Image-based consensus molecular subtyping in rectal cancer biopsies and response to neoadjuvant chemoradiotherapy

Autor: Maxime W. Lafarge, Enric Domingo, Korsuk Sirinukunwattana, Ruby Wood, Leslie Samuel, Graeme Murray, Susan D. Richman, Andrew Blake, David Sebag-Montefiore, Simon Gollins, Eckhard Klieser, Daniel Neureiter, Florian Huemer, Richard Greil, Philip Dunne, Philip Quirke, Lukas Weiss, Jens Rittscher, Tim Maughan, Viktor H. Koelzer

Publikováno v: npj Precision Oncology, Vol 8, Iss 1, Pp 1-11 (2024)

Abstract The development of deep learning (DL) models to predict the consensus molecular subtypes (CMS) from histopathology images (imCMS) is a promising and cost-effective strategy to support patient stratification. Here, we investigate whether imCM

Externí odkaz: https://doaj.org/article/069ba3e2373e479787af9c5a62731f11

Comparison of gemcitabine plus oxaliplatin versus gemcitabine plus nab‐paclitaxel as first‐line chemotherapy for advanced pancreatic adenocarcinoma: A single‐center retrospective analysis

Autor: Konstantin Schlick, Antonia Gantschnigg, Alexander Seymer, Florian Huemer, Richard Greil, Lukas Weiss

Publikováno v: Cancer Medicine, Vol 12, Iss 16, Pp 16997-17004 (2023)

Abstract Background Pancreatic cancer is mostly diagnosed in an advanced stage and treated with systemic therapy with palliative intent. Nowadays, the doublet chemotherapy of Gemcitabine and nab‐paclitaxel (Gem‐Nab) is one of the most frequently

Externí odkaz: https://doaj.org/article/b9a49e1c5b3e43409a6abf40578766f3

Management of metastatic colorectal cancer in patients ≥70 years - a single center experience

Autor: Florian Huemer, Celine Dunkl, Gabriel Rinnerthaler, Konstantin Schlick, Ronald Heregger, Klaus Emmanuel, Daniel Neureiter, Eckhard Klieser, Michael Deutschmann, Falk Roeder, Richard Greil, Lukas Weiss

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

BackgroundAge-standardized mortality rates for metastatic colorectal cancer (mCRC) are highest among elderly patients. In current clinical guidelines, treatment recommendations for this patient population are based on a limited number of clinical tri

Externí odkaz: https://doaj.org/article/720d9644af5b483b82a00212c0f67223

Selective growth of tensily strained Si1−yCy films on patterned Si substrates

Autor: D. Bensahel, Olivier Kermarrec, Alain Claverie, Martin Hÿtch, Florent Houdellier, Aomar Halimaoui, A. Gouyé, Yves Campidelli, Florian Hüe

Publikováno v: Materials Science in Semiconductor Processing
Materials Science in Semiconductor Processing, Elsevier, 2009, 12 (1-2), pp.34-39. ⟨10.1016/j.mssp.2009.07.006⟩
Materials Science in Semiconductor Processing, 2009, 12 (1-2), pp.34-39. ⟨10.1016/j.mssp.2009.07.006⟩

International audience; Advanced structures with poly-Si gates, Si3N4 spacers, and shallow trench isolation (STI) areas were used for elaborating the selective growth of Si1−yCy films into recessed source and drain (S/D).Selective Si1−yCy films w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c56295d420a5bc7980830c0490ea1a9
https://doi.org/10.1016/j.mssp.2009.07.006

Checkpoint inhibitors in metastatic gastric and GEJ cancer: a multi-institutional retrospective analysis of real-world data in a Western cohort

Autor: Verena Schlintl, Florian Huemer, Gabriel Rinnerthaler, Thomas Melchardt, Thomas Winder, Patrick Reimann, Jakob Riedl, Arