Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Florian Sauer"'
Autor:
Isabell Schmidt, Bruno Boemke, Irmela Herzog, Claudia Koppmann, Hannah Witte, Florian Sauer, Erich Claßen, Frank Lehmkuhl
Publikováno v:
Environmental Sciences Europe, Vol 36, Iss 1, Pp 1-18 (2024)
Abstract Background Archaeological sites are increasingly threatened by climate-related hazards. In response, heritage management authorities initiated projects to document damage and plan risk assessment measures. We present a project initiated afte
Externí odkaz:
https://doaj.org/article/2c1251c89f474772a772cd0a389ca4ee
Autor:
Jan Schlötzer, Alexander Schmalix, Sophie Hügelschäffer, Dominic Rieger, Florian Sauer, Mark D Tully, Thomas Rudel, Silke Wiesner, Caroline Kisker
Publikováno v:
PLoS Pathogens, Vol 20, Iss 10, p e1012630 (2024)
The chlamydial deubiquitinase Cdu1 of the obligate intracellular human pathogenic bacterium Chlamydia trachomatis plays important roles in the maintenance of chlamydial infection. Despite the structural similarities shared with its homologue Cdu2, bo
Externí odkaz:
https://doaj.org/article/c94475afcd1844e7a7f706d26e27b07e
Autor:
Stefan Peissert, Florian Sauer, Daniel B. Grabarczyk, Cathy Braun, Gudrun Sander, Arnaud Poterszman, Jean-Marc Egly, Jochen Kuper, Caroline Kisker
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
XPD is part of the TFIIH complex which plays major roles in transcription initiation and nucleotide excision repair (NER). Here the authors present a high-resolution crystal structure of the XPD-MAT1 interface and dissect the role of this interface i
Externí odkaz:
https://doaj.org/article/52a2dac0f1f34c4a966c28ea3af6e495
Autor:
Emily C. Beckwitt, Sunbok Jang, Isadora Carnaval Detweiler, Jochen Kuper, Florian Sauer, Nina Simon, Johanna Bretzler, Simon C. Watkins, Thomas Carell, Caroline Kisker, Bennett Van Houten
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
It is not fully understood how XPA interacts with a DNA lesion during nucleotide excision repair. Here, the authors use single molecule analysis to study XPA–DNA interactions, including the DNA bend angle, protein stoichiometry, and diffusive prope
Externí odkaz:
https://doaj.org/article/cb2429af2c074e93843b6cd1c155ebba
Autor:
Jürgen Richter, Thomas Litt, Frank Lehmkuhl, Andreas Hense, Thomas C Hauck, Dirk F Leder, Andrea Miebach, Hannah Parow-Souchon, Florian Sauer, Jonathan Schoenenberg, Maysoon Al-Nahar, Shumon T Hussain
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0239968 (2020)
Our field data from the Upper Palaeolithic site of Al-Ansab 1 (Jordan) and from a pollen sequence in the Dead Sea elucidate the role that changing Steppe landscapes played in facilitating anatomically modern human populations to enter a major expansi
Externí odkaz:
https://doaj.org/article/f061dc61078a4bdab1e59f5c210de1c0
Autor:
Thomas Eggers-Kaas, Jesper Borre Pedersen, Christian Steven Hoggard, Florian Sauer, Jan Hilgart, Felix Riede
Publikováno v:
Danish Journal of Archaeology, Vol 8 (2019)
During road construction work, material attributed to the Final Palaeolithic was discovered at Skovmosen I, near Kongens Lyngby on Zealand, eastern Denmark. Although it is regularly mentioned in reviews of the southern Scandinavian Final Palaeolithic
Externí odkaz:
https://doaj.org/article/12661f02831a4520b382bedcff02649f
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
RecQ helicases are important for maintaining genomic integrity. Here, the authors present functional data and the crystal structure of human RecQ4, which exerts a helicase mechanism that may be more closely related to bacterial RecQ helicases than to
Externí odkaz:
https://doaj.org/article/147d31ce692b44a8aba126cc52fb6e05
Autor:
Spyros D Chatziefthimiou, Philipp Hornburg, Florian Sauer, Simone Mueller, Deniz Ugurlar, Emma-Ruoqi Xu, Matthias Wilmanns
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226693 (2019)
In striated muscles, molecular filaments are largely composed of long protein chains with extensive arrays of identically folded domains, referred to as "beads-on-a-string". It remains a largely unresolved question how these domains have developed a
Externí odkaz:
https://doaj.org/article/d0254c6b8eb74b8085f90d3eb325de21
Autor:
Annette Fischer, Kelly S Harrison, Yesid Ramirez, Daniela Auer, Suvagata Roy Chowdhury, Bhupesh K Prusty, Florian Sauer, Zoe Dimond, Caroline Kisker, P Scott Hefty, Thomas Rudel
Publikováno v:
eLife, Vol 6 (2017)
Obligate intracellular Chlamydia trachomatis replicate in a membrane-bound vacuole called inclusion, which serves as a signaling interface with the host cell. Here, we show that the chlamydial deubiquitinating enzyme (Cdu) 1 localizes in the inclusio
Externí odkaz:
https://doaj.org/article/b1e8d22bb1f04a32a1e99d57bb057a2f
Autor:
Jochen Kuper, Cathy Braun, Agnes Elias, Gudrun Michels, Florian Sauer, Dominik R Schmitt, Arnaud Poterszman, Jean-Marc Egly, Caroline Kisker
Publikováno v:
PLoS Biology, Vol 12, Iss 9, p e1001954 (2014)
The eukaryotic XPD helicase is an essential subunit of TFIIH involved in both transcription and nucleotide excision repair (NER). Mutations in human XPD are associated with several inherited diseases such as xeroderma pigmentosum, Cockayne syndrome,
Externí odkaz:
https://doaj.org/article/88cc70ed5c364099a3152604a61d9dd6