Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Florian Le Billan"'
Autor:
Cigdem Sahin, Jenna-Rose Melanson, Florian Le Billan, Lilia Magomedova, Thais A.M. Ferreira, Andressa S. Oliveira, Evan Pollock-Tahari, Michael F. Saikali, Sarah B. Cash, Minna Woo, Luiz A.S. Romeiro, Carolyn L. Cummins
Publikováno v:
Molecular Metabolism, Vol 85, Iss , Pp 101958- (2024)
Objective: The prevalence of metabolic diseases is increasing globally at an alarming rate; thus, it is essential that effective, accessible, low-cost therapeutics are developed. Peroxisome proliferator-activated receptors (PPARs) are transcription f
Externí odkaz:
https://doaj.org/article/cfebdf9a904b44948be866fb0310321e
Autor:
Nathalie Esber, Florian Le Billan, Michèle Resche-Rigon, Hugues Loosfelt, Marc Lombès, Nathalie Chabbert-Buffet
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140795 (2015)
The progesterone receptor (PR) with its isoforms and ligands are involved in breast tumorigenesis and prognosis. We aimed at analyzing the respective contribution of PR isoforms, PRA and PRB, in breast cancer cell proliferation in a new estrogen-inde
Externí odkaz:
https://doaj.org/article/0cb5a5152ee84565b777e549be3e825c
Publikováno v:
Endocrinology.
Steroid hormone signaling pathways are critical for organismal development and act through binding to nuclear receptors driving transcriptional regulation. In this review, we summarize evidence for another – underrated – mechanism of action for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccbf3a9bb7ee4db1db5a41f56a32a494
https://doi.org/10.1210/endocr/bqad081
https://doi.org/10.1210/endocr/bqad081
Autor:
Florian Le Billan, Stephane Angers, Mélanie Robitaille, Henry M. Krause, Quaid Morris, Carolyn L. Cummins, Debashish Ray, Vincent Boivin, Timothy P. Hughes, Benjamin J. Blencowe, Michelle S. Scott, Serge Gueroussov, Rucha Patel, Michael F. Saikali, Lilia Magomedova, Chao Xu, Emma Zilberman, Jens Tiefenbach, Pancharatnam Jeyasuria, Veronique Voisin, Gary D. Bader, Manuel Irimia
Publikováno v:
Nucleic Acids Research
Stress hormones bind and activate the glucocorticoid receptor (GR) in many tissues including the brain. We identified arginine and glutamate rich 1 (ARGLU1) in a screen for new modulators of glucocorticoid signaling in the CNS. Biochemical studies sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6765dcec4b6840322a957c405a3541
http://europepmc.org/articles/PMC6451108
http://europepmc.org/articles/PMC6451108
Autor:
Simon Travers, Julie Perrot, Peter Kolkhof, Marc Lombès, Jérôme Fagart, Elena Carceller, Florian Le Billan, Say Viengchareun
Publikováno v:
FASEB Journal
FASEB Journal, 2021, 35 (2), pp.e21314. ⟨10.1096/fj.202002043RR⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (2), pp.e21314. ⟨10.1096/fj.202002043RR⟩
FASEB Journal, 2021, 35 (2), pp.e21314. ⟨10.1096/fj.202002043RR⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (2), pp.e21314. ⟨10.1096/fj.202002043RR⟩
International audience; Aldosterone, the main mineralocorticoid hormone in humans, plays a pivotal role in the control of water and salt reabsorption via activation of the mineralocorticoid receptor (MR). Alterations in MR signaling pathway lead to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebbb987a5cb8640a838bee0ad99c281
https://doi.org/10.1096/fj.202002043rr
https://doi.org/10.1096/fj.202002043rr
Autor:
Florian Le Billan, Valérie Grange-Messent, Marc Lombès, Sakina Mhaouty-Kodja, Mohsen Ayrout, Stéphanie Chauvin
Publikováno v:
Psychoneuroendocrinology
Psychoneuroendocrinology, Elsevier, 2019, 99, pp.47-56. ⟨10.1016/j.psyneuen.2018.08.034⟩
