Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Florian Stengel"'
Autor:
Rebekka Lambrecht, Jasmin Jansen, Franziska Rudolf, Mohamed El-Mesery, Sabrina Caporali, Ivano Amelio, Florian Stengel, Thomas Brunner
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-11 (2024)
Abstract Cell death is a fundamental process in health and disease. Emerging research shows the existence of numerous distinct cell death modalities with similar and intertwined signaling pathways, but resulting in different cellular outcomes, raisin
Externí odkaz:
https://doaj.org/article/3a9d112a7fe24ce3b7e658370f83dc81
Autor:
Niccolò Mosesso, Niharika Savant Lerner, Tobias Bläske, Felix Groh, Shane Maguire, Marie Laura Niedermeier, Eliane Landwehr, Karin Vogel, Konstanze Meergans, Marie-Kristin Nagel, Malte Drescher, Florian Stengel, Karin Hauser, Erika Isono
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Autophagy is relevant for diverse processes in eukaryotic cells, making its regulation of fundamental importance. The formation and maturation of autophagosomes require a complex choreography of numerous factors. The endosomal sorting comple
Externí odkaz:
https://doaj.org/article/acc1afb476b74f8ba81b36323c4b875f
Autor:
Eiji Obayashi, Rafael E. Luna, Takashi Nagata, Pilar Martin-Marcos, Hiroyuki Hiraishi, Chingakham Ranjit Singh, Jan Peter Erzberger, Fan Zhang, Haribabu Arthanari, Jacob Morris, Riccardo Pellarin, Chelsea Moore, Ian Harmon, Evangelos Papadopoulos, Hisashi Yoshida, Mahmoud L. Nasr, Satoru Unzai, Bryttney Thompson, Eric Aube, Samantha Hustak, Florian Stengel, Eddie Dagraca, Asokan Ananbandam, Philip Gao, Takeshi Urano, Alan G. Hinnebusch, Gerhard Wagner, Katsura Asano
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114404- (2024)
Externí odkaz:
https://doaj.org/article/0abf4580bb9d47ceb45f9407f4e57f48
Autor:
Thibault R. Bongiovanni, Casey J. Latario, Youn Le Cras, Evan Trus, Sophie Robitaille, Kerry Swartz, Danica Schmidtke, Maxence Vincent, Artemis Kosta, Jan Orth, Florian Stengel, Riccardo Pellarin, Eduardo P. C. Rocha, Benjamin D. Ross, Eric Durand
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The type VI secretion system (T6SS) of Gram-negative bacteria inhibits competitor cells through contact-dependent translocation of toxic effector proteins. In Proteobacteria, the T6SS is anchored to the cell envelope through a megadalton-siz
Externí odkaz:
https://doaj.org/article/2322a7da5bcf4770b7fbe860aac6d7f8
Autor:
Benedikt Goretzki, Christoph Wiedemann, Brett A. McCray, Stefan L. Schäfer, Jasmin Jansen, Frederike Tebbe, Sarah-Ana Mitrovic, Julia Nöth, Ainara Claveras Cabezudo, Jack K. Donohue, Cy M. Jeffries, Wieland Steinchen, Florian Stengel, Charlotte J. Sumner, Gerhard Hummer, Ute A. Hellmich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Intrinsically disordered regions (IDRs) are essential for membrane receptor regulation but often remain unresolved in structural studies. TRPV4, a member of the TRP vanilloid channel family involved in thermo- and osmosensation, has a large
Externí odkaz:
https://doaj.org/article/164d0c141a984b619e153ae313a859dd
Autor:
Yizhi Yuan, Florian M. Stumpf, Lisa A. Schlor, Olivia P. Schmidt, Philip Saumer, Luisa B. Huber, Matthias Frese, Eva Höllmüller, Martin Scheffner, Florian Stengel, Kay Diederichs, Andreas Marx
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
RNA ligases are present across all forms of life. Here, the hitherto uncharacterised human protein C12orf29 was identified as a human enzyme promoting RNA ligation between 5′-PO4 and 3′-OH termini. This data provides the groundwork for establishi
Externí odkaz:
https://doaj.org/article/b4697e732f064db69887d55cb4ab9c94
Autor:
Simon Maria Kienle, Tobias Schneider, Katrin Stuber, Christoph Globisch, Jasmin Jansen, Florian Stengel, Christine Peter, Andreas Marx, Michael Kovermann, Martin Scheffner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Ubiquitin is not only a posttranslational modifier but itself is subject to modifications, such as acetylation. Characterization of distinct acetylated ubiquitin variants reveals that each acetylation site has a particular impact on ubiquitin structu
Externí odkaz:
https://doaj.org/article/1e21cc4548474d48816030ee2117176a
Autor:
Lena Krüger, Christoph J. Albrecht, Hannah K. Schammann, Florian M. Stumpf, Marie L. Niedermeier, Yizhi Yuan, Katrin Stuber, Josua Wimmer, Florian Stengel, Martin Scheffner, Andreas Marx
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Diadenosine polyphosphates (ApAs) are involved in cellular stress signaling but only a few molecular targets have been characterized so far. Here, the authors develop Ap n A-based photoaffinity-labeling probes and use them to identify Ap3A and Ap4A b
Externí odkaz:
https://doaj.org/article/4eb1898661044a6890c551d0a05b51d3
Autor:
Eva Höllmüller, Simon Geigges, Marie L. Niedermeier, Kai-Michael Kammer, Simon M. Kienle, Daniel Rösner, Martin Scheffner, Andreas Marx, Florian Stengel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
While the role of specific posttranslational modifications (PTMs) is increasingly well understood for core histones, this is not the case for linker histone H1. Here the authors show that site-specific ubiquitylation of H1 results in distinct interac
Externí odkaz:
https://doaj.org/article/17bd88aa7fda430bbade73ff65e2a471
Autor:
Carolin Sailer, Jasmin Jansen, Kamil Sekulski, Victor E. Cruz, Jan P. Erzberger, Florian Stengel
Publikováno v:
Cell Reports, Vol 38, Iss 6, Pp 110353- (2022)
Summary: Eukaryotic ribosome biogenesis is facilitated and regulated by numerous ribosome biogenesis factors (RBFs). High-resolution cryoelectron microscopy (cryo-EM) maps have defined the molecular interactions of RBFs during maturation, but many tr
Externí odkaz:
https://doaj.org/article/26f8ca74ad9340298955aadc5d369c4e