Combined Brain-Perfusion SPECT and EEG Measurements Suggest Distinct Strategies for Speech Comprehension in CI Users With Higher and Lower Performance

Autor: Mariella Kessler, Irina Schierholz, Martin Mamach, Florian Wilke, Anja Hahne, Andreas Büchner, Lilli Geworski, Frank M. Bengel, Pascale Sandmann, Georg Berding

Publikováno v: Frontiers in Neuroscience, Vol 14 (2020)

Cochlear implantation constitutes a successful therapy of inner ear deafness, with the majority of patients showing good outcomes. There is, however, still some unexplained variability in outcomes with a number of cochlear-implant (CI) users, showing

Externí odkaz: https://doaj.org/article/9950c30871144468963353e79d02592a

Visualization of the auditory pathway in rats with 18F-FDG PET activation studies based on different auditory stimuli and reference conditions including cochlea ablation.

Autor: Martin Mamach, Mariella Kessler, Jens P Bankstahl, Florian Wilke, Lilli Geworski, Frank M Bengel, Simone Kurt, Georg Berding

Publikováno v: PLoS ONE, Vol 13, Iss 10, p e0205044 (2018)

Activation studies with positron emission tomography (PET) in auditory implant users explained some of the mechanisms underlying the variability of achieved speech comprehension. Since future developments of auditory implants will include studies in

Externí odkaz: https://doaj.org/article/0b991bd0510f4948a451c6d35ebcdf1b

Reliable quantification of 18F-GE-180 PET neuroinflammation studies using an individually scaled population-based input function or late tissue-to-blood ratio

Autor: Frank M. Bengel, Christian Schütze, András Polyák, Mariella Kessler, Georg Berding, Christian H. Wetzel, Linda Hamann, Ralph Buchert, Henning Pflugrad, Mario Lukacevic, Carlotta Petrusch, Tobias L. Ross, Rainer Rupprecht, Florian Wilke, Meike Dirks, Laura B. N. Langer, Martin Mamach, Ann-Katrin Wirries, Lilli Geworski, Karin Weissenborn

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging

Purpose Tracer kinetic modeling of tissue time activity curves and the individual input function based on arterial blood sampling and metabolite correction is the gold standard for quantitative characterization of microglia activation by PET with the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9609ae4a790dc96511cebaa065c94a5f
http://europepmc.org/articles/PMC7651670

Author Correction: Serotonin transporter binding is increased in Tourette syndrome with Obsessive Compulsive Disorder

Autor: Georg Berding, Kirsten R. Müller-Vahl, Lilli Geworski, Ewgeni Jakubovski, Florian Wilke, Frank M. Bengel, N. Szejko

Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-2 (2020)

While the importance of the serotonergic system in obsessive compulsive disorder (OCD) is well established, its role in Tourette syndrome (TS) is uncertain. Particularly in TS patients with comorbid OCD (TS + OCD), decreased serotonin transporter (SE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef08f7ea6bcd1fb73ddfc3dd62d352b2
http://europepmc.org/articles/PMC7326929

Cerebral microglia activation in hepatitis C virus infection correlates to cognitive dysfunction

Autor: Ronald Boellaard, Karin Weissenborn, Georg Berding, Annemarie Goldbecker, Hans Worthmann, Anita B. Tryc, Geerd Meyer, Peter Raab, Henning Pflugrad, Maqsood Yaqub, Florian Wilke, Meike Dirks

Publikováno v: Journal of Viral Hepatitis, 23(5), 348-357
Pflugrad, H, Meyer, G-J, Dirks, M, Raab, P, Tryc, A B, Goldbecker, A, Worthmann, H, Wilke, F, Boellaard, R, Yaqub, M, Berding, G & Weissenborn, K 2016, ' Cerebral microglia activation in hepatitis C virus infection correlates to cognitive dysfunction ', Journal of Viral Hepatitis, vol. 23, no. 5, pp. 348-357 . https://doi.org/10.1111/jvh.12496

Hepatitis C virus (HCV) infection may induce chronic fatigue and cognitive dysfunction. Virus replication was proven within the brain and HCV-positive cells were identified as microglia and astrocytes. We hypothesized that cerebral dysfunction in HCV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a788cf1bd1f39bff17e684b332691e0
https://doi.org/10.1111/jvh.12496