Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Florian Weissmann"'
Autor:
Jana Neuhold, Katharina Radakovics, Anita Lehner, Florian Weissmann, Maria Queralt Garcia, Mari Carmen Romero, Nicholas S. Berrow, Peggy Stolt-Bergner
Publikováno v:
BMC Biotechnology, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background Recombinant protein production and purification of large protein complexes in eukaryotes requires efficient methods to generate multi-gene expression constructs, where each individual gene is under the control of its own promoter
Externí odkaz:
https://doaj.org/article/2a6ec979be764c5d8a30b24ef358dfde
The COMA complex interacts with Cse4 and positions Sli15/Ipl1 at the budding yeast inner kinetochore
Autor:
Josef Fischböck-Halwachs, Sylvia Singh, Mia Potocnjak, Götz Hagemann, Victor Solis-Mezarino, Stephan Woike, Medini Ghodgaonkar-Steger, Florian Weissmann, Laura D Gallego, Julie Rojas, Jessica Andreani, Alwin Köhler, Franz Herzog
Publikováno v:
eLife, Vol 8 (2019)
Kinetochores are macromolecular protein complexes at centromeres that ensure accurate chromosome segregation by attaching chromosomes to spindle microtubules and integrating safeguard mechanisms. The inner kinetochore is assembled on CENP-A nucleosom
Externí odkaz:
https://doaj.org/article/6423f43976744fdfbe3bc82be536f785
Autor:
Pim J Huis in 't Veld, Sadasivam Jeganathan, Arsen Petrovic, Priyanka Singh, Juliane John, Veronica Krenn, Florian Weissmann, Tanja Bange, Andrea Musacchio
Publikováno v:
eLife, Vol 5 (2016)
Stable kinetochore-microtubule attachment is essential for cell division. It requires recruitment of outer kinetochore microtubule binders by centromere proteins C and T (CENP-C and CENP-T). To study the molecular requirements of kinetochore formatio
Externí odkaz:
https://doaj.org/article/70874f8776e94a5ba44ca6d90035ae4b
Autor:
Berta Canal, Allison W. McClure, Joseph F. Curran, Mary Wu, Rachel Ulferts, Florian Weissmann, Jingkun Zeng, Agustina P. Bertolin, Jennifer C. Milligan, Souradeep Basu, Lucy S. Drury, Tom Deegan, Ryo Fujisawa, Emma L. Roberts, Clovis Basier, Karim Labib, Rupert Beale, Michael Howell, John F.X Diffley
Publikováno v:
Biochemical Journal
SummarySARS-CoV-2 is a coronavirus that emerged in 2019 and rapidly spread across the world causing a deadly pandemic with tremendous social and economic costs. Healthcare systems worldwide are under great pressure, and there is urgent need for effec
Autor:
Kang Wei Tan, Emma L. Roberts, Tiffany Mak, Lucy S. Drury, Souradeep Basu, Berta Canal, Michael Howell, Joseph F. Curran, Florian Weissmann, Karim Labib, Tom D Deegan, John F.X. Diffley, Allison W McClure, Ryo Fujisawa, Mary Wu, Victoria H. Cowling, Rachel Ulferts, Clovis Basier, Rupert Beale, Theresa U. Zeisner, Chew Theng Lim
Publikováno v:
Biochemical Journal
The COVID-19 pandemic has presented itself as one of the most critical public health challenges of the century, with SARS-CoV-2 being the third member of the Coronaviridae family to cause a fatal disease in humans. There is currently only one antivir
Autor:
Chew Theng Lim, Kang Wei Tan, Mary Wu, Rachel Ulferts, Lee A. Armstrong, Eiko Ozono, Lucy S. Drury, Jennifer C. Milligan, Theresa U. Zeisner, Jingkun Zeng, Florian Weissmann, Berta Canal, Ganka Bineva-Todd, Michael Howell, Nicola O'Reilly, Rupert Beale, Yogesh Kulathu, Karim Labib, John F.X. Diffley
Publikováno v:
Biochemical Journal
The COVID-19 pandemic has emerged as the biggest life-threatening disease of this century. Whilst vaccination should provide a long-term solution, this is pitted against the constant threat of mutations in the virus rendering the current vaccines les
Autor:
Morgan E. Gibbs, Katarzyna M. Kedziora, J. Wade Harper, Jan-Michael Peters, Nicholas G. Brown, Florian Weissmann, Michael J. Emanuele, Raquel C. Martinez-Chacin, Gavin D. Grant, Renping Qiao, Tatyana Bodrug, Jeanette Gowen Cook, Alban Ordureau, Derek L. Bolhuis, Thomas Bonacci
Publikováno v:
Nature structural & molecular biology
The interplay between E2 and E3 enzymes regulates the polyubiquitination of substrates in eukaryotes. Among the several RING-domain E3 ligases in humans, many utilize two distinct E2s for polyubiquitination. For example, the cell cycle regulatory E3,
Autor:
Florian Weissmann, Berta Canal, Rachel Ulferts, Mary Wu, Michael Howell, John F.X. Diffley, Lucy S. Drury, Jennifer C. Milligan, Rupert Beale, Jingkun Zeng, Agustina P Bertolin, Viktor Posse
Publikováno v:
Biochemical Journal
SummaryThe coronavirus disease 2019 (COVID-19) global pandemic has turned into the largest public health and economic crisis in recent history impacting virtually all sectors of society. There is a need for effective therapeutics to battle the ongoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e349d752e1f3eb65b7e78de708e1dc8d
https://doi.org/10.1101/2021.04.07.438807
https://doi.org/10.1101/2021.04.07.438807
Autor:
Mary Wu, Clovis Basier, George Papageorgiou, Michael Howell, Christelle Soudy, Theresa U. Zeisner, Rachel Ulferts, John F.X. Diffley, Chew Theng Lim, Dhira Joshi, Joseph F. Curran, Florian Weissmann, Hema Nagaraj, Tom D Deegan, Ryo Fujisawa, Berta Canal, Karim Labib, Kang Wei Tan, Ganka Bineva-Todd, Jennifer C. Milligan, Rupert Beale
The coronavirus 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread around the world with unprecedented health and socio-economic effects for the global population. While different vaccines are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9335764f2cf6ed64e157d65e251c782
https://doi.org/10.1101/2021.04.07.438804
https://doi.org/10.1101/2021.04.07.438804
Autor:
John W. McCauley, Ruth Harvey, Mary Wu, Laura E. McCoy, Agustina P Bertolin, Viktor Posse, Rupert Beale, Lucy S. Drury, John F.X. Diffley, Svend Kjaer, Saira Hussain, Berta Canal, Annabel Borg, Florian Weissmann, Jingkun Zeng, Jennifer C. Milligan, Rachel Ulferts, Michael Howell, Chloe Roustan
Publikováno v:
Biochemical Journal
SummaryThe coronavirus disease 2019 (COVID-19) pandemic, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global public health challenge. While the efficacy of vaccines against emerging and future virus variants re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2be294aa30a2fa0bdf7de7e17f9f7f6
https://doi.org/10.1101/2021.04.07.438808
https://doi.org/10.1101/2021.04.07.438808