Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Florian Rathje"'
Autor:
Tamara Scheidt, Oliver Alka, Humberto Gonczarowska-Jorge, Wolfgang Gruber, Florian Rathje, Margherita Dell’Aica, Marc Rurik, Oliver Kohlbacher, René P. Zahedi, Fritz Aberger, Christian G. Huber
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-18 (2020)
Abstract Background Aberrant hedgehog (HH) signaling is implicated in the development of various cancer entities such as medulloblastoma. Activation of GLI transcription factors was revealed as the driving force upon pathway activation. Increased pho
Externí odkaz:
https://doaj.org/article/274b593e3c1b42f79ca06a9c78081fdb
Publikováno v:
Cancers. 14:5416
Functional studies of primary cancer have been limited to animal models for a long time making it difficult to study aspects specific to human cancer biology. The development of organoid technology enabled us to culture human healthy and tumor cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fb7729f061d387f407f6607011842c
https://doi.org/10.3390/cancers14215416
https://doi.org/10.3390/cancers14215416
Autor:
Mirko Zaja, Filip Vilotic, Gruber Wolfgang, Svetlana Hamm, Elisabeth Peer, Florian Rathje, Sandra Grund-Groeschke, Susanne Michel, Dominik P. Elmer, Sophie Karoline Aichberger, Andrea Ramspacher, Thomas Parigger, Fritz Aberger
(1)BackgroundAberrant activation of the Hedgehog (HH)/GLI pathway in stem-like tumor initiating cells (TIC) is a frequent oncogenic driver signal in various human malignancies. Remarkable efficacy of anti-HH therapeutics led to the approval of HH inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c974e0ac5a8a090f92d797bd468fcc4f
https://doi.org/10.1101/2021.06.17.448773
https://doi.org/10.1101/2021.06.17.448773
Autor:
Cornelia Hauser-Kronberger, Wolfgang Sperl, Johannes A. Mayr, Barbara Kofler, Michael Emberger, Roland Lang, Reinhard Geilberger, René G. Feichtinger, Florian Rathje, Johann W. Bauer
Publikováno v:
Experimental Dermatology. 27:204-207
The Warburg theory of cancer postulates that an important driver of tumorigenesis is insufficient respiration due to mitochondrial defects, and concomitant enhancement of lactate production due to increased aerobic glycolysis. We analysed 48 melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3054cf0633b14ef8ec831a4bbfce11
https://doi.org/10.1111/exd.13465
https://doi.org/10.1111/exd.13465