Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Florian Lukas Vetter"'
Publikováno v:
Processes; Volume 11; Issue 4; Pages: 1115
Due to the progressive digitalization of the industry, more and more data is available not only as digitally stored data but also as online data via standardized interfaces. This not only leads to further improvements in process modeling through more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30085b2cc93c14d49029fcfa6e890673
Publikováno v:
Processes
Volume 11
Issue 3
Pages: 745
Volume 11
Issue 3
Pages: 745
The production of messenger ribonucleic acid (mRNA) and other biologics is performed primarily in batch mode. This results in larger equipment, cleaning/sterilization volumes, and dead times compared to any continuous approach. Consequently, producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110a78be97110869c504c7a9bba3e10c
Autor:
Axel Schmidt, Heribert Helgers, Florian Lukas Vetter, Steffen Zobel-Roos, Alina Hengelbrock, Jochen Strube
Publikováno v:
Processes; Volume 10; Issue 9; Pages: 1783
Vaccine supply has a bottleneck in manufacturing capacity due to operation personnel and chemicals needed. Assessment of existing mRNA (messenger ribonucleic acid) vaccine processing show needs for continuous manufacturing processes. This is enabled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42bf428afbf0c6ea3f4e4bf0032da885
Autor:
Heribert Helgers, Alina Hengelbrock, Axel Schmidt, Florian Lukas Vetter, Alex Juckers, Jochen Strube
Publikováno v:
Processes; Volume 10; Issue 5; Pages: 809
Quality-by-Design (QbD) is demanded by regulatory authorities in biopharmaceutical production. Within the QbD frame advanced process control (APC), facilitated through process analytical technology (PAT) and digital twins (DT), plays an increasingly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79cf68c641c6794f8024e887283a57dc
https://dokumente.ub.tu-clausthal.de/servlets/MCRFileNodeServlet/clausthal_derivate_00001881/processes-10-00809.pdf
https://dokumente.ub.tu-clausthal.de/servlets/MCRFileNodeServlet/clausthal_derivate_00001881/processes-10-00809.pdf
Autor:
Florian Lukas Vetter, Jochen Strube
Publikováno v:
Processes; Volume 10; Issue 2; Pages: 373
Crystallization is the main thermal process resulting in the formation of solid products and, therefore, is widely spread in all kinds of industries, from fine chemicals to foods and drugs. For these high-performance products, a quality by design (Qb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c84dff6dbc25ac2042d9fa38e59905f
https://dokumente.ub.tu-clausthal.de/receive/clausthal_mods_00001984
https://dokumente.ub.tu-clausthal.de/receive/clausthal_mods_00001984
Publikováno v:
Processes; Volume 9; Issue 12; Pages: 2121
Preparative and process chromatography is a versatile unit operation for the capture, purification, and polishing of a broad variety of molecules, especially very similar and complex compounds such as sugars, isomers, enantiomers, diastereomers, plan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::f8443ca33d51ca1f710ebe5bfafe20e0
Publikováno v:
Processes, Vol 9, Iss 2121, p 2121 (2021)
Preparative and process chromatography is a versatile unit operation for the capture, purification, and polishing of a broad variety of molecules, especially very similar and complex compounds such as sugars, isomers, enantiomers, diastereomers, plan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3cddb4ab49bcc00cc586d9bdbb450ec2
https://dokumente.ub.tu-clausthal.de/servlets/MCRFileNodeServlet/clausthal_derivate_00001657/processes-09-02121.pdf
https://dokumente.ub.tu-clausthal.de/servlets/MCRFileNodeServlet/clausthal_derivate_00001657/processes-09-02121.pdf
Autor:
Florian Lukas Vetter, Steffen Zobel-Roos, José Paulo Barbosa Mota, Bernt Nilsson, Axel Schmidt, Jochen Strube
Publikováno v:
Processes; Volume 10; Issue 9; Pages: 1868
Funding Information: This research was funded by the Institute for Separation and Process Technology from Clausthal University of Technology and received no external funding. Funding Information: The authors would like to acknowledge their institute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99170d001b3ac6482652b7d6cbf26f8
https://doi.org/10.3390/pr10091868
https://doi.org/10.3390/pr10091868
Autor:
Axel Schmidt, Alex Juckers, Lara Julia Lohmann, Steffen Zobel-Roos, Christoph Jensch, Florian Lukas Vetter, Mourad Mouellef, Jochen Strube, Heribert Helgers
Publikováno v:
Processes, Vol 9, Iss 172, p 172 (2021)
Processes
Volume 9
Issue 1
Processes
Volume 9
Issue 1
Continuous manufacturing opens up new operation windows with improved product quality in contrast to documented lot deviations in batch or fed-batch operations. A more sophisticated process control strategy is needed to adjust operation parameters an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c8076ad5484cd24946f1f6d4c47e44
https://www.mdpi.com/2227-9717/9/1/172
https://www.mdpi.com/2227-9717/9/1/172
Autor:
Alina Hengelbrock, Heribert Helgers, Axel Schmidt, Florian Lukas Vetter, Alex Juckers, Jamila Franca Rosengarten, Jörn Stitz, Jochen Strube
Publikováno v:
Processes; Volume 10; Issue 5; Pages: 866
The development and adoption of digital twins (DT) for Quality-by-Design (QbD)-based processes with flexible operating points within a proven acceptable range (PAR) and automation through Advanced Process Control (APC) with Process Analytical Technol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e687dc5c645564c6e02fc0b6492bc815
https://doi.org/10.3390/pr10050866
https://doi.org/10.3390/pr10050866