Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Florian T. Nickel"'
Autor:
Kilian Fröhlich, Klemens Winder, Manuel Schmidt, De-Hyung Lee, Arnd Dörfler, Ruihao Wang, Max J. Hilz, Tobias Bobinger, Florian T. Nickel, Ralf A. Linker, Frank Seifert
Publikováno v:
Neurourology and Urodynamics. 39:295-302
Aims Besides spinal lesions, urinary incontinence may be attributed to particular cerebral lesion sites in multiple sclerosis (MS) patients. We intended to determine the contribution of suprapontine lesions to urinary incontinence in MS using a voxel
Autor:
Wolf A Lagrèze, Sebastian Küchlin, Gabriele Ihorst, Birgit Grotejohann, Flemming Beisse, Martin Volkmann, Sven P Heinrich, Philipp Albrecht, Judith Ungewiss, Michael Wörner, Martin J Hug, Sebastian Wolf, Ricarda Diem, Orhan Aktas, Anna Beck, Anke Beckmann, Achim Berthele, Lena Bönig, Heike Elflein, Dirk Fitzner, Vinzenz Fleischer, Stefan Gingele, Tanja Guthoff, Rainer Guthoff, Kathrin Hartmann, Andrea Hassenstein, Christoph Heesen, Katharina Hein, Sven P. Heinrich, Karsten Hufendiek, Martin J. Hug, Konstantin Huhn, Martin W. Hümmert, Matthias Klopfer, Friedrich E. Kruse, Tania Kümpfel, Wolf A. Lagrèze, Ralf A. Linker, Katrin Lorenz, Fanni E. Molnár, Elisabeth Mulazzani, Marcus Müller, Florian T. Nickel, Marion Noll, Amelie Pielen, Susanne Pitz, Sebastian Rauer, Michael Reich, Sina Rosenkranz, Philipp Schwenkenbecher, Nelly Siller, Thomas Skripuletz, Martin Stangel, Jan-Patrick Stellmann, Klarissa Stürner, Kurt-Wolfram Sühs, Timo Uphaus, Christian van Oterendorp, Bettina Wabbels, Helmut Wilhelm, Ulf Ziemann, Frauke Zipp
Publikováno v:
The Lancet. Neurology. 20(12)
Summary Background The human cytokine erythropoietin conveys neuroprotection in animal models but has shown ambiguous results in phase 2 clinical trials in patients with optic neuritis. We assessed the safety and efficacy of erythropoietin in patient
Autor:
Yvonne K Schulz, Michael Erdmann, Lucie Heinzerling, Florian T Nickel, Elias A T Koch, Carola Berking
Publikováno v:
Journal of immunotherapy (Hagerstown, Md. : 1997). 44(3)
Checkpoint inhibitors (CPI), such as anti-programmed death-1 and anti-cytotoxic T-lymphocyte antigen-4antibodies cause serious, rarely fatal immune-related adverse events (irAE) potentially in all organ systems. Neurological immune-related adverse ev
Autor:
Julia Seybold, Kathrin S. Utz, De-Hyung Lee, Florian T. Nickel, Pauline Terhoeven, Ralf A. Linker
Publikováno v:
Journal of the neurological sciences. 419
Intravenous immunoglobulins (IVIg) represent an established cornerstone for the immunotherapy of chronic inflammatory demyelinating polyneuropathy (CIDP). Efficacy of IVIg for CIDP was proven in a large phase III trial. Yet, data on longer-term effic
Autor:
Ralf A. Linker, Konstantin Huhn, De-Hyung Lee, Victoria Prockl, Florian T. Nickel, Tobias Engelhorn, Max-Josef Hilz, Kathrin S. Utz, Kilian Fröhlich
Publikováno v:
Journal of the neurological sciences. 415
Background Pivotal trials showed good clinical efficiency of the monoclonal antibody ocrelizumab while being well tolerated and manageable in multiple sclerosis (MS). However, data on adverse events in everyday practice are scarce. Hence, our study a
Autor:
Simon Rieß, Stephan Ott, Christian Maihöfner, Wolfgang Koppert, Florian T. Nickel, Jörg Filitz, Susanne Möhringer, Tino Münster
Publikováno v:
Pain Practice. 16:820-830
Objective After surgical procedures, anesthesia itself may affect pain perception. Particularly, there is increasing evidence that opioids not only have analgesic effects but also provoke pronociceptive changes, that is, opioid-induced hyperalgesia.
Publikováno v:
Pain Practice. 16:712-719
Objective Trigeminal and cervical afferents converge on neurons of the trigeminocervical complex and may significantly alter the function of these neurons. This interaction may have implications for the pathophysiology and treatment of primary headac
Autor:
Arnd Dörfler, S. Möhringer, Frank Seifert, Marc Saake, Sabine Ott, Florian T. Nickel, Christian Maihöfner
Publikováno v:
European Journal of Pain. 18:56-66
Background Habituation to repetitive noxious stimuli is a well-known phenomenon. We investigated brain correlates of habituation to pain in a transdermal electrical pain model using functional magnetic resonance imaging (fMRI). Methods Electrical pai
Autor:
Florian T. Nickel, Frank Seifert, Elena Peltz, Christian Maihöfner, Roberto De Col, Nadine Schuberth
Publikováno v:
Hum Brain Mapp
Pain is a multidimensional phenomenon with sensory, affective, and autonomic components. Here, we used parametric functional magnetic resonance imaging (fMRI) to correlate regional brain activity with autonomic responses to (i) painful stimuli and to
Publikováno v:
European Neuropsychopharmacology. 22:81-91
Neuropathic pain is a disease of global burden. Its symptoms include spontaneous and stimulus-evoked painful sensations. Several maladaptive mechanisms underlying these symptoms have been elucidated in recent years: peripheral sensitization of nocice