Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Florian PE"'
Autor:
Florian Perrin, Lauren C. Anderson, Shane P. C. Mitchell, Priyanka Sinha, Yuliia Turchyna, Masato Maesako, Mei C. Q. Houser, Can Zhang, Steven L. Wagner, Rudolph E. Tanzi, Oksana Berezovska
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-17 (2024)
Abstract The recently discovered interaction between presenilin 1 (PS1), a subunit of γ-secretase involved in amyloid-β (Aβ) peptide production, and GLT-1, the major brain glutamate transporter (EAAT2 in the human), may link two pathological aspec
Externí odkaz:
https://doaj.org/article/ca2040f77bea44028933d446ce3fab62
Autor:
Florian Peters, Stefan Raith, Anna Bock, Kristian Kniha, Mark Ooms, Stephan Christian Möhlhenrich, Frank Hölzle, Ali Modabber
Publikováno v:
Head & Face Medicine, Vol 20, Iss 1, Pp 1-7 (2024)
Abstract Background Tumorous diseases of the jaw demand effective treatments, often involving continuity resection of the jaw. Reconstruction via microvascular bone flaps, like deep circumflex iliac artery flaps (DCIA), is standard. Computer aided pl
Externí odkaz:
https://doaj.org/article/3341721076e249e3af7178da010dbdb6
Autor:
Florian Peterssen, Marlon Schlemminger, Clemens Lohr, Raphael Niepelt, Richard Hanke-Rauschenbach, Rolf Brendel
Publikováno v:
Advances in Applied Energy, Vol 15, Iss , Pp 100181- (2024)
Linear programs are frequently employed to optimize national energy system models, which are used to find a minimum-cost energy system. For the operation, they assume perfect forecasting of the weather and demands over the whole optimization horizon
Externí odkaz:
https://doaj.org/article/309497b6afff4652902a6f39ea6fd344
Autor:
Marlon Schlemminger, Clemens Lohr, Florian Peterssen, Dennis Bredemeier, Raphael Niepelt, Astrid Bensmann, Richard Hanke-Rauschenbach, Michael H. Breitner, Rolf Brendel
Publikováno v:
Energy Strategy Reviews, Vol 55, Iss , Pp 101502- (2024)
In densely populated countries, land competition is a key challenge in light of a growing population and the land-intensive decarbonization of energy supply. We apply an energy system model using linear optimization to Germany as an example for a den
Externí odkaz:
https://doaj.org/article/ea67b968c7c74db7984ef4ee70cd21d6
Autor:
Florian Pernin, Qiao-Ling Cui, Abdulshakour Mohammadnia, Milton G. F. Fernandes, Jeffery A. Hall, Myriam Srour, Roy W. R. Dudley, Stephanie E. J. Zandee, Wendy Klement, Alexandre Prat, Hannah E. Salapa, Michael C. Levin, G. R. Wayne Moore, Timothy E. Kennedy, Christine Vande Velde, Jack P. Antel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Oligodendrocyte (OL) injury and subsequent loss is a pathologic hallmark of multiple sclerosis (MS). Stress granules (SGs) are membrane-less organelles containing mRNAs stalled in translation and considered as participants of the cellular re
Externí odkaz:
https://doaj.org/article/7ecd4f332096485d86164c4aeb9e24fc
Autor:
Janis Gerhardt-Mörsdorf, Florian Peterssen, Paula Burfeind, Mareike Benecke, Boris Bensmann, Richard Hanke-Rauschenbach, Christine Minke
Publikováno v:
Advanced Energy & Sustainability Research, Vol 5, Iss 4, Pp n/a-n/a (2024)
This study performs a cradle‐to‐grave life cycle assessment of a 5 MW proton exchange membrane water electrolysis plant. The analysis follows a thorough engineering‐based bottom‐up design based on the electrochemical model of the system. Thre
Externí odkaz:
https://doaj.org/article/2d05b82df8454789a66256a90e34d191
Autor:
Nuria Tubío-Santamaría, Ashok Kumar Jayavelu, Tina M. Schnoeder, Theresa Eifert, Chen-Jen Hsu, Florian Perner, Qirui Zhang, Daniela V. Wenge, Fynn M. Hansen, Joanna M. Kirkpatrick, Nidhi Jyotsana, Steven W. Lane, Björn von Eyss, Aniruddha J. Deshpande, Michael W. M. Kühn, Juerg Schwaller, Clemens Cammann, Ulrike Seifert, Frédéric Ebstein, Elke Krüger, Andreas Hochhaus, Michael Heuser, Alessandro Ori, Matthias Mann, Scott A. Armstrong, Florian H. Heidel
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-21 (2023)
Abstract Pharmacologic targeting of chromatin-associated protein complexes has shown significant responses in KMT2A-rearranged (KMT2A-r) acute myeloid leukemia (AML) but resistance frequently develops to single agents. This points to a need for thera
Externí odkaz:
https://doaj.org/article/32a44bd3490c43d78d23fc64b13aaac5
Autor:
Priyanka Sinha, Yuliia Turchyna, Shane Patrick Clancy Mitchell, Michael Sadek, Gokce Armagan, Florian Perrin, Masato Maesako, Oksana Berezovska
Publikováno v:
Cells, Vol 13, Iss 19, p 1600 (2024)
Glutamate transporter-1 (GLT-1) dynamics are implicated in excitotoxicity and Alzheimer’s disease (AD) progression. Early stages of AD are often marked by hyperactivity and increased epileptiform activity preceding cognitive decline. Previously, we
Externí odkaz:
https://doaj.org/article/3969f56997554ee5b81d014eef26075a
Autor:
Jan Thorbow, Andrea Strauch, Viktoria Pfening, Jan-Philip Klee, Patricia Brücher, Björn Boshof, Florian Petry, Peter Czermak, Maria Beatriz Herrera Sanchez, Denise Salzig
Publikováno v:
Bioengineering, Vol 11, Iss 7, p 692 (2024)
The assessment of human liver stem cells (HLSCs) as cell therapeutics requires scalable, controlled expansion processes. We first focused on defining appropriate process parameters for HLSC expansion such as seeding density, use of antibiotics, optim
Externí odkaz:
https://doaj.org/article/e4203bea3ee140928a721baaf9c45d10
Autor:
Mark Ooms, Lisa Ponke, Philipp Winnand, Marius Heitzer, Florian Peters, Tim Steiner, Frank Hölzle, Ali Modabber
Publikováno v:
World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-9 (2023)
Abstract Background Intraoperative additional resection (IAR) of initially microscopically involved soft tissue resection margins negatively impacts tumor recurrence in oral squamous cell carcinoma (OSCC). Increasing the selected initial macroscopic
Externí odkaz:
https://doaj.org/article/469a82cbf30f41ab9aaa226b3e5a9dc4