Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Florian Praetorius"'
Autor:
Bastian Bräuning, Eva Bertosin, Florian Praetorius, Christian Ihling, Alexandra Schatt, Agnes Adler, Klaus Richter, Andrea Sinz, Hendrik Dietz, Michael Groll
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The Yersinia YaxAB system is a pore-forming toxin of so far unknown structure. Here authors present X-ray and cryo-EM to structures of individual subunits and of the YaxAB pore complex, and find that YaxA binds to membranes first and recruits YaxB fo
Externí odkaz:
https://doaj.org/article/b58d61f8141a4986b198653b2a2a0a9c
Autor:
Natasha I Edman, Rachel L Redler, Ashish Phal, Thomas Schlichthaerle, Sanjay R Srivatsan, Ali Etemadi, Seong An, Andrew Favor, Devon Ehnes, Zhe Li, Florian Praetorius, Max Gordon, Wei Yang, Brian Coventry, Derrick R Hicks, Longxing Cao, Neville Bethel, Piper Heine, Analisa N Murray, Stacey Gerben, Lauren Carter, Marcos Miranda, Babak Negahdari, Sangwon Lee, Cole Trapnell, Lance Stewart, Damian C Ekiert, Joseph Schlessinger, Jay Shendure, Gira Bhabha, Hannele Ruohola-Baker, David Baker
Publikováno v:
bioRxiv
Growth factors and cytokines signal by binding to the extracellular domains of their receptors and drive association and transphosphorylation of the receptor intracellular tyrosine kinase domains, initiating downstream signaling cascades. To enable s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cabf19b52c9e40ae334b69d4789b7567
https://europepmc.org/articles/PMC10055045/
https://europepmc.org/articles/PMC10055045/
Autor:
Florian Praetorius, Philip J. Y. Leung, Maxx H. Tessmer, Adam Broerman, Cullen Demakis, Acacia F. Dishman, Arvind Pillai, Abbas Idris, David Juergens, Justas Dauparas, Xinting Li, Paul M. Levine, Mila Lamb, Ryanne K. Ballard, Stacey R. Gerben, Hannah Nguyen, Alex Kang, Banumathi Sankaran, Asim K. Bera, Brian F. Volkman, Jeff Nivala, Stefan Stoll, David Baker
Proteins that switch between two structural states as a function of environmental stimuli are widespread in nature. These proteins structurally transduce biochemical information in a manner analogous to how transistors control information flow in com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ffd869139e74a9969afeb1fde7c1d01
https://doi.org/10.1101/2023.01.27.525968
https://doi.org/10.1101/2023.01.27.525968
Autor:
Danny D. Sahtoe, Florian Praetorius, Alexis Courbet, Yang Hsia, Basile I. M. Wicky, Natasha I. Edman, Lauren M. Miller, Bart J. R. Timmermans, Justin Decarreau, Hana M. Morris, Alex Kang, Asim K. Bera, David Baker
Publikováno v:
Science. 375
Asymmetric multiprotein complexes that undergo subunit exchange play central roles in biology but present a challenge for design because the components must not only contain interfaces that enable reversible association but also be stable and well be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7906ff67d195ff1a34a05f7b985ecd2f
https://doi.org/10.1126/science.abj7662
https://doi.org/10.1126/science.abj7662
Autor:
Lauren Miller, David Baker, Natasha I. Edman, Bart J. R. Timmermans, Basile I. M. Wicky, Asim K. Bera, Danny D. Sahtoe, Hana M. Morris, Florian Praetorius, Alexis Courbet, Yang Hsia, Alex Kang
Asymmetric multi-protein complexes that undergo subunit exchange play central roles in biology, but present a challenge for protein design. The individual components must contain interfaces enabling reversible addition to and dissociation from the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45fc92d25d4e26880d05c7f103e50a0c
https://doi.org/10.1101/2021.08.15.456388
https://doi.org/10.1101/2021.08.15.456388
Autor:
Florian Praetorius, Dirk Weuster-Botz, Benjamin Kick, Karl L. Behler, Hendrik Dietz, Maximilian N. Honemann
Publikováno v:
Nature. 552:84-87
DNA nanotechnology, in particular DNA origami, enables the bottom-up self-assembly of micrometre-scale, three-dimensional structures with nanometre-precise features. These structures are customizable in that they can be site-specifically functionaliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed608d06e695775c2464dfbc04722af5
https://doi.org/10.1038/nature24650
https://doi.org/10.1038/nature24650
Publikováno v:
Biotechnology and Bioengineering. 114:777-784
The bacteriophage M13 has found frequent applications in nanobiotechnology due to its chemically and genetically tunable protein surface and its ability to self-assemble into colloidal membranes. Additionally, its single-stranded (ss) genome is commo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5239620fed4f97af0aa7736369c9df02
https://doi.org/10.1002/bit.26200
https://doi.org/10.1002/bit.26200
Publikováno v:
ACS Nano. 10:9156-9164
One key goal of DNA nanotechnology is the bottom-up construction of macroscopic crystalline materials. Beyond applications in fields such as photonics or plasmonics, DNA-based crystal matrices could possibly facilitate the diffraction-based structura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a5c69d674816b1b423dae90fcd14f2
https://doi.org/10.1021/acsnano.6b04787
https://doi.org/10.1021/acsnano.6b04787
Publikováno v:
Nano Letters
Scaffolded DNA origami enables the fabrication of a variety of complex nanostructures that promise utility in diverse fields of application, ranging from biosensing over advanced therapeutics to metamaterials. The broad applicability of DNA origami a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c3432175c3782072ec26e827d6e8f5
https://doi.org/10.1021/acs.nanolett.5b01461
https://doi.org/10.1021/acs.nanolett.5b01461
Autor:
Florian Praetorius, Hendrik Dietz, Alexandra Schatt, Michael Groll, Christian Ihling, Andrea Sinz, Bastian Bräuning, Klaus Richter, Eva Bertosin, Agnes Adler
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Pore-forming toxins (PFT) are virulence factors that transform from soluble to membrane-bound states. The Yersinia YaxAB system represents a family of binary α-PFTs with orthologues in human, insect, and plant pathogens, with unknown structures. Yax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d7b2ef1cd4d355b3f30e1af4e2d29c
https://pubmed.ncbi.nlm.nih.gov/29728606
https://pubmed.ncbi.nlm.nih.gov/29728606