Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Florian Noack"'
Autor:
Florian Noack, Federico Calegari
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Epigenetic modifications of DNA and chromatin are long known to control stem cell differentiation and organ function but the role of similar modifications at the level or regulatory RNAs is just beginning to emerge. Over 160 RNA modifications have be
Externí odkaz:
https://doaj.org/article/70b910af903c47ad907232deb4fc5cde
Autor:
Aditi Singh, Arun Mahesh, Florian Noack, Beatriz Cardoso de Toledo, Federico Calegari, Vijay K. Tiwari
Publikováno v:
Singh, A, Mahesh, A, Noack, F, Cardoso de Toledo, B, Calegari, F & Tiwari, V K 2022, ' Tcf12 and NeuroD1 cooperatively drive neuronal migration during cortical development. ', Development (Cambridge, England), vol. 149, no. 3 . https://doi.org/10.1242/dev.200250
Corticogenesis consists of a series of synchronised events, including fate transition of cortical progenitors, neuronal migration, specification and connectivity. NeuroD1, a basic helix-loop-helix (bHLH) transcription factor (TF), contributes to all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af3faabc51e726743482afcc731a253
https://pure.qub.ac.uk/en/publications/fd8bcbf3-8176-474b-ac17-5b502fca0136
https://pure.qub.ac.uk/en/publications/fd8bcbf3-8176-474b-ac17-5b502fca0136
Autor:
Florian Noack, Silvia Vangelisti, Gerald Raffl, Madalena Carido, Jeisimhan Diwakar, Faye Chong, Boyan Bonev
Publikováno v:
Nat. Neurosci. 25, 154-167 (2022)
How multiple epigenetic layers and transcription factors (TFs) interact to facilitate brain development is largely unknown. Here, to systematically map the regulatory landscape of neural differentiation in the mouse neocortex, we profiled gene expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5be1a1a30377fe23e535e2dbe6d2a0
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64241
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64241
Publikováno v:
Synthesis. 51:2039-2057
Steroids have long been sought after as synthetic targets. Their rearranged counterparts, though, have only recently received more attention, when isolation and biological testing programs revealed several molecular entities that were both structural
Despite huge advances in stem-cell, single-cell and epigenetic technologies, the precise molecular mechanisms that determine lineage specification remain largely unknown. Applying an integrative multiomics approach, e.g. combining single-cell RNA-seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1172909047400e7df35727906aeb0707
https://doi.org/10.1101/2020.08.07.241828
https://doi.org/10.1101/2020.08.07.241828
Publikováno v:
Synthesis. 50:809-820
Benzilic acid rearrangement of i-steroid ketones and their subsequent opening gives access to 5(6→7)abeo-steroids. The functional group tolerance is demonstrated by several examples, including substrates with additional olefinic groups. The method
Autor:
Frank Buchholz, Vijay K. Tiwari, Federico Calegari, Florian Noack, Martin W. Schneider, Abhijeet Pataskar
Publikováno v:
Noack, F, Pataskar, A, Schneider, M, Buchholz, F, Tiwari, V K & Calegari, F 2019, ' Assessment and site-specific manipulation of DNA (hydroxy-)methylation during mouse corticogenesis ', Life science alliance, vol. 2, no. 2, e201900331 . https://doi.org/10.26508/lsa.201900331
Life Science Alliance
Life Science Alliance
This work describes the dynamics of DNA modifications in specific cell types of the developing mammalian cortex. By providing a new method to manipulate this process in vivo, it is shown how this process can influence brain formation.
Dynamic ch
Dynamic ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9faec954dbb9aba69ac8fee5c7ecd5bf
https://pure.qub.ac.uk/en/publications/assessment-and-sitespecific-manipulation-of-dna-hydroxymethylation-during-mouse-corticogenesis(5045d2fd-029e-4392-9b8d-b8e09c092166).html
https://pure.qub.ac.uk/en/publications/assessment-and-sitespecific-manipulation-of-dna-hydroxymethylation-during-mouse-corticogenesis(5045d2fd-029e-4392-9b8d-b8e09c092166).html
Autor:
Sabine Rörig, Florian Noack
Publikováno v:
Sportunterricht in der Berufsbildung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bfec292351918f817765203fff44cf9
https://doi.org/10.5771/9783840313035-301
https://doi.org/10.5771/9783840313035-301
Publikováno v:
Journal of the American Chemical Society. 138:12364-12367
Total syntheses of oridamycin A, triptoquinones B and C, and isoiresin are accomplished from a common intermediate prepared via iridium-catalyzed alcohol C-H tert-(hydroxy)prenylation - a byproduct-free process that forms an all-carbon quaternary ste
Autor:
Vijay K. Tiwari, Tobias Straub, Pawel Smialowski, Johannes Jung, Federico Calegari, Florian Noack, Abhijeet Pataskar
Publikováno v:
The EMBO journal. 35(1)
Cell fate specification relies on the action of critical transcription factors that become available at distinct stages of embryonic development. One such factor is NeuroD1, which is essential for eliciting the neuronal development program and posses