Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Florina Borca"'
Autor:
Eleni Nastouli, Eleanor Barnes, Graham S. Cooke, Cori Campbell, Theresa Noble, David A. Smith, Steve Harris, Kinga A Várnai, Gail Roadknight, Hizni Salih, Ben Glampson, Stephanie Little, Dimitri Papadimitriou, Paul Klenerman, Luca Mercuri, Vince Taylor, Christopher R Jones, Hang Phan, Afzal Chaudhry, Josune Olza, Florina Borca, Luis Romão, Frazer Warricker, Louise English, David Ramlakhan, Monique I. Andersson, Salim I. Khakoo, Jane Collier, Philippa C. Matthews, Kerrie Woods, William Gelson, Tingyan Wang, Oliver Freeman, Jim Davies
Publikováno v:
Wellcome Open Research, Vol 7 (2023)
Background To determine the impact of the COVID-19 pandemic on the population with chronic Hepatitis B virus (HBV) infection under hospital follow-up in the UK, we quantified the coverage and frequency of measurements of biomarkers used for routine s
Externí odkaz:
https://doaj.org/article/c0516a624eaf4e1986582e7833115042
Autor:
Enrico Mossotto, Joanna Boberska, James J. Ashton, Imogen S. Stafford, Guo Cheng, Jonathan Baker, Florina Borca, Hang T. T. Phan, Tracy F. Coelho, R. Mark Beattie, Sandrine P. Claus, Sarah Ennis
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Crohn’s disease (CD) is characterised by chronic inflammation. We aimed to identify a relationship between plasma inflammatory metabolomic signature and genomic data in CD using blood plasma metabolic profiles. Proton NMR spectroscopy were
Externí odkaz:
https://doaj.org/article/99c44f320fda48c8b2bafae5f5d341cd
Autor:
Michael R Ardern-Jones, Hang T T Phan, Florina Borca, Matt Stammers, James Batchelor, Isabel C Reading, Sophie V Fletcher, Trevor Smith, Andrew S Duncombe
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280079 (2023)
BackgroundThe success of early dexamethasone therapy for hospitalised COVID-19 cases in treatment of Sars-CoV-2 infection may predominantly reflect its anti-inflammatory action against a hyperinflammation (HI) response. It is likely that there is sub
Externí odkaz:
https://doaj.org/article/c401526cf62b4996814b4e6ed5dc1641
Autor:
Ewan Carr, Rebecca Bendayan, Daniel Bean, Matt Stammers, Wenjuan Wang, Huayu Zhang, Thomas Searle, Zeljko Kraljevic, Anthony Shek, Hang T. T. Phan, Walter Muruet, Rishi K. Gupta, Anthony J. Shinton, Mike Wyatt, Ting Shi, Xin Zhang, Andrew Pickles, Daniel Stahl, Rosita Zakeri, Mahdad Noursadeghi, Kevin O’Gallagher, Matt Rogers, Amos Folarin, Andreas Karwath, Kristin E. Wickstrøm, Alvaro Köhn-Luque, Luke Slater, Victor Roth Cardoso, Christopher Bourdeaux, Aleksander Rygh Holten, Simon Ball, Chris McWilliams, Lukasz Roguski, Florina Borca, James Batchelor, Erik Koldberg Amundsen, Xiaodong Wu, Georgios V. Gkoutos, Jiaxing Sun, Ashwin Pinto, Bruce Guthrie, Cormac Breen, Abdel Douiri, Honghan Wu, Vasa Curcin, James T. Teo, Ajay M. Shah, Richard J. B. Dobson
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background The National Early Warning Score (NEWS2) is currently recommended in the UK for the risk stratification of COVID-19 patients, but little is known about its ability to detect severe cases. We aimed to evaluate NEWS2 for the predict
Externí odkaz:
https://doaj.org/article/450ca9406c4a4eb2b3e1b4b61cad19e0
Autor:
Alastair Watson, Hang Phan, Florina Borca, Sarah Williams, Tom Wilkinson, Hannah Burke, Anna Freeman, Ahilanandan Dushianthan, Michael Celinski, James Batchelor, Natasha Sheard, Paul Fitzpatrick, Dónal Landers, André Freitas, Paul O’Regan, Oskar Wysocki
Publikováno v:
BMJ Open, Vol 12, Iss 2 (2022)
Objectives COVID-19 is a heterogeneous disease, and many reports have described variations in demographic, biochemical and clinical features at presentation influencing overall hospital mortality. However, there is little information regarding longit
Externí odkaz:
https://doaj.org/article/219b6cd5397b477c8b797cbe1b594cde
Autor:
Gareth J Thomas, Saul N Faust, Christopher Kipps, Hang Phan, Florina Borca, Sarah Williams, Tom Wilkinson, Hannah Burke, Anna Freeman, Ahilanandan Dushianthan, Michael Celinski, James Batchelor, Natasha Sheard, Paul Fitzpatrick, Dónal Landers
Publikováno v:
BMJ Open, Vol 11, Iss 1 (2021)
Introduction The COVID-19 pandemic caused by SARS-CoV-2 places immense worldwide demand on healthcare services. Earlier identification of patients at risk of severe disease may allow intervention with experimental targeted treatments, mitigating the
Externí odkaz:
https://doaj.org/article/912650ad59864fc49299b66d495a79db
Autor:
Florina Borca, Martin McDonnell, Suranga Dharmasiri, Tilly Mills, Mayank Patel, Richard J Harris, Benjamin Zare, Matt Stammers, Hang T T Phan
Publikováno v:
BMJ Open Gastroenterology, Vol 7, Iss 1 (2020)
Background Glucocorticosteroids (GC) are long-established, widely used agents for induction of remission in inflammatory bowel disease (IBD). Hyperglycaemia is a known complication of GC treatment with implications for morbidity and mortality. Publis
Externí odkaz:
https://doaj.org/article/b8c49dd3b6d54fad9e8008ad8cd12fa6
Autor:
Stephen Poole, Alex R Tanner, Vasanth V Naidu, Florina Borca, Hang Phan, Kordo Saeed, Michael P W Grocott, Ahilanandan Dushianthan, Helen Moyses, Tristan W Clark
Publikováno v:
Journal of Infection. 85:625-633
Effective treatment of pneumonia requires timely administration of appropriate antimicrobials but standard diagnostic tests take around 48 h to generate results. Highly accurate, rapid molecular tests have been developed for identifying organisms in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7bb902279653c6c460ff7adcddd0d7b
https://doi.org/10.1016/j.jinf.2022.09.003
https://doi.org/10.1016/j.jinf.2022.09.003
Autor:
Matthew Stammers, Sohail Rahmany, Louise Downey, Florina Borca, Clare Harris, Richard Harris, Martin McDonnell, Stephanie Sartain, Nicolas Coleman, Bernard Stacey, Trevor R Smith, Fraser Cummings, Richard Felwick, Markus Gwiggner
Publikováno v:
Frontline Gastroenterology. 13:477-483
IntroductionPatients with suspected inflammatory bowel disease (IBD) referred from primary care often face diagnostic and treatment delays. This study aimed to compare a novel direct-access IBD endoscopy pathway with the traditional care model.Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d0cf4ea5ab9cf846deb7d99d7dde2f
https://doi.org/10.1136/flgastro-2021-102047
https://doi.org/10.1136/flgastro-2021-102047
SARS-CoV-2 viral load at presentation to hospital is independently associated with the risk of death
Autor:
Kate R Beard, Hang Phan, Florina Borca, Tristan W Clark, Nathan J Brendish, Alex R Tanner, Stephen Poole
Publikováno v:
The Journal of Infection
Objectives: Previous studies have suggested that SARS-CoV-2 viral load, measured on upper respiratory tract samples at presentation to hospital using PCR Cycle threshold (Ct) value, has prognostic utility. However, these studies have not comprehensiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b3a0455f3e7cc8b89dbeba2274bc24
https://doi.org/10.1016/j.jinf.2021.08.003
https://doi.org/10.1016/j.jinf.2021.08.003