Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Floriano Paes Silva-Junior"'
Autor:
Mario Roberto Senger, Tereza Cristina Santos Evangelista, Rafael Ferreira Dantas, Marcos Vinicius da Silva Santana, Luiz Carlos Saramago Gonçalves, Lauro Ribeiro de Souza Neto, Sabrina Baptista Ferreira, Floriano Paes Silva-Junior
Publikováno v:
Memorias do Instituto Oswaldo Cruz
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious infection that may break the healthcare system of several countries. Here, we aimed at presenting a critical view of
Externí odkaz:
https://doaj.org/article/c3f62d77fda941668bfb0952d3b1dde5
Autor:
Luiz Carlos Saramago, Marcos V. Santana, Bárbara Figueira Gomes, Rafael Ferreira Dantas, Mario R. Senger, Pedro Henrique Oliveira Borges, Vivian Neuza dos Santos Ferreira, Alice dos Santos Rosa, Amanda Resende Tucci, Milene Dias Miranda, Petra Lukacik, Claire Strain-Damerell, C. David Owen, Martin Austin Walsh, Sabrina Baptista Ferreira, Floriano Paes Silva-Junior
Publikováno v:
Journal of Chemical Information and Modeling. 63:2866-2880
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::114d1a30636294dd54b0862dee73e8de
https://doi.org/10.1021/acs.jcim.3c00409
https://doi.org/10.1021/acs.jcim.3c00409
Autor:
Lucas Villas Bôas Hoelz, Anna C. Cunha, Frederico Silva Castelo Branco, Mônica M. Bastos, Henayle Fernandes Canzian, Nubia Boechat, Andressa Paula de Oliveira, Jackson A. L. C. Resende, Luiz Claudio Ferreira Pimentel, Vinícius R. Campos, Rafael Ferreira Dantas, Floriano Paes Silva Junior
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 2260-2269 (2021)
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 2260-2269 (2021)
The enzyme tyrosine kinase BCR-Abl-1 is the main molecular target in the treatment of chronic myeloid leukemia and can be competitively inhibited by tyrosine kinase inhibitors such as imatinib. New potential competitive inhibitors were synthesized us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676ba28896d90ba5557acef9e2060dee
https://pubmed.ncbi.nlm.nih.gov/34621389
https://pubmed.ncbi.nlm.nih.gov/34621389
Autor:
Lucas Villas Bôas Hoelz, Nubia Boechat, Larissa C. Gomes, Flavia da Cunha Vasconcelos, Liviane D. de Azevedo, Mônica M. Bastos, Andressa Paula de Oliveira, Ana C. M. de Almeida, Rafael Ferreira Dantas, Floriano Paes Silva Junior, Raquel Ciuvalschi Maia
Publikováno v:
Medicinal Chemistry Research. 26:2929-2941
Imatinib was the first representative of the class of Breakpoint cluster region-Abelson murine leukemia viral oncogene homolog (BCR-ABL) tyrosine kinase inhibitors used for the treatment of chronic myeloid leukemia. Second-generation and third-genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ebf34b17a4948dbf7e36c82594da46c
https://doi.org/10.1007/s00044-017-1993-8
https://doi.org/10.1007/s00044-017-1993-8
Autor:
Paulo André Teixeira de Moraes Gomes, Marcos Veríssimo de Oliveira Cardoso, Gevanio Bezerra de Oliveira Filho, Floriano Paes Silva Junior, Regina Celia Bressan Queiroz de Figueiredo, José Wanderlan Pontes Espíndola, Lívia Bandeira Costa, Thays Gabrielle de Jesus Silva, Ana Cristina Lima Leite, Julio Martin, Pedro Henrique Monteiro Torres
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:1608-1618
Chagas disease is a tropical disease caused by the parasite Trypanosoma cruzi, which is endemic in Central and South America. Few treatments are available with effectiveness limited to the early (acute) stage of disease, significant toxicity and wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea095fda054f2b058b4ccd53082d7b86
https://doi.org/10.1016/j.bmc.2016.02.027
https://doi.org/10.1016/j.bmc.2016.02.027
Publikováno v:
Revista Virtual de Química. 11:1657-1658
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06c38ceabeb27ed0005cce25a35e68ec
https://doi.org/10.21577/1984-6835.20190116
https://doi.org/10.21577/1984-6835.20190116
This book presents the theoretical foundations of Systems Biology, as well as its application in studies on human hosts, pathogens and associated diseases. This book presents several chapters written by renowned experts in the field. Some topics dis
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 146
Phospholipases A2 (PLA2s) comprise a superfamily of glycerophospholipids hydrolyzing enzymes present in many organisms in nature, whose catalytic activity was majorly unveiled by analysis of snake venoms. The latter have pharmaceutical and biotechnol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effc02468c2c414294e15b6122519fae
https://pubmed.ncbi.nlm.nih.gov/29608922
https://pubmed.ncbi.nlm.nih.gov/29608922
Autor:
Álvaro Paiva Braga de Sousa, Bogar Omar Araujo Montoya, Nathália da Costa e Silva, Floriano Paes Silva Junior
Publikováno v:
Anais do III Simpósio Internacional de Imunobiológicos.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9840440b3ce1f49075f6a90e109eb03
https://doi.org/10.35259/isi.sact.2016_28283
https://doi.org/10.35259/isi.sact.2016_28283
Autor:
Aline R. Silveira, Fernanda Carvalho de Queiroz Mello, Raquel Lima de Figueiredo Teixeira, Pedro Hernan Cabello, Adalberto R. Santos, Afrânio Lineu Kritski, Philip Noel Suffys, Antonio Basílio de Miranda, Marcelo Fouad Rabahi, Floriano Paes Silva Junior, Leila Mendonça-Lima
Publikováno v:
Mutation research. 683(1-2)
N-Acetyltransferase 2 (NAT2) metabolizes a variety of xenobiotics that includes many drugs, chemicals and carcinogens. This enzyme is genetically variable in human populations and polymorphisms in the NAT2 gene have been associated with drug toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da57cca9019ae5c5836d11b92488ab99
https://pubmed.ncbi.nlm.nih.gov/19909761
https://pubmed.ncbi.nlm.nih.gov/19909761