Zobrazeno 1 - 10 of 47 pro vyhledávání: '"Floriana Bulić"'
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Akademický článek
Global DNA methylation and chondrogenesis of rat limb buds in a three-dimensional organ culture system
Autor: Vedrana Mužić Radović, Paula Bunoza, Tihana Marić, Marta Himelreich-Perić, Floriana Bulić-Jakuš, Marta Takahashi, Gordana Jurić-Lekić, Nino Sinčić, Davor Ježek, Ana Katušić-Bojanac
Publikováno v: Biomolecules & Biomedicine, Vol 22, Iss 4 (2022)
Although DNA methylation epigenetically regulates development, data on global DNA methylation during development of limb buds (LBs) are scarce. We aimed to investigate the global DNA methylation developmental dynamics in rat LBs cultivated in a serum
Externí odkaz: https://doaj.org/article/ca93b71f8acb4b7f94f5a5f459f8032c
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2
Valproate Targets Mammalian Gastrulation Impairing Neural Tissue Differentiation and Development of the Placental Source In Vitro
Autor: Ana Katušić-Bojanac, Milvija Plazibat, Marta Himelreich-Perić, Katarina Eck-Raković, Jure Krasić, Nino Sinčić, Gordana Jurić-Lekić, Davor Ježek, Floriana Bulić-Jakuš
Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 8861
The teratogenic activity of valproate (VPA), an antiepileptic and an inhibitor of histone deacetylase (HDACi), is dose-dependent in humans. Previous results showed that VPA impairs in vitro development and neural differentiation of the gastrulating e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94172e33185d6c105d2d22ab302ee8b
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3
Transmembranous and enchondral osteogenesis in transplants of rat limb buds cultivated in serum‐ and protein‐free culture medium
Autor: Marta Himelreich Perić, Vedrana Mužić‐Radović, Tihana Marić, Floriana Bulić‐Jakuš, Gordana Jurić‐Lekić, Marta Takahashi, Nino Sinčić, Davor Ježek, Ana Katušić‐Bojanac
Cartilage differentiates in rat limb buds cultivated in a chemically defined protein-free medium in the same manner as in the richer serum- supplemented medium. We aimed to investigate the remaining differentiation potential of pre- cultivated limb b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7299d8c1706db3d5958a221aa38b9a8
https://doi.org/10.1111/ahe.12835
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5
In Search of TGCT Biomarkers: A Comprehensive In Silico and Histopathological Analysis
Autor: Dora Raos, Marijana Ćorić, Floriana Bulić-Jakuš, Silvija Mašić, Bozo Kruslin, Davor Jezek, Monika Ulamec, Jure Krasic, Irena Abramovic, Ana Katušić Bojanac, Nino Sinčić
Publikováno v: Disease Markers, Vol 2020 (2020)
Testicular germ cell tumors (TGCTs) are ever more affecting the young male population. Germ cell neoplasia in situ (GCNIS) is the origin of TGCTs, namely, seminomas (SE) and a heterogeneous group of nonseminomas (NS) comprising embryonal carcinoma, t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9420115a78907a3ee7beab98779a78
https://doi.org/10.1155/2020/8841880
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6
Extended Prophylactic Effect of N-tert-Butyl-α-phenylnitron against Oxidative/Nitrosative Damage Caused by the DNA-Hypomethylating Drug 5-Azacytidine in the Rat Placenta
Autor: Nikola Sobočan, Marta Himelreich-Perić, Ana Katušić-Bojanac, Jure Krasić, Nino Sinčić, Željka Majić, Gordana Jurić-Lekić, Ljiljana Šerman, Andreja Marić, Davor Ježek, Floriana Bulić-Jakuš
Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 603
International Journal of Molecular Sciences, Vol 23, Iss 603, p 603 (2022)
International Journal of Molecular Sciences
Antioxidant N-tert-Butyl-α-phenylnitron (PBN) partly protected embryos from the negative effects of a DNA demethylating drug 5-azacytidine during pregnancy. Our aim was to investigate PBN’s impact on the placenta. Fischer rat dams were treated on
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fdb5992b1798da16989b4cf40783133
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7
MiR-182-5p and miR-375-3p Have Higher Performance Than PSA in Discriminating Prostate Cancer from Benign Prostate Hyperplasia
Autor: Tomislav Kuliš, Goran Štimac, Monika Ulamec, Floriana Bulić-Jakuš, Dejan Ljiljak, Zeljko Kastelan, Nora Nikolac Gabaj, Nino Sinčić, Lucija Škara, Irena Abramovic, Ana Katusic-Bojanac, Alen Vrtaric, Boris Ruzic, Bozo Kruslin, Borna Vrhovec
Publikováno v: Cancers, Vol 13, Iss 2068, p 2068 (2021)
Cancers
Volume 13
Issue 9
Prostate cancer (PCa) is the most commonly diagnosed neoplasm among men. Since it often resembles benign prostate hyperplasia (BPH), biomarkers with a higher differential value than PSA are required. Epigenetic biomarkers in liquid biopsies, especial
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2898d862a6cb4511d8b29a799e254634
https://doi.org/10.3390/cancers13092068
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8
Teratoma Growth Retardation by HDACi Treatment of the Tumor Embryonal Source
Autor: Sanja Dabelić, Monika Ulamec, Lucija Škara, Floriana Bulić-Jakuš, Davor Jezek, Jure Krasic, Nino Sinčić, Ana Katušić Bojanac
Publikováno v: Cancers
Cancers, Vol 12, Iss 3416, p 3416 (2020)
Volume 12
Issue 11
Simple Summary Testicular germ cell tumors are the most common neoplasms in young male populations, with a rising incidence. Among them, teratomas may often be very aggressive and resistant to therapy. Our aim was to investigate the impact of two pot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3029bf206aa6f1f8d45eabfc2d4438bf
http://europepmc.org/articles/PMC7698704
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9
Embryo-derived teratoma in vitro biological system reveals antitumor and embryotoxic activity of valproate
Autor: Mario Rašić, Ozren Gamulin, Jure Krasic, Nino Sinčić, Vedran Radonić, Floriana Bulić-Jakuš, Maria Krajačić, Marta Himerleich Perić, Gordana Jurić-Lekić, Maja Balarin, Ana Katušić Bojanac, Milvija Plazibat, Marko Škrabić
Publikováno v: The Febs Journal
Antiepileptic/teratogen valproate (VPA) is a histone deacetylase inhibitor/epigenetic drug proposed for the antitumor therapy where it is generally crucial to target poorly or undifferentiated cells to prevent a recurrence. Transplanted rodent gastru
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ade048c29521d6f9c4923c5bd41b7e2
https://www.bib.irb.hr/1057756
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10
Epigenetic drug 5-azacytidine impairs the potential for odontogenesis but improves tooth morphogenesis in the transplanted embryonic mandible
Autor: Ana Katušić Bojana, Floriana Bulić-Jakuš, Nino Sinčić, Gordana Jurić-Lekić, Marta Himelreich-Perić, Davor Ježek, Vedran Radujković, Marta Takahashi
Publikováno v: Periodicum biologorum
Volume 121-122
Issue 1-2
Background and purpose: Epigenetic mechanisms are crucial in regulating development. The aim of the study was to investigate whether a DNA-demethylation drug 5-azacytidine (5azaC) affects odontogenesis in embryonic mandibles ectopically transplanted
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a26c4c7b9486881486a0640d501dcfd4
https://hrcak.srce.hr/254650
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