Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Florian Heyl"'
Autor:
Ute A. Hoffmann, Elisabeth Lichtenberg, Said N. Rogh, Raphael Bilger, Viktoria Reimann, Florian Heyl, Rolf Backofen, Claudia Steglich, Wolfgang R. Hess, Annegret Wilde
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 1-18 (2024)
ABSTRACTRNA degradation is critical for synchronising gene expression with changing conditions in prokaryotic and eukaryotic organisms. In bacteria, the preference of the central ribonucleases RNase E, RNase J and RNase Y for 5’-monophosphorylated
Externí odkaz:
https://doaj.org/article/0c276ae73c8d4650852133f254d0e160
Autor:
Saskia Hiltemann, Helena Rasche, Simon Gladman, Hans-Rudolf Hotz, Delphine Larivière, Daniel Blankenberg, Pratik D Jagtap, Thomas Wollmann, Anthony Bretaudeau, Nadia Goué, Timothy J Griffin, Coline Royaux, Yvan Le Bras, Subina Mehta, Anna Syme, Frederik Coppens, Bert Droesbeke, Nicola Soranzo, Wendi Bacon, Fotis Psomopoulos, Cristóbal Gallardo-Alba, John Davis, Melanie Christine Föll, Matthias Fahrner, Maria A Doyle, Beatriz Serrano-Solano, Anne Claire Fouilloux, Peter van Heusden, Wolfgang Maier, Dave Clements, Florian Heyl, Galaxy Training Network, Björn Grüning, Bérénice Batut
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 1, p e1010752 (2023)
There is an ongoing explosion of scientific datasets being generated, brought on by recent technological advances in many areas of the natural sciences. As a result, the life sciences have become increasingly computational in nature, and bioinformati
Externí odkaz:
https://doaj.org/article/418bd96910b049ef9a470281072747d4
Autor:
Ute A. Hoffmann, Elisabeth Lichtenberg, Said N. Rogh, Raphael Bilger, Viktoria Reimann, Florian Heyl, Rolf Backofen, Claudia Steglich, Wolfgang R. Hess, Annegret Wilde
RNA degradation is crucial for many processes in pro- and eukaryotic organisms. In bacteria, the preference of the central ribonucleases RNase E, RNase J and RNase Y towards 5’-monophosphorylated RNAs is considered important for RNA degradation. Fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d7a41e5315b6bb9e3e5d0d17dc31e5d
https://doi.org/10.1101/2023.01.13.523895
https://doi.org/10.1101/2023.01.13.523895
Autor:
Claudia Steglich, Florian Heyl, Said N. Rogh, Thomas Wallner, Wolfgang R. Hess, Ute A. Hoffmann, Rolf Backofen, Annegret Wilde
Ribonucleases are crucial enzymes in RNA metabolism and post-transcriptional regulatory processes in bacteria. Cyanobacteria encode the two essential ribonucleases RNase E and RNase J. Cyanobacterial RNase E is shorter than homologues in other groups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eae900f6952042d25cd60ea4096a1649
https://doi.org/10.1101/2021.07.27.453982
https://doi.org/10.1101/2021.07.27.453982
Autor:
Florian Heyl, Rolf Backofen
Publikováno v:
GigaScience
The prediction of binding sites (peak calling) is a common task in the data analysis of methods such as crosslinking or chromatin immunoprecipitation in combination with high-throughput sequencing (CLIP-Seq, ChIP-Seq). The predicted binding sites are
Publikováno v:
GigaScience
Background Cross-linking and immunoprecipitation followed by next-generation sequencing (CLIP-seq) is the state-of-the-art technique used to experimentally determine transcriptome-wide binding sites of RNA-binding proteins (RBPs). However, it relies
Autor:
Florian Heyl, Bruno Huettel, Wolfgang R. Hess, Anzhela Migur, Janina Fuss, George W. Owttrim, Claudia Steglich, Afshan Srikumar, Rolf Backofen, Jogadhenu S. S. Prakash, Richard Reinhardt
Publikováno v:
Journal of experimental botany.
RNA helicases play crucial functions in RNA biology. In plants, RNA helicases are encoded by large gene families, performing roles in abiotic stress responses, development, the post-transcriptional regulation of gene expression as well as house-keepi
Publikováno v:
GigaScience
Background Post-transcriptional regulation via RNA-binding proteins plays a fundamental role in every organism, but the regulatory mechanisms lack important understanding. Nevertheless, they can be elucidated by cross-linking immunoprecipitation in c
Autor:
Ibrahim Avsar Ilik, Gerd Walz, Barbara Müller, Florian Heyl, Rolf Backofen, Asifa Akhtar, Toma A. Yakulov, Daniel Maticzka, Christina Engel, Luisa Estrada Mallarino, Jörn Dengjel
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Mutations of cilia-associated molecules cause multiple developmental defects that are collectively termed ciliopathies. However, several ciliary proteins, involved in gating access to the cilium, also assume localizations at other cellular sites incl
Autor:
Sarah L. Svensson, Florian Eggenhofer, Florian Heyl, Kathrin Froschauer, Cynthia M. Sharma, Rick Gelhausen, Lydia Hadjeras, Rolf Backofen
Publikováno v:
Bioinformatics
Motivation Ribosome profiling (Ribo-seq) is a powerful approach based on deep sequencing of cDNA libraries generated from ribosome-protected RNA fragments to explore the translatome of a cell, and is especially useful for the detection of small prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76023410438f12af809099ac0a56095
https://doi.org/10.1101/2020.04.27.046219
https://doi.org/10.1101/2020.04.27.046219