Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Florian Schmieder"'
Autor:
Claudia Dittfeld, Florian Schmieder, Stephan Behrens, Anett Jannasch, Klaus Matschke, Frank Sonntag, Sems-Malte Tugtekin
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-14 (2024)
Abstract Introduction Microphysiological systems (MPS) offer simulation of (patho)physiological parameters. Investigation includes items which lead to fibrosis and calcification in development and progress of calcific aortic valve disease, based e.g.
Externí odkaz:
https://doaj.org/article/802dbf0b3cca4177bdb170241ad7ef5f
Autor:
Claudia Dittfeld, Maximilian Winkelkotte, Anna Scheer, Emmely Voigt, Florian Schmieder, Stephan Behrens, Anett Jannasch, Klaus Matschke, Frank Sonntag, Sems-Malte Tugtekin
Publikováno v:
Journal of Biological Engineering, Vol 17, Iss 1, Pp 1-19 (2023)
Abstract Background Calcific aortic valve disease (CAVD) causes an increasing health burden in the 21st century due to aging population. The complex pathophysiology remains to be understood to develop novel prevention and treatment strategies. Microp
Externí odkaz:
https://doaj.org/article/d2191eea763c4b93a1315f43e65709fc
Autor:
Ina Prade, Michaela Schröpfer, Caroline Seidel, Claudia Krumbiegel, Tina Hille, Frank Sonntag, Stephen Behrens, Florian Schmieder, Birgit Voigt, Michael Meyer
Publikováno v:
Biomaterials and Biosystems, Vol 8, Iss , Pp 100067- (2022)
Fiber-shaped materials have great potential for tissue engineering applications as they provide structural support and spatial patterns within a three-dimensional construct. Here we demonstrate the fabrication of mechanically stable, meter-long colla
Externí odkaz:
https://doaj.org/article/94b6fef38fb84fabb41437878ad71f48
Autor:
Negin Namazian Jam, Felix Gottlöber, Melanie Hempel, Yuliya Dzekhtsiarova, Stephan Behrens, Frank Sonntag, Jan Sradnick, Christian Hugo, Florian Schmieder
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 2045 (2023)
Despite disadvantages, such as high cost and their poor predictive value, animal experiments are still the state of the art for pharmaceutical substance testing. One reason for this problem is the inability of standard cell culture methods to emulate
Externí odkaz:
https://doaj.org/article/e33315a6a2b049b29e042def37535939
Autor:
Wiebke Sihver, Anne-Kathrin Nitt-Weber, Stephan Behrens, Martin Ullrich, Hans-Jürgen Pietzsch, Negin Namazian Jam, Florian Schmieder, Frank Sonntag
Publikováno v:
Current Directions in Biomedical Engineering. 8:532-535
Radiopharmaceuticals can be used for targetspecific functional diagnostics, such as PET or SPECT imaging, or radionuclide therapy of diseased tissue, depending on the incorporated radionuclide. Following initial in vitro testing, radiopharmaceutical
Autor:
Daniel Schneider, Stephan Behrens, Jürgen Philipp, Jiri Eitler, Julian Stumpf, Torsten Tonn, Frank Sonntag, Christian Hugo, Florian Schmieder
Publikováno v:
Current Directions in Biomedical Engineering. 8:501-504
Antibody-mediated rejection after kidney transplantation is a major limitation for long-term survival of donated kidneys within the recipient allograft. With the existing HLA cross-matching test only complement activating donor specific antibodies ar
Autor:
Stephan Behrens, Florian Schmieder, Klaus Matschke, Anett Jannasch, Claudia Dittfeld, Sems-Malte Tugtekin, Frank Sonntag, M Winkelkotte
Publikováno v:
Clinical Hemorheology and Microcirculation. 79:167-178
BACKGROUND/AIM: Tissue pathogenesis of aortic valve (AV) stenosis is research focus in cardiac surgery. Model limitations of conventional 2D culture of human or porcine valvular interstitial/endothelial cells (VIC/VECs) isolated from aortic valve tis
Autor:
Sebastian Böhlen, Sebastian Konzok, Jennifer Labisch, Susann Dehmel, Dirk Schaudien, Stephan Behrens, Florian Schmieder, Armin Braun, Frank Sonntag, Katherina Sewald
Publikováno v:
Current Directions in Biomedical Engineering, Vol 7, Iss 2, Pp 207-210 (2021)
Current in vitro and in vivo disease models have been reported to lack sufficient translation to human. Precision-Cut Lung Slices (PCLS) are viable sections of lung tissue and have been described to be a translational model for the ex vivo assessment
Autor:
Juliane Valtin, Stephan Behrens, Manfred F. Maitz, Florian Schmieder, Frank Sonntag, Carsten Werner
Publikováno v:
Current Directions in Biomedical Engineering, Vol 7, Iss 2, Pp 171-174 (2021)
Newly developed materials for blood-contacting devices need to undergo hemocompatibility testing to prove compliance with clinical requirements. However, many current in vitro models disregard the influence of flow conditions and blood exchange as it
Publikováno v:
Current Directions in Biomedical Engineering, Vol 6, Iss 3, Pp 135-138 (2020)
Within the human blood immune cells assume specific functions to modulate and control the human immune response. Consequently, they are used for the diagnosis and treatment of autoimmune and hematologic diseases. Traceless Affinity Cell Selection Tec