Psychoneuroendocrinology, Elsevier, 2019, 99, pp.47-56. ⟨10.1016/j.psyneuen.2018.08.034⟩
Stress-induced reproductive dysfunction is frequently associated with increased glucocorticoid (GC) levels responsible for suppressed GnRH/LH secretion and impaired ovulation. Besides the major role of the hypothalamic kisspeptin system, other key re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7740e7b3530a662458f814f0101a1b
https://hal.archives-ouvertes.fr/hal-02400589
https://hal.archives-ouvertes.fr/hal-02400589
Autor:
Larbi Amazit, Anne Guiochon-Mantel, Brigitte Delemer, Florian Le Billan, Jérôme Bouligand, Géraldine Vitellius, Jérôme Fagart, Marc Lombès, Séverine Trabado, Nelly Ramos, Frederic Castinetti
Publikováno v:
Human Mutation. 37:794-803
Generalized glucocorticoid resistance is associated with glucocorticoid receptor (GR; NR3C1) mutations. Three novel heterozygous missense NR3C1 mutations (R477S, Y478C, and L672P) were identified in patients presenting with adrenal incidentalomas, gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3621f0e35c7c40a467a19d1ae6711bff
https://doi.org/10.1002/humu.23008
https://doi.org/10.1002/humu.23008
Autor:
Christophe Lhadj, Qiong-Yao Xue, Peter Kolkhof, Kevin Bleakley, Say Viengchareun, Florian Le Billan, Jérôme Fagart, Eric Pussard, Larbi Amazit, Marc Lombès
Publikováno v:
FASEB Journal
FASEB Journal, 2018, 32 (10), pp.5626-5639. ⟨10.1096/fj.201800391RR⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2018, 32 (10), pp.5626-5639. ⟨10.1096/fj.201800391RR⟩
FASEB Journal, 2018, 32 (10), pp.5626-5639. ⟨10.1096/fj.201800391RR⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2018, 32 (10), pp.5626-5639. ⟨10.1096/fj.201800391RR⟩
Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate major pathophysiologic functions. High homology between these receptors accounts for the crossbinding o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ee4187fa647fc7685416cc6f988fd1
https://pubmed.ncbi.nlm.nih.gov/29733691
https://pubmed.ncbi.nlm.nih.gov/29733691
Autor:
Géraldine, Vitellius, Jérôme, Fagart, Brigitte, Delemer, Larbi, Amazit, Nelly, Ramos, Jérôme, Bouligand, Florian, Le Billan, Frédéric, Castinetti, Anne, Guiochon-Mantel, Séverine, Trabado, Marc, Lombès
Publikováno v:
Human mutation. 37(8)
Generalized glucocorticoid resistance is associated with glucocorticoid receptor (GR; NR3C1) mutations. Three novel heterozygous missense NR3C1 mutations (R477S, Y478C, and L672P) were identified in patients presenting with adrenal incidentalomas, gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8b03cd60305b3158e57ef23f28f2f90f
https://pubmed.ncbi.nlm.nih.gov/27120390
https://pubmed.ncbi.nlm.nih.gov/27120390
Autor:
Say Viengchareun, Jérôme Bouligand, Florian Le Billan, Junaid Ali Khan, Marc Lombès, Jérôme Fagart, Kadhija Lamribet
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2015, in press
FASEB Journal, Federation of American Society of Experimental Biology, 2015, ⟨10.1096/fj.15-274266⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2015, in press
FASEB Journal, Federation of American Society of Experimental Biology, 2015, ⟨10.1096/fj.15-274266⟩
No comment; International audience; © FASEB.Aldosterone exerts its effects mainly by activating the mineralocorticoid receptor (MR), a transcription factor that regulates gene expression through complex and dynamic interactions with coregulators and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e5239c677777e465a02bc04f70f961
https://pubmed.ncbi.nlm.nih.gov/26054365
https://pubmed.ncbi.nlm.nih.gov/26054365