

Germline mutation in the NBR1 gene involved in autophagy detected in a family with renal tumors

Autor: Katia Posseme, Sophie Giraud, Pauline Garnier, Bastien Job, Sophie Gad, Betty Gardie, Brigitte Bressac-de Paillerets, Stéphane Richard, Flore Renaud, Nathalie Droin, Virginie Verkarre, Florine Adolphe, Sophie Ferlicot, Marc Deloger, Sophie Couvé

Publikováno v: Cancer genetics.

Hereditary Renal Cell Carcinomas (RCC) are caused by mutations in predisposing genes, the major ones including VHL, FLCN, FH and MET. However, many families with inherited RCC have no germline mutation in these genes. Using Whole Exome Sequencing on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6aec633ce669f786c1605c1883229e2
https://pubmed.ncbi.nlm.nih.gov/34488032

The PHD finger protein Spp1 has distinct functions in the Set1 and the meiotic DSB formation complexes

Autor: Claire Béneut, Vérane Sommermeyer, Céline Adam, Valérie Borde, Raphael Guerois, Yohann Couté, Florine Adolphe, Anna Citarella, Laura Verardi, Jérôme Govin, Claire Ramus

Publikováno v: PLoS Genetics
PLoS Genetics, Public Library of Science, 2018, 14 (2), pp.e1007223. ⟨10.1371/journal.pgen.1007223⟩
PLoS Genetics, Public Library of Science, 2018, 14 (2), pp.e1007223. 〈10.1371/journal.pgen.1007223〉
PLoS Genetics, 2018, 14 (2), pp.e1007223. ⟨10.1371/journal.pgen.1007223⟩
PLoS Genetics, Vol 14, Iss 2, p e1007223 (2018)

Histone H3K4 methylation is a feature of meiotic recombination hotspots shared by many organisms including plants and mammals. Meiotic recombination is initiated by programmed double-strand break (DSB) formation that in budding yeast takes place in g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098f21ec9ecf78b7de0daad1eb1308d8
https://doi.org/10.1371/journal.pgen.1007223