Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Florianne E. Henken"'
Autor:
Renske D.M. Steenbergen, Ilse Timmerman, Mariska Bierkens, Chris J.L.M. Meijer, Renée M Overmeer, Saskia M. Wilting, Peter J.F. Snijders, Florianne E. Henken
Publikováno v:
The Journal of Pathology. 219:327-336
We recently identified MAL (T-lymphocyte maturation associated protein) as the most down-regulated gene in cervical oncogenesis. Here, we examined the mechanism underlying MAL silencing, its functional role in cervical carcinogenesis, and the relevan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e89604939c98d624e299015ed178a6a
https://doi.org/10.1002/path.2598
https://doi.org/10.1002/path.2598
Autor:
Renske D.M. Steenbergen, Saskia M. Wilting, Peter J.F. Snijders, Florianne E. Henken, Akihiko Ito, Johannes Berkhof, Daniëlle A.M. Heideman, René Overmeer, Yoshinori Murakami, Theo J.M. Helmerhorst, Chris J.L.M. Meijer, Debbie Claassen-Kramer
Publikováno v:
Journal of Pathology, 215(4), 388-397. John Wiley & Sons Ltd.
Journal of Pathology, 215(4), 388-397. John Wiley and Sons Ltd
Overmeer, R M, Henken, F E, Snijders, P J F, Claassen-Kramer, D, Berkhof, J, Helmerhorst, TJ, Heideman, D A M, Wilting, S M, Murakami, Y, Ito, A, Meijer, C J L M & Steenbergen, R D M 2008, ' Association between dense CADM1 promoter methylation and reduced protein expression in high-grade CIN and cervical SCC ', Journal of Pathology, vol. 215, no. 4, pp. 388-397 . https://doi.org/10.1002/path.2367
Journal of Pathology, 215(4), 388-397. John Wiley and Sons Ltd
Overmeer, R M, Henken, F E, Snijders, P J F, Claassen-Kramer, D, Berkhof, J, Helmerhorst, TJ, Heideman, D A M, Wilting, S M, Murakami, Y, Ito, A, Meijer, C J L M & Steenbergen, R D M 2008, ' Association between dense CADM1 promoter methylation and reduced protein expression in high-grade CIN and cervical SCC ', Journal of Pathology, vol. 215, no. 4, pp. 388-397 . https://doi.org/10.1002/path.2367
We previously showed that silencing of TSLC1 recently renamed CADM1, is functionally involved in high-risk HPV-mediated cervical carcinogenesis. CADM1 silencing often results from promoter methylation. Here, we determined the extent of CADM1 promoter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e614da7ecc809d78a02fb0bf22509fb
https://doi.org/10.1002/path.2367
https://doi.org/10.1002/path.2367
Autor:
Renske D.M. Steenbergen, Florianne E. Henken, Peter Öhlschläger, Erik Hooijberg, John B. A. G. Haanen, Leontien Bosch, Koen Oosterhuis
Publikováno v:
Vaccine, 30(28), 4259-4266. Elsevier BV
Henken, F E, Oosterhuis, K, Ohlschlager, P, Bosch, L, Hooijberg, E, Haanen, J B A G & Steenbergen, R D M 2012, ' Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7 ', Vaccine, vol. 30, no. 28, pp. 4259-4266 . https://doi.org/10.1016/j.vaccine.2012.04.013
Henken, F E, Oosterhuis, K, Ohlschlager, P, Bosch, L, Hooijberg, E, Haanen, J B A G & Steenbergen, R D M 2012, ' Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7 ', Vaccine, vol. 30, no. 28, pp. 4259-4266 . https://doi.org/10.1016/j.vaccine.2012.04.013
Persistent infection with high-risk human papillomaviruses (hrHPV) can result in the formation of anogenital cancers. As hrHPV proteins E6 and E7 are required for cancer initiation and maintenance, they are ideal targets for immunotherapeutic interve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98614e496c93452b202a38c841e0eed
https://research.vumc.nl/en/publications/8f96edf5-5cff-4293-8282-6507e62a0f7b
https://research.vumc.nl/en/publications/8f96edf5-5cff-4293-8282-6507e62a0f7b
Autor:
Thomas R. Broker, Peter J.F. Snijders, N. Sanjib Banerjee, Renske D.M. Steenbergen, Louise T. Chow, Chris J.L.M. Meijer, Frank Rösl, Florianne E. Henken, Johanna De-Castro Arce
Publikováno v:
Molecular Cancer
Molecular Cancer, 10:71. BioMed Central
Henken, F E, Banerjee, NS, Snijders, P J F, Meijer, C J L M, De-Castro Arce, J, Rosl, F, Broker, TR, Chow, L T & Steenbergen, R D M 2011, ' PIK3CA-mediated PI3-kinase signalling is essential for HPV-induced transformation in vitro ', Molecular Cancer, vol. 10, 71 . https://doi.org/10.1186/1476-4598-10-71
Molecular Cancer, Vol 10, Iss 1, p 71 (2011)
Molecular Cancer, 10:71. BioMed Central
Henken, F E, Banerjee, NS, Snijders, P J F, Meijer, C J L M, De-Castro Arce, J, Rosl, F, Broker, TR, Chow, L T & Steenbergen, R D M 2011, ' PIK3CA-mediated PI3-kinase signalling is essential for HPV-induced transformation in vitro ', Molecular Cancer, vol. 10, 71 . https://doi.org/10.1186/1476-4598-10-71
Molecular Cancer, Vol 10, Iss 1, p 71 (2011)
