Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Florian M. Becke"'
Publikováno v:
European Journal of Immunology. 28:257-263
Tumor necrosis factor (TNF) mediates its biological effects by binding to two distinct but homologous receptor molecules. The type 1 receptor (TNF-R1) has been shown to be essential and sufficient for most cellular responses to soluble TNF. In contra
Autor:
Leoni A. Kunz-Schughart, Yaw Chyn Lim, Daniela Drenkard, Herbert Schwarz, Teng Ee Tan, Joachim Langstein, Florian M. Becke, Thilo Spruss
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 21(2)
The cytokine receptor CD137 is a member of the TNF receptor family and a potent T cell costimulatory molecule. Its ligand is expressed on antigen presenting cells as a transmembrane protein and it too can deliver signals into the cells it is expresse
Autor:
Florian M. Becke, Herbert Schwarz, Liane Söllner, Gitte Krause, Marina Kreutz, Reinhard Andreesen, G. Brockhoff, Joachim Langstein
Publikováno v:
Biochemical and biophysical research communications. 273(1)
CD137 (ILA/4-1BB), a member of the TNF receptor family, regulates activation, survival and proliferation of primary human monocytes. Here we compare the activities of lipopolysaccharide (LPS), a classical and potent monocyte activator to that of CD13