Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Florian M. Pauler"'
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103168- (2024)
Summary: The lineage relationship of clonally-related cells offers important insights into the ontogeny and cytoarchitecture of the brain in health and disease. Here, we provide a protocol to concurrently assess cell lineage relationship and cell-typ
Externí odkaz:
https://doaj.org/article/950d6cbdad744fb5acdcfe5c67577cc8
Autor:
Susanne Laukoter, Robert Beattie, Florian M. Pauler, Nicole Amberg, Keiichi I. Nakayama, Simon Hippenmeyer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
How the imprinted Cdkn1c locus regulates corticogenesis is unclear. Here, the authors dissect the level of cell-autonomy of imprinted Cdkn1c gene function in mouse corticogenesis and identify this as regulating radial glial progenitor cell and projec
Externí odkaz:
https://doaj.org/article/30a406ce09274ca2817830f81bfa62fe
Autor:
Tamara Casteels, Yufeng Zhang, Thomas Frogne, Caterina Sturtzel, Charles-Hugues Lardeau, Ilke Sen, Xiaocheng Liu, Shangyu Hong, Florian M. Pauler, Thomas Penz, Marlene Brandstetter, Charlotte Barbieux, Ekaterine Berishvili, Thomas Heuser, Christoph Bock, Christian G. Riedel, Dirk Meyer, Martin Distel, Jacob Hecksher-Sørensen, Jin Li, Stefan Kubicek
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101329- (2021)
Objective: The loss of forkhead box protein O1 (FoxO1) signaling in response to metabolic stress contributes to the etiology of type II diabetes, causing the dedifferentiation of pancreatic beta cells to a cell type reminiscent of endocrine progenito
Externí odkaz:
https://doaj.org/article/a0e438a3cef045b6a78157d78619e54d
Autor:
Juan Carlos Higareda-Almaraz, Michael Karbiener, Maude Giroud, Florian M. Pauler, Teresa Gerhalter, Stephan Herzig, Marcel Scheideler
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Background Norepinephrine (NE) signaling has a key role in white adipose tissue (WAT) functions, including lipolysis, free fatty acid liberation and, under certain conditions, conversion of white into brite (brown-in-white) adipocytes. Howev
Externí odkaz:
https://doaj.org/article/81c9fe23af9c4541ab276bc24ba9fb5e
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100215- (2020)
Summary: Mosaic analysis with double markers (MADM) technology enables concomitant fluorescent cell labeling and induction of uniparental chromosome disomy (UPD) with single-cell resolution. In UPD, imprinted genes are either overexpressed 2-fold or
Externí odkaz:
https://doaj.org/article/936b6a58a3ed4addb9d2dfdc67b27893
Publikováno v:
Frontiers in Education, Vol 5 (2020)
Scientific research is to date largely restricted to wealthy laboratories in developed nations due to the necessity of complex and expensive equipment. This inequality limits the capacity of science to be used as a diplomatic channel. Maker movements
Externí odkaz:
https://doaj.org/article/5b343a247fe748958a56606c7723f35e
Autor:
Iveta Yotova, Quanah J. Hudson, Florian M. Pauler, Katharina Proestling, Isabella Haslinger, Lorenz Kuessel, Alexandra Perricos, Heinrich Husslein, René Wenzl
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8385 (2021)
Endometriosis is a common gynecological disorder characterized by ectopic growth of endometrium outside the uterus and is associated with chronic pain and infertility. We investigated the role of the long intergenic noncoding RNA 01133 (LINC01133) in
Externí odkaz:
https://doaj.org/article/97fde8b6ed9e4a82846623e8b7cf4c77
Autor:
Giselle Cheung, Florian M. Pauler, Peter Koppensteiner, Thomas Krausgruber, Carmen Streicher, Martin Schrammel, Natalie Gutmann-Özgen, Alexis E. Ivec, Christoph Bock, Ryuichi Shigemoto, Simon Hippenmeyer
SUMMARYThe superior colliculus (SC) in the mammalian midbrain is essential for multisensory integration, attention, and complex behavior (Basso and May, 2017; Cang et al., 2018). The mature SC cytoarchitecture is organized into distinct laminae and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86c055fd1dbc3c9b1cb07d2a7ab54da6
https://doi.org/10.1101/2023.04.16.537059
https://doi.org/10.1101/2023.04.16.537059
Autor:
Daniel Andergassen, Christoph P Dotter, Daniel Wenzel, Verena Sigl, Philipp C Bammer, Markus Muckenhuber, Daniela Mayer, Tomasz M Kulinski, Hans-Christian Theussl, Josef M Penninger, Christoph Bock, Denise P Barlow, Florian M Pauler, Quanah J Hudson
Publikováno v:
eLife, Vol 6 (2017)
To determine the dynamics of allelic-specific expression during mouse development, we analyzed RNA-seq data from 23 F1 tissues from different developmental stages, including 19 female tissues allowing X chromosome inactivation (XCI) escapers to also
Externí odkaz:
https://doaj.org/article/56a76cb9f51a468ea09e84df56a0f1ab
Autor:
Donovan J. Anderson, Florian M. Pauler, Aaron McKenna, Jay Shendure, Simon Hippenmeyer, Marshall S. Horwitz
Publikováno v:
Cell Syst
Mutations are acquired frequently, such that each cell's genome inscribes its history of cell divisions. Common genomic alterations involve loss of heterozygosity (LOH). LOH accumulates throughout the genome, offering large encoding capacity for infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b04274f7e44874b2a335737352dc398
https://europepmc.org/articles/PMC9233029/
https://europepmc.org/articles/PMC9233029/