Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Floriane Pelon"'
Autor:
Hugo Croizer, Rana Mhaidly, Yann Kieffer, Geraldine Gentric, Lounes Djerroudi, Renaud Leclere, Floriane Pelon, Catherine Robley, Mylene Bohec, Arnaud Meng, Didier Meseure, Emanuela Romano, Sylvain Baulande, Agathe Peltier, Anne Vincent-Salomon, Fatima Mechta-Grigoriou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-28 (2024)
Abstract Although heterogeneity of FAP+ Cancer-Associated Fibroblasts (CAF) has been described in breast cancer, their plasticity and spatial distribution remain poorly understood. Here, we analyze trajectory inference, deconvolute spatial transcript
Externí odkaz:
https://doaj.org/article/73b3042cd19346fdaed2121d0b1ae858
Autor:
Claire Bonneau, Antoine Eliès, Yann Kieffer, Brigitte Bourachot, Sylvain Ladoire, Floriane Pelon, Delphine Hequet, Jean-Marc Guinebretière, Christophe Blanchet, Anne Vincent-Salomon, Roman Rouzier, Fatima Mechta-Grigoriou
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-22 (2020)
Abstract Background Early luminal breast cancer (BC) represents 70% of newly diagnosed BC cases. Among them, small (under 2 cm) BC without lymph node metastasis (classified as T1N0) have been rarely studied, as their prognosis is generally favorable.
Externí odkaz:
https://doaj.org/article/7c7ee944690842e1ab659402560bb7f8
Autor:
Floriane Pelon, Brigitte Bourachot, Yann Kieffer, Ilaria Magagna, Fanny Mermet-Meillon, Isabelle Bonnet, Ana Costa, Anne-Marie Givel, Youmna Attieh, Jorge Barbazan, Claire Bonneau, Laetitia Fuhrmann, Stéphanie Descroix, Danijela Vignjevic, Pascal Silberzan, Maria Carla Parrini, Anne Vincent-Salomon, Fatima Mechta-Grigoriou
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Cancer associated fibroblasts are known to promote the progression of cancer. Here, the authors show that two particular subsets of cancer associated fibroblasts induce metastasis but work via distinct mechanisms including, chemokine signalling and N
Externí odkaz:
https://doaj.org/article/cffe5431806244e5b3bdeb1e1726578f
Autor:
Anne-Marie Givel, Yann Kieffer, Alix Scholer-Dahirel, Philemon Sirven, Melissa Cardon, Floriane Pelon, Ilaria Magagna, Géraldine Gentric, Ana Costa, Claire Bonneau, Virginie Mieulet, Anne Vincent-Salomon, Fatima Mechta-Grigoriou
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-20 (2018)
Cancer-associated fibroblasts (CAFs) are an important part of the tumor microenvironment. Here the authors characterize four subsets of CAFs across human samples of ovarian cancer subtypes and show in the mesenchymal subtype a specific CAF-S1 populat
Externí odkaz:
https://doaj.org/article/a09f89d7e4cd4d8ebd1d78403faf2e10
Autor:
Marie Nguyen, Adele De Ninno, Arianna Mencattini, Fanny Mermet-Meillon, Giulia Fornabaio, Sophia S. Evans, Mélissande Cossutta, Yasmine Khira, Weijing Han, Philémon Sirven, Floriane Pelon, Davide Di Giuseppe, Francesca Romana Bertani, Annamaria Gerardino, Ayako Yamada, Stéphanie Descroix, Vassili Soumelis, Fatima Mechta-Grigoriou, Gérard Zalcman, Jacques Camonis, Eugenio Martinelli, Luca Businaro, Maria Carla Parrini
Publikováno v:
Cell Reports, Vol 25, Iss 13, Pp 3884-3893.e3 (2018)
Summary: A major challenge in cancer research is the complexity of the tumor microenvironment, which includes the host immunological setting. Inspired by the emerging technology of organ-on-chip, we achieved 3D co-cultures in microfluidic devices (in
Externí odkaz:
