Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Florian Rubelt"'
Autor:
Sonwabile Dzanibe, Aaron J. Wilk, Susan Canny, Thanmayi Ranganath, Berenice Alinde, Florian Rubelt, Huang Huang, Mark M. Davis, Susan P. Holmes, Heather B. Jaspan, Catherine A. Blish, Clive M. Gray
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract While preventing vertical HIV transmission has been very successful, HIV-exposed uninfected infants (iHEU) experience an elevated risk to infections compared to HIV-unexposed and uninfected infants (iHUU). Here we present a longitudinal mult
Externí odkaz:
https://doaj.org/article/44079eeedfed4aefb26588fb0716959c
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/f61920ce95d94bb1a5126d2598617833
Autor:
Richard Dannebaum, Phillip Suwalski, Hosseinali Asgharian, Gracie Du Zhipei, Hai Lin, January Weiner, 3rd, Manuel Holtgrewe, Charlotte Thibeault, Melina Müller, Xiaomin Wang, Zehra Karadeniz, Jacopo Saccomanno, Jan-Moritz Doehn, Ralf-Harto Hübner, Bernd Hinzmann, Anja Blüher, Sandra Siemann, Dilduz Telman, Norbert Suttorp, Martin Witzenrath, Stefan Hippenstiel, Carsten Skurk, Wolfgang Poller, Leif E Sander, Dieter Beule, Florian Kurth, Toumy Guettouche, Ulf Landmesser, Jan Berka, Khai Luong, Florian Rubelt, Bettina Heidecker
Publikováno v:
EClinicalMedicine, Vol 48, Iss , Pp 101438- (2022)
Summary: Background: Disease progression of subjects with coronavirus disease 2019 (COVID-19) varies dramatically. Understanding the various types of immune response to SARS-CoV-2 is critical for better clinical management of coronavirus outbreaks an
Externí odkaz:
https://doaj.org/article/ea43228ea981419387b84f56bd729389
Autor:
Ramy A. Arnaout, Eline T. Luning Prak, Nicholas Schwab, Florian Rubelt, the Adaptive Immune Receptor Repertoire Community, Rohit Arora, Rachael Bashford-Rogers, Felix Breden, Syed Ahmad Chan Bukhari, Brian Corrie, Lindsay G. Cowell, Sol Efroni, Christopher Gooley, Victor Greiff, Jason Vander Heiden, Yoshinobu Koguchi, Ton Langerak, Theam Soon Lim, Eline Luning Prak, Encarnita Mariotti-Ferrandiz, Susanna Marquez, Pieter Meysman, Enkelejda Miho, Keshav Motwani, Nima Nouri, Milena Pavlović, Geir Kjetil Sandve, Igor Snapkov, Cinque Soto, Ulrik Stervbo, Johannes Trück, Henk-Jan van den Ham, Corey Watson, Cédric R. Weber
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
It is increasingly clear that an extraordinarily diverse range of clinically important conditions—including infections, vaccinations, autoimmune diseases, transplants, transfusion reactions, aging, and cancers—leave telltale signatures in the mil
Externí odkaz:
https://doaj.org/article/722776cd07cd4898b11d91fbcc3ffabd
Autor:
Scott Christley, Mikhail K. Levin, Inimary T. Toby, John M. Fonner, Nancy L. Monson, William H. Rounds, Florian Rubelt, Walter Scarborough, Richard H. Scheuermann, Lindsay G. Cowell
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-5 (2017)
Abstract Background Pre-processing of high-throughput sequencing data for immune repertoire profiling is essential to insure high quality input for downstream analysis. VDJPipe is a flexible, high-performance tool that can perform multiple pre-proces
Externí odkaz:
https://doaj.org/article/26c993d5cb694e45b75adc076995ae4a
Autor:
Florian Rubelt, Christopher R. Bolen, Helen M. McGuire, Jason A. Vander Heiden, Daniel Gadala-Maria, Mikhail Levin, Ghia M. Euskirchen, Murad R. Mamedov, Gary E. Swan, Cornelia L. Dekker, Lindsay G. Cowell, Steven H. Kleinstein, Mark M. Davis
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The diversity of antigen receptor specificities is largely generated by random recombination of its segments. Here the authors show, by genetic comparison of monozygotic twin lymphocyte subsets, that individual genetic and epigenetic biases also cont
Externí odkaz:
https://doaj.org/article/6853a3a371674e3b9bf79b0d8c6ab451
Autor:
Syed Ahmad Chan Bukhari, Martin J. O’Connor, Marcos Martínez-Romero, Attila L. Egyedi, Debra Willrett, John Graybeal, Mark A. Musen, Florian Rubelt, Kei-Hoi Cheung, Steven H. Kleinstein
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The adaptation of high-throughput sequencing to the B cell receptor and T cell receptor has made it possible to characterize the adaptive immune receptor repertoire (AIRR) at unprecedented depth. These AIRR sequencing (AIRR-seq) studies offer tremend
Externí odkaz:
https://doaj.org/article/e28f95a5137843d3a78e695d29ec81b2
Autor:
Scott Christley, Walter Scarborough, Eddie Salinas, William H. Rounds, Inimary T. Toby, John M. Fonner, Mikhail K. Levin, Min Kim, Stephen A. Mock, Christopher Jordan, Jared Ostmeyer, Adam Buntzman, Florian Rubelt, Marco L. Davila, Nancy L. Monson, Richard H. Scheuermann, Lindsay G. Cowell
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
BackgroundRecent technological advances in immune repertoire sequencing have created tremendous potential for advancing our understanding of adaptive immune response dynamics in various states of health and disease. Immune repertoire sequencing produ
Externí odkaz:
https://doaj.org/article/ccf807b5dbf248eeac1ed7188f9e63bd
Autor:
Felix Breden, Eline T. Luning Prak, Bjoern Peters, Florian Rubelt, Chaim A. Schramm, Christian E. Busse, Jason A. Vander Heiden, Scott Christley, Syed Ahmad Chan Bukhari, Adrian Thorogood, Frederick A. Matsen IV, Yariv Wine, Uri Laserson, David Klatzmann, Daniel C. Douek, Marie-Paule Lefranc, Andrew M. Collins, Tania Bubela, Steven H. Kleinstein, Corey T. Watson, Lindsay G. Cowell, Jamie K. Scott, Thomas B. Kepler
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
High-throughput sequencing (HTS) of immunoglobulin (B-cell receptor, antibody) and T-cell receptor repertoires has increased dramatically since the technique was introduced in 2009 (1–3). This experimental approach explores the maturation of the ad
Externí odkaz:
https://doaj.org/article/baa46033725a4e99b5a18b8f93cfffdc
Autor:
Florian Rubelt, Volker Sievert, Florian Knaust, Christian Diener, Theam Soon Lim, Karl Skriner, Edda Klipp, Richard Reinhardt, Hans Lehrach, Zoltán Konthur
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49774 (2012)
The immune system protects us from foreign substances or pathogens by generating specific antibodies. The variety of immunoglobulin (Ig) paratopes for antigen recognition is a result of the V(D)J rearrangement mechanism, while a fast and efficient im
Externí odkaz:
https://doaj.org/article/9fa5159b836a48eab9ecb7a8f01cde55