Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Florian M, Pauler"'
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103168- (2024)
Summary: The lineage relationship of clonally-related cells offers important insights into the ontogeny and cytoarchitecture of the brain in health and disease. Here, we provide a protocol to concurrently assess cell lineage relationship and cell-typ
Externí odkaz:
https://doaj.org/article/950d6cbdad744fb5acdcfe5c67577cc8
Autor:
Tamara Casteels, Yufeng Zhang, Thomas Frogne, Caterina Sturtzel, Charles-Hugues Lardeau, Ilke Sen, Xiaocheng Liu, Shangyu Hong, Florian M. Pauler, Thomas Penz, Marlene Brandstetter, Charlotte Barbieux, Ekaterine Berishvili, Thomas Heuser, Christoph Bock, Christian G. Riedel, Dirk Meyer, Martin Distel, Jacob Hecksher-Sørensen, Jin Li, Stefan Kubicek
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101329- (2021)
Objective: The loss of forkhead box protein O1 (FoxO1) signaling in response to metabolic stress contributes to the etiology of type II diabetes, causing the dedifferentiation of pancreatic beta cells to a cell type reminiscent of endocrine progenito
Externí odkaz:
https://doaj.org/article/a0e438a3cef045b6a78157d78619e54d
Autor:
Susanne Laukoter, Robert Beattie, Florian M. Pauler, Nicole Amberg, Keiichi I. Nakayama, Simon Hippenmeyer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
How the imprinted Cdkn1c locus regulates corticogenesis is unclear. Here, the authors dissect the level of cell-autonomy of imprinted Cdkn1c gene function in mouse corticogenesis and identify this as regulating radial glial progenitor cell and projec
Externí odkaz:
https://doaj.org/article/30a406ce09274ca2817830f81bfa62fe
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100215- (2020)
Summary: Mosaic analysis with double markers (MADM) technology enables concomitant fluorescent cell labeling and induction of uniparental chromosome disomy (UPD) with single-cell resolution. In UPD, imprinted genes are either overexpressed 2-fold or
Externí odkaz:
https://doaj.org/article/936b6a58a3ed4addb9d2dfdc67b27893
Autor:
Daniel Andergassen, Markus Muckenhuber, Philipp C Bammer, Tomasz M Kulinski, Hans-Christian Theussl, Takahiko Shimizu, Josef M Penninger, Florian M Pauler, Quanah J Hudson
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009151 (2020)
[This corrects the article DOI: 10.1371/journal.pgen.1008268.].
Externí odkaz:
https://doaj.org/article/e3b0679cd3ec4221a2c5e55dd74ef5f1
Publikováno v:
Frontiers in Education, Vol 5 (2020)
Scientific research is to date largely restricted to wealthy laboratories in developed nations due to the necessity of complex and expensive equipment. This inequality limits the capacity of science to be used as a diplomatic channel. Maker movements
Externí odkaz:
https://doaj.org/article/5b343a247fe748958a56606c7723f35e
Autor:
Juan Carlos Higareda-Almaraz, Michael Karbiener, Maude Giroud, Florian M. Pauler, Teresa Gerhalter, Stephan Herzig, Marcel Scheideler
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Background Norepinephrine (NE) signaling has a key role in white adipose tissue (WAT) functions, including lipolysis, free fatty acid liberation and, under certain conditions, conversion of white into brite (brown-in-white) adipocytes. Howev
Externí odkaz:
https://doaj.org/article/81c9fe23af9c4541ab276bc24ba9fb5e
Autor:
Daniel Andergassen, Markus Muckenhuber, Philipp C Bammer, Tomasz M Kulinski, Hans-Christian Theussl, Takahiko Shimizu, Josef M Penninger, Florian M Pauler, Quanah J Hudson
Publikováno v:
PLoS Genetics, Vol 15, Iss 7, p e1008268 (2019)
Long non-coding (lnc) RNAs are numerous and found throughout the mammalian genome, and many are thought to be involved in the regulation of gene expression. However, the majority remain relatively uncharacterised and of uncertain function making the
Externí odkaz:
https://doaj.org/article/7321d8c7237440ca83e2b086f04dd999
Autor:
Giselle Cheung, Florian M. Pauler, Peter Koppensteiner, Thomas Krausgruber, Carmen Streicher, Martin Schrammel, Natalie Gutmann-Özgen, Alexis E. Ivec, Christoph Bock, Ryuichi Shigemoto, Simon Hippenmeyer
SUMMARYThe superior colliculus (SC) in the mammalian midbrain is essential for multisensory integration, attention, and complex behavior (Basso and May, 2017; Cang et al., 2018). The mature SC cytoarchitecture is organized into distinct laminae and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86c055fd1dbc3c9b1cb07d2a7ab54da6
https://doi.org/10.1101/2023.04.16.537059
https://doi.org/10.1101/2023.04.16.537059
Autor:
Daniel Andergassen, Christoph P Dotter, Daniel Wenzel, Verena Sigl, Philipp C Bammer, Markus Muckenhuber, Daniela Mayer, Tomasz M Kulinski, Hans-Christian Theussl, Josef M Penninger, Christoph Bock, Denise P Barlow, Florian M Pauler, Quanah J Hudson
Publikováno v:
eLife, Vol 6 (2017)
To determine the dynamics of allelic-specific expression during mouse development, we analyzed RNA-seq data from 23 F1 tissues from different developmental stages, including 19 female tissues allowing X chromosome inactivation (XCI) escapers to also
Externí odkaz:
https://doaj.org/article/56a76cb9f51a468ea09e84df56a0f1ab