Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Florian Sure"'
Autor:
Florian Sure, Marko Bertog, Sara Afonso, Alexei Diakov, Ralf Rinke, M. Gregor Madej, Sabine Wittmann, Thomas Gramberg, Christoph Korbmacher, Alexandr V. Ilyaskin
The epithelial sodium channel (ENaC) is a heterotrimer consisting of α-, β-, and γ-subunits. Channel activation requires proteolytic release of inhibitory tracts from the extracellular domains of α-ENaC and γ-ENaC; however, the proteases involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1647ad897ede0e49595e59a2dbc68df
https://epub.uni-regensburg.de/52234/
https://epub.uni-regensburg.de/52234/
Autor:
Silke Haerteis, Christoph Korbmacher, Viatcheslav Nesterov, Alexandr V. Ilyaskin, Florian Sure
Publikováno v:
The Journal of General Physiology
The human purinergic receptor P2X4 is an ATP-gated nonselective cation channel expressed in a variety of cells, including hepatocytes and cholangiocytes. Ilyaskin et al. find that the bile acids inhibit P2X4 by stabilizing the channel's closed state,
Autor:
Ferruh Artunc, Bernhard N. Bohnert, Jonas C. Schneider, Tobias Staudner, Florian Sure, Alexandr V. Ilyaskin, Matthias Wörn, Daniel Essigke, Andrea Janessa, Nis V. Nielsen, Andreas L. Birkenfeld, Michael Etscheid, Silke Haerteis, Christoph Korbmacher, Sandip M. Kanse
Publikováno v:
Pflügers Archiv, 2022(474):217-229
Pflugers Archiv
Pflugers Arch. 474, 217-229 (2022)
Pflugers Archiv
Pflugers Arch. 474, 217-229 (2022)
Proteolytic activation of the epithelial sodium channel (ENaC) by aberrantly filtered serine proteases is thought to contribute to renal sodium retention in nephrotic syndrome. However, the identity of the responsible proteases remains elusive. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45650f55637d2b812841cb6d95a7372
https://repository.publisso.de/resource/frl:6431670
https://repository.publisso.de/resource/frl:6431670
Autor:
Martina Menacher, Christoph Daniel, Kerstin Amann, Bernhard N. Bohnert, Matthias Wörn, Ferruh Artunc, Sophie Daiminger, Andrea Janessa, Hans-Ulrich Häring, Hubert Kalbacher, Florian Sure, Christoph Korbmacher, Anja Schork, Marko Bertog, Silke Haerteis
Publikováno v:
Kidney Int. 93, 159-172 (2017)
Volume retention in nephrotic syndrome has been linked to activation of the epithelial sodium channel (ENaC) by proteolysis of its γ-subunit following urinary excretion of serine proteases such as plasmin. Here we tested whether pharmacological inhi