Background High-risk human papillomavirus (hrHPV) infections are causally related to cervical cancer development. The additional (epi)genetic alterations driving malignant transformation of hrHPV-infected cells however, are not yet fully elucidated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c76df75b66c693f0ac5c5f22639126
https://pubmed.ncbi.nlm.nih.gov/21663621
https://pubmed.ncbi.nlm.nih.gov/21663621
Autor:
Renske D.M. Steenbergen, Florianne E. Henken, Reuven Agami, Carlos le Sage, Gerrit A. Meijer, Robert A.A. van Boerdonk, Chris J.L.M. Meijer, Begoña Diosdado, Saskia M. Wilting, Peter J.F. Snijders
Publikováno v:
Wilting, S M, van Boerdonk, R A A, Henken, F E, Meijer, C J L M, Diosdado Calvo, M B, Meijer, G A, le Sage, C, Agami, R, Snijders, P J F & Steenbergen, R D M 2010, ' Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer ', Molecular Cancer, vol. 9, pp. 167 . https://doi.org/10.1186/1476-4598-9-167
Molecular Cancer, 9. BioMed Central
Molecular Cancer, Vol 9, Iss 1, p 167 (2010)
Molecular Cancer
Molecular Cancer, 9. BioMed Central
Molecular Cancer, Vol 9, Iss 1, p 167 (2010)
Molecular Cancer
Background A substantial number of microRNAs (miRNAs) is subject to epigenetic silencing in cancer. Although epigenetic silencing of tumour suppressor genes is an important feature of cervical cancer, little is known about epigenetic silencing of miR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9807e0a09498dbeb76d49c0a09b8b6f
https://research.vumc.nl/en/publications/0eed23de-5e9e-466d-aeef-c461d1f53449
https://research.vumc.nl/en/publications/0eed23de-5e9e-466d-aeef-c461d1f53449
Autor:
Renée M, Overmeer, Florianne E, Henken, Mariska, Bierkens, Saskia M, Wilting, Ilse, Timmerman, Chris J L M, Meijer, Peter J F, Snijders, Renske D M, Steenbergen
Publikováno v:
The Journal of pathology. 219(3)
We recently identified MAL (T-lymphocyte maturation associated protein) as the most down-regulated gene in cervical oncogenesis. Here, we examined the mechanism underlying MAL silencing, its functional role in cervical carcinogenesis, and the relevan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4135e9a041d4be48df8a1bd4a7136ce5
https://pubmed.ncbi.nlm.nih.gov/19662663
https://pubmed.ncbi.nlm.nih.gov/19662663
Autor:
Renée M Overmeer, Renske D.M. Steenbergen, Saskia M. Wilting, Peter J.F. Snijders, J G I van Rietschoten, A O H Nygren, Chris J.L.M. Meijer, Jan P. Schouten, A Errami, Florianne E. Henken
Publikováno v:
Henken, F E, Wilting, S M, Overmeer, R M, Van Rietschoten, J G I, Nygren, A O H, Errami, A, Schouten, J P, Meijer, C J L M, Snijders, P J F & Steenbergen, R D M 2007, ' Sequential gene promoter methylation during HPV-induced cervical carcinogenesis ', British Journal of Cancer, vol. 97, no. 10, pp. 1457-1464 . https://doi.org/10.1038/sj.bjc.6604055
British Journal of Cancer, 97(10), 1457-1464. Nature Publishing Group
British Journal of Cancer
British Journal of Cancer, 97(10), 1457-1464. Nature Publishing Group
British Journal of Cancer
We aimed to link DNA methylation events occurring in cervical carcinomas to distinct stages of HPV-induced transformation. Methylation specific-multiplex ligation-dependent probe amplification (MS-MLPA) analysis of cervical carcinomas revealed promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38feeac3053b0bc23b68cfea8a66d839
https://research.vumc.nl/en/publications/bd4685e0-1e02-4f7f-9dd2-048cafde8ba3
https://research.vumc.nl/en/publications/bd4685e0-1e02-4f7f-9dd2-048cafde8ba3
Autor:
Peter J.F. Snijders, Frank Rösl, Renske D.M. Steenbergen, Chris J.L.M. Meijer, Johanna De-Castro Arce, Florianne E. Henken, Leontien Bosch
Publikováno v:
Cellular Oncology, 35(2), 77-84. IOS Press
Henken, F E, De-Castro Arce, J, Rosl, F, Bosch, L, Meijer, C J L M, Snijders, P J F & Steenbergen, R D M 2012, ' The functional role of Notch signaling in HPV-mediated transformation is dose-dependent and linked to AP-1 alterations ', Cellular Oncology, vol. 35, no. 2, pp. 77-84 . https://doi.org/10.1007/s13402-011-0062-4
Cellular Oncology (Dordrecht)
Henken, F E, De-Castro Arce, J, Rosl, F, Bosch, L, Meijer, C J L M, Snijders, P J F & Steenbergen, R D M 2012, ' The functional role of Notch signaling in HPV-mediated transformation is dose-dependent and linked to AP-1 alterations ', Cellular Oncology, vol. 35, no. 2, pp. 77-84 . https://doi.org/10.1007/s13402-011-0062-4
Cellular Oncology (Dordrecht)
Background The role of Notch signaling in HPV-mediated transformation has been a long standing debate, as both tumor suppressive and oncogenic properties have been described. We examined whether the dual findings in literature may be explained by gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd2a58c759ec4bb0315509ee73a3927