Zobrazeno 1 - 10
of 335
pro vyhledávání: '"Florian Schmidt, A."'
Autor:
Mohammad Amin Honardoost, Andreas Adinatha, Florian Schmidt, Bobby Ranjan, Maryam Ghaeidamini, Nirmala Arul Rayan, Michelle Gek Liang Lim, Ignasius Joanito, Quy Xiao Xuan Lin, Deepa Rajagopalan, Shi Qi Mok, You Yi Hwang, Anis Larbi, Chiea Chuen Khor, Roger Foo, Bernhard Otto Boehm, Shyam Prabhakar
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-24 (2024)
Abstract Background Type 1 diabetes mellitus (T1DM) is a prototypic endocrine autoimmune disease resulting from an immune-mediated destruction of pancreatic insulin-secreting $$\beta$$ β cells. A comprehensive immune cell phenotype evaluation in T1D
Externí odkaz:
https://doaj.org/article/c994264bbf6c46a98457293f3fbf1308
Publikováno v:
Frontiers in Communication, Vol 9 (2024)
In this paper, we consider the issue of how the fine-grained multimodal design of educational explanation videos, such as those widely available on YouTube and other platforms, may be made accessible to empirical studies of reception and effectivenes
Externí odkaz:
https://doaj.org/article/a18010393be2426e8c55a21a7e226d24
Autor:
Piyush Singh, Florian Schmidt, Jochen Wild, Johannes Riemenschneider, Joachim Peinke, Michael Hölling
Publikováno v:
Aerospace, Vol 11, Iss 5, p 353 (2024)
This article presents an experimental investigation of a passive-adaptive slat concept, an aerodynamic control mechanism aimed at avoiding separation in the inwards region of a horizontal axis wind turbine blade. The passive-adaptive slat is designed
Externí odkaz:
https://doaj.org/article/81d342eb05f94e33bd9c71eca82f2842
Autor:
Florian Schmidt, Hannah F. Fields, Yovita Purwanti, Ana Milojkovic, Syazwani Salim, Kan Xing Wu, Yannick Simoni, Antonella Vitiello, Daniel T. MacLeod, Alessandra Nardin, Evan W. Newell, Katja Fink, Andreas Wilm, Michael Fehlings
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113250- (2023)
Summary: Following viral infection, the human immune system generates CD8+ T cell responses to virus antigens that differ in specificity, abundance, and phenotype. A characterization of virus-specific T cell responses allows one to assess infection h
Externí odkaz:
https://doaj.org/article/d6eded1c85f54ddc91bb785b41d88019
Autor:
Alice Rovai, BoMee Chung, Qingluan Hu, Sebastian Hook, Qinggong Yuan, Tibor Kempf, Florian Schmidt, Dirk Grimm, Steven R. Talbot, Lars Steinbrück, Jasper Götting, Jens Bohne, Simon A. Krooss, Michael Ott
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Hemochromatosis is a metabolic disorder caused by mutations in the HFE gene. Here, the authors show that a single administration of AAV8 vectors expressing an Adenine Base Editor facilitates efficient in vivo gene correction in hepatocytes and leads
Externí odkaz:
https://doaj.org/article/41baa3360d14427b871c13b614264a6d
Autor:
Sahin Cangaz, Oliver Lohrberg, Thomas Abendroth, Christian Heubner, Florian Schmidt, Holger Althues, Susanne Dörfler, Alexander Michaelis, Stefan Kaskel
Publikováno v:
Advanced Materials Interfaces, Vol 10, Iss 7, Pp n/a-n/a (2023)
Abstract Columnar silicon (col‐Si) is a great candidate as anode material to achieve volumetric energy density, outperforming state‐of‐the‐art lithium‐ion batteries. The utilization of col‐Si in industrial scale is mainly restricted by po
Externí odkaz:
https://doaj.org/article/9b14e522eaaf4aa385d7b95e9f50d266
Autor:
Alexander Assmann, Andreas Beckmann, Christof Schmid, Karl Werdan, Guido Michels, Oliver Miera, Florian Schmidt, Stefan Klotz, Christoph Starck, Kevin Pilarczyk, Ardawan Rastan, Marion Burckhardt, Monika Nothacker, Ralf Muellenbach, York Zausig, Nils Haake, Heinrich Groesdonk, Markus Ferrari, Michael Buerke, Marcus Hennersdorf, Mark Rosenberg, Thomas Schaible, Harald Köditz, Stefan Kluge, Uwe Janssens, Matthias Lubnow, Andreas Flemmer, Susanne Herber‐Jonat, Lucas Wessel, Dirk Buchwald, Sven Maier, Lars Krüger, Andreas Fründ, Rolf Jaksties, Stefan Fischer, Karsten Wiebe, Christiane S. Hartog, Omer Dzemali, Daniel Zimpfer, Elfriede Ruttmann‐Ulmer, Christian Schlensak, Malte Kelm, Stephan Ensminger, Udo Boeken
Publikováno v:
ESC Heart Failure, Vol 9, Iss 1, Pp 506-518 (2022)
Abstract Aims Worldwide applications of extracorporeal circulation for mechanical support in cardiac and circulatory failure, which are referred to as extracorporeal life support (ECLS) or veno‐arterial extracorporeal membrane oxygenation (va‐ECM
Externí odkaz:
https://doaj.org/article/3cc42e08b8b74e6c906acd34a5786ace
Publikováno v:
Frontiers in Education, Vol 8 (2023)
Psychological factors play an important role in higher education. With respect to students' understanding of scientific research methods, research self-efficacy (RSE) has been studied as a core construct. However, findings on antecedents and outcomes
Externí odkaz:
https://doaj.org/article/5613d115d1474284b0b77416302755b0
Autor:
Chady H. Hakim, Sandeep R. P. Kumar, Dennis O. Pérez-López, Nalinda B. Wasala, Dong Zhang, Yongping Yue, James Teixeira, Xiufang Pan, Keqing Zhang, Emily D. Million, Christopher E. Nelson, Samantha Metzger, Jin Han, Jacqueline A. Louderman, Florian Schmidt, Feng Feng, Dirk Grimm, Bruce F. Smith, Gang Yao, N. Nora Yang, Charles A. Gersbach, Shi-jie Chen, Roland W. Herzog, Dongsheng Duan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The Cas9-specific T cell response has been speculated to impair CRISPR therapy. Here, the authors show that local and systemic AAV CRISPR therapy induces cytotoxic killing and eliminates rescued dystrophin in canine models of Duchenne muscular dystro
Externí odkaz:
https://doaj.org/article/fa789cec57864e868cf64db8cae359c5
Autor:
Bobby Ranjan, Wenjie Sun, Jinyu Park, Kunal Mishra, Florian Schmidt, Ronald Xie, Fatemeh Alipour, Vipul Singhal, Ignasius Joanito, Mohammad Amin Honardoost, Jacy Mei Yun Yong, Ee Tzun Koh, Khai Pang Leong, Nirmala Arul Rayan, Michelle Gek Liang Lim, Shyam Prabhakar
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Cell-type-specific genes are often strongly correlated in expression - an informative yet underexplored property of single-cell data. Here, the authors leverage gene expression correlations to develop DUBStepR, a feature selection method for accurate
Externí odkaz:
https://doaj.org/article/679d215e24a04b659dd516970921da96