Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Florian Hamberger"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Myofibroblasts are the source of extracellular matrix protein during liver fibrogenesis. Fibroblasts, hepatic stellate cells (HSCs) and vascular smooth muscle cells are mesenchymal subpopulations in the liver that are characterized by the ex
Externí odkaz:
https://doaj.org/article/70bd37ec843e480e86c8b3c36ed99e07
Autor:
Florian Hamberger, Ekaterina Legchenko, Philippe Chouvarine, Young Seon Mederacke, Richard Taubert, Martin Meier, Danny Jonigk, Georg Hansmann, Ingmar Mederacke
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Hepatic congestion occurs in patients with right heart failure and can ultimately lead to liver fibrosis or cardiac cirrhosis. Elevated pulmonary arterial pressure is found in patients with hepatic congestion. However, whether pulmonary arterial hype
Externí odkaz:
https://doaj.org/article/b982d252f13047849d7bfa4ae9c63168
Autor:
Ingmar Mederacke, Aveline Filliol, Silvia Affo, Ajay Nair, Celine Hernandez, Qiuyan Sun, Florian Hamberger, Francesco Brundu, Yu Chen, Aashreya Ravichandra, Peter Huebener, Helena Anke, Hongxue Shi, Raquel A. Martínez García de la Torre, James R. Smith, Neil C. Henderson, Florian W. R. Vondran, Carla V. Rothlin, Heike Baehre, Ira Tabas, Pau Sancho-Bru, Robert F. Schwabe
Publikováno v:
Sci Transl Med
Fibrosis contributes to ~45% of deaths in western countries. In chronic liver disease, fibrosis is a major factor determining outcomes, but efficient antifibrotic therapies are lacking. Although platelet-derived growth factor and transforming growth
Autor:
Nicholas Arpaia, Florian Hamberger, Raghu Kalluri, Ekihiro Seki, Thomas Savage, Di Zhu, Likang Chin, Ingmar Mederacke, Ajay Nair, Rebecca G. Wells, Maximilian Miller, Naita Maren Wirsik, Silvia Affò, Robert F. Schwabe, Aveline Filliol, Thomas Schmidt, Ben Z. Stanger, Matthias Mack, Kenneth P. Olive, Aashreya Ravichandra, Sonakshi Bhattacharjee, Peter A. Sims, Adam Mehal, Deqi Yin
Publikováno v:
J Clin Invest
The Journal of clinical investigation, vol 131, iss 11
The Journal of clinical investigation, vol 131, iss 11
Cancer-associated fibroblasts (CAF) may exert tumor-promoting and tumor-suppressive functions, but the mechanisms underlying these opposing effects remain elusive. Here, we sought to understand these potentially opposing functions by interrogating fu