Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Florian Seufert"'
Autor:
Fernando Vieira Contreras, Genevieve M. Auger, Lena Müller, Vincent Richter, Wolf Huetteroth, Florian Seufert, Peter W. Hildebrand, Nicole Scholz, Andreas S. Thum, Dmitrij Ljaschenko, Beatriz Blanco-Redondo, Tobias Langenhan
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113640- (2024)
Summary: Adhesion G-protein-coupled receptors (aGPCRs) form a large family of cell surface molecules with versatile tasks in organ development. Many aGPCRs still await their functional and pharmacological deorphanization. Here, we characterized the o
Externí odkaz:
https://doaj.org/article/6b0d071b2da64c7ca6015f86548323a1
Autor:
Peter Schmidt, Alexander Vogel, Benedikt Schwarze, Florian Seufert, Kai Licha, Virginia Wycisk, Wolfgang Kilian, Peter W. Hildebrand, Lorenz Mitschang
Publikováno v:
Molecules, Vol 28, Iss 3, p 1424 (2023)
G protein-coupled receptors can adopt many different conformational states, each of them exhibiting different restraints towards downstream signaling pathways. One promising strategy to identify and quantify this conformational landscape is to introd
Externí odkaz:
https://doaj.org/article/99fa325558b44e53847b339827fea496
Publikováno v:
Molecules, Vol 17, Iss 12, Pp 14685-14699 (2012)
The well-known Ugi reaction of aldehydes with amines, carboxylic acids and isocyanides leads to the formation of acyclic α-acylaminocarboxamides. Replacement of the carboxylic acid derivatives with β-acyl substituted acrylic acids gives access to h
Externí odkaz:
https://doaj.org/article/aa04e6decc134a8fb9f204a15e426748
Autor:
Michelle Philipp, Christopher W. Moth, Nikola Ristic, Johanna K.S. Tiemann, Florian Seufert, Jens Meiler, Peter W. Hildebrand, Amelie Stein, Daniel Wiegreffe, René Staritzbichler
The possible effects of mutations on stability and function of a protein can only be understood in the context of protein 3D structure. The MutationExplorerwebserver maps variants onto protein structures and allows users to study variation by inputti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ab78a954a24d19c336ea4da23a21aa5
https://doi.org/10.1101/2023.03.23.533926
https://doi.org/10.1101/2023.03.23.533926
Autor:
Fabian Pohl, Florian Seufert, Yin Kwan Chung, Daniela Volke, Ralf Hoffmann, Torsten Schöneberg, Tobias Langenhan, Peter W. Hildebrand, Norbert Sträter
The GAIN domain is a hallmark of adhesion G-protein coupled receptors (aGPCRs) as this extracellular domain contains an integral agonistic sequence (Stachel) for activation via binding to the 7-transmembrane helical (7TM) domain of the receptor. Many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91e6d2b47cc6d170664ab04db56c92d0
https://doi.org/10.1101/2023.03.12.532270
https://doi.org/10.1101/2023.03.12.532270
Autor:
Nicolas Julian Scheuplein, Theresa Lohr, Mirella Vivoli Vega, Dyan Ankrett, Florian Seufert, Lukas Kirchner, Nicholas J. Harmer, Ulrike Holzgrabe
Publikováno v:
SLAS Discovery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3763941f45bbd85ed2b573be3e2352b8
https://doi.org/10.1016/j.slasd.2023.03.004
https://doi.org/10.1016/j.slasd.2023.03.004
Autor:
Jua Iwasaki, Donald D. Lorimer, Mirella Vivoli-Vega, Emily A. Kibble, Christopher S. Peacock, Jan Abendroth, Stephen J. Mayclin, David M. Dranow, Phillip G. Pierce, David Fox, Maria Lewis, Nicole M. Bzdyl, Sofie S. Kristensen, Timothy J. J. Inglis, Charlene M. Kahler, Charles S. Bond, Anja Hasenkopf, Florian Seufert, Jens Schmitz, Laura E. Marshall, Andrew E. Scott, Isobel H. Norville, Peter J. Myler, Ulrike Holzgrabe, Nicholas J. Harmer, Mitali Sarkar-Tyson
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:1625-1634
Background The macrophage infectivity potentiator (Mip) protein, which belongs to the immunophilin superfamily, is a peptidyl-prolyl cis/trans isomerase (PPIase) enzyme. Mip has been shown to be important for virulence in a wide range of pathogenic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ca13736e17f6f376896275651f4a70
https://doi.org/10.1093/jac/dkac065
https://doi.org/10.1093/jac/dkac065
Autor:
Dimitri Wilms, Tilo Pompe, J. Döring, Kai Ostermann, Florian Seufert, David Rettke, Stephan Schmidt
Publikováno v:
Biosensorsbioelectronics. 192
An increasing number of reports substantiate the link between emerging estrogenic pollutants and a variety of adverse effects including developmental disorders, infertility, cancer and neurological disorders, threatening public health as well as envi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ed9d1baf9597fb3a0f087380b2b99d
https://pubmed.ncbi.nlm.nih.gov/34325320
https://pubmed.ncbi.nlm.nih.gov/34325320
Autor:
Charlene M. Kahler, Jutta Ebert, Vera Kozjak-Pavlovic, Anastasija Reimer, Mitali Sarkar-Tyson, Nicole M. Bzdyl, Ulrike Holzgrabe, Matthias Weiwad, Florian Seufert, Thomas Rudel
Publikováno v:
International Journal of Antimicrobial Agents. 48:401-408
The pathogenic bacteria Chlamydia trachomatis, Neisseria gonorrhoeae and Neisseria meningitidis express the surface-exposed macrophage infectivity potentiator (MIP)-like protein, which plays a role in their pathogenicity. MIP exhibits a peptidyl-prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b276189041ba9798c6a96e4d0276e5c5
https://doi.org/10.1016/j.ijantimicag.2016.06.020
https://doi.org/10.1016/j.ijantimicag.2016.06.020
Publikováno v:
Nachrichten aus der Chemie. 64:605-609
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c35ffd44ad87e5bbb1482cd4f1914fd
https://doi.org/10.1002/nadc.20164046023
https://doi.org/10.1002/nadc.20164046023