https://doaj.org/article/1348722c708442c9936e214684b50064
Autor:
Fatima Mechta-Grigoriou, Anne Vincent-Salomon, Gerard Zalcman, Sylvain Baulande, Andrei Zinovyev, Karin Tarte, Alice Guyard, Claire Bonneau, Luca Albergante, Sonia Lameiras, Brigitte Bourachot, Charles Bernard, Floriane Pelon, Géraldine Gentric, Hocine R. Hocine, Yann Kieffer
Supplementary Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ed504966b5d2bebf5cc072640d4671
https://doi.org/10.1158/2159-8290.22535248.v1
https://doi.org/10.1158/2159-8290.22535248.v1
Autor:
Fatima Mechta-Grigoriou, Anne Vincent-Salomon, Gerard Zalcman, Sylvain Baulande, Andrei Zinovyev, Karin Tarte, Alice Guyard, Claire Bonneau, Luca Albergante, Sonia Lameiras, Brigitte Bourachot, Charles Bernard, Floriane Pelon, Géraldine Gentric, Hocine R. Hocine, Yann Kieffer
A subset of cancer-associated fibroblasts (FAP+/CAF-S1) mediates immunosuppression in breast cancers, but its heterogeneity and its impact on immunotherapy response remain unknown. Here, we identify 8 CAF-S1 clusters by analyzing more than 19,000 sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49654609a36d2101c83309e1d3d7eec8
https://doi.org/10.1158/2159-8290.c.6547801.v1
https://doi.org/10.1158/2159-8290.c.6547801.v1
Autor:
Fatima Mechta-Grigoriou, Anne Vincent-Salomon, Gerard Zalcman, Sylvain Baulande, Andrei Zinovyev, Karin Tarte, Alice Guyard, Claire Bonneau, Luca Albergante, Sonia Lameiras, Brigitte Bourachot, Charles Bernard, Floriane Pelon, Géraldine Gentric, Hocine R. Hocine, Yann Kieffer
Data S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0730beee17daf5c6214242535afbe427
https://doi.org/10.1158/2159-8290.22535251
https://doi.org/10.1158/2159-8290.22535251
Autor:
Yann Kieffer, Fatima Mechta-Grigoriou, Jean Marc Guinebretière, Roman Rouzier, Delphine Hequet, Floriane Pelon, Sylvain Ladoire, Christophe Blanchet, Anne Vincent-Salomon, Antoine Elies, Claire Bonneau, Brigitte Bourachot
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-22 (2020)
Breast Cancer Research
Breast Cancer Research, BioMed Central, 2020, 22 (1), ⟨10.1186/s13058-020-01311-9⟩
Breast Cancer Research : BCR
Breast Cancer Research
Breast Cancer Research, BioMed Central, 2020, 22 (1), ⟨10.1186/s13058-020-01311-9⟩
Breast Cancer Research : BCR
BackgroundEarly luminal breast cancer (BC) represents 70% of newly diagnosed BC cases. Among them, small (under 2 cm) BC without lymph node metastasis (classified as T1N0) have been rarely studied, as their prognosis is generally favorable. Neverthel
Autor:
Fatima Mechta-Grigoriou, Yann Kieffer, Anne-Marie Givel, Maria Carla Parrini, Anne Vincent-Salomon, Stéphanie Descroix, Pascal Silberzan, Claire Bonneau, Isabelle Bonnet, Laetitia Fuhrmann, Ana Catarina Costa, Ilaria Magagna, Floriane Pelon, Brigitte Bourachot, Danijela Matic Vignjevic, Jorge Barbazan, Youmna Attieh, Fanny Mermet-Meillon
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Nature Communications
Nature Communications, Nature Publishing Group, 2020, ⟨10.1038/s41467-019-14134-w⟩
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-019-14134-w⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2020, ⟨10.1038/s41467-019-14134-w⟩
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-019-14134-w⟩
Although fibroblast heterogeneity is recognized in primary tumors, both its characterization in and its impact on metastases remain unknown. Here, combining flow cytometry, immunohistochemistry and RNA-sequencing on breast cancer samples, we identify