Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Florian Heissig"'
Autor:
Christina Gress, Tobias Litzenburger, Ramona Schmid, Ke Xiao, Florian Heissig, Meike Muller, Abhya Gupta, Jens M. Hohlfeld
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Segmental instillation of lipopolysaccharide (LPS) by bronchoscopy safely induces transient airway inflammation in human lungs. This model enables investigation of pulmonary inflammatory mechanisms as well as pharmacodynamic analysis of inve
Externí odkaz:
https://doaj.org/article/561b2cec38ae43e5a0eb80d8141807e5
Autor:
Svante Pääbo, Florian Heissig, Rivka Ravid, Sebastian Zöllner, Gaby G. M. Doxiadis, Wolfgang Enard, Philipp Khaitovich, Patrick Giavalisco, Ajit Varki, Joachim Klose, Ronald E. Bontrop, Kay Nieselt-Struwe, Elaine A. Muchmore
Publikováno v:
Science. 296:340-343
Although humans and their closest evolutionary relatives, the chimpanzees, are 98.7% identical in their genomic DNA sequences, they differ in many morphological, behavioral, and cognitive aspects. The underlying genetic basis of many of these differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8fcc5451f5fc95b158c4716b4147d5
https://doi.org/10.1126/science.1068996
https://doi.org/10.1126/science.1068996
Publikováno v:
Molecular biology and evolution. 24(3)
Mechanisms regulating the cell division cycle are well conserved among all eukaryotes. Consistently many proteins regulating the cell cycle are functionally interchangeable between many organisms. Cell division control is regulated on different level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176431de337afdadc87a4640cdb304ca
https://pubmed.ncbi.nlm.nih.gov/17205977
https://pubmed.ncbi.nlm.nih.gov/17205977
Autor:
Florian, Heissig, Johannes, Krause, Jaroslaw, Bryk, Philipp, Khaitovich, Wolfgang, Enard, Svante, Pääbo
Publikováno v:
Genome Biology
Twelve promoters of genes differentially expressed between humans and chimpanzees were tested for expression activity in culture cells. Seven promoters showed a significant difference in expression level between the human and chimpanzee promoter, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f9a16b2dc2e84b5f13e1c72a55796da9
https://pubmed.ncbi.nlm.nih.gov/15998446
https://pubmed.ncbi.nlm.nih.gov/15998446
Autor:
Gunter Weiss, Xinwei She, Hong Hai Do, Kay Nieselt-Struwe, Ines Hellmann, Florian Heissig, Bjoern Muetzel, Janko Dietzsch, Michael Lachmann, Wolfgang Enard, Stephan Steigele, Svante Pääbo, Philipp Khaitovich, Thomas Arendt, Evan E. Eichler
Publikováno v:
Genome research. 14(8)
We have analyzed gene expression in various brain regions of humans and chimpanzees. Within both human and chimpanzee individuals, the transcriptomes of the cerebral cortex are very similar to each other and differ more between individuals than among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c3b231fe5fc3c5e4d769a947ae8893
https://pubmed.ncbi.nlm.nih.gov/15289471
https://pubmed.ncbi.nlm.nih.gov/15289471
Publikováno v:
Nature genetics. 22(1)
DNA sequence variation has become a major source of insight regarding the origin and history of our species as well as an important tool for the identification of allelic variants associated with disease. Comparative sequencing of DNA has to date foc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18d25f771686281128ee042a1a21f63
https://pubmed.ncbi.nlm.nih.gov/10319866
https://pubmed.ncbi.nlm.nih.gov/10319866
Autor:
Florian Heissig, Philipp Khaitovich, Wolfgang Enard, Svante Pääbo, Jarosław Bryk, Johannes Krause
Publikováno v:
Genome Biology. 6:R57
Background: It has long been argued that changes in gene expression may provide an additional and crucial perspective on the evolutionary differences between humans and chimpanzees. To investigate how often expression differences seen in tissues are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a1af2a6b14edcd4eaa1a0b66ac60771
https://doi.org/10.1186/gb-2005-6-7-r57
https://doi.org/10.1186/gb-2005-6-7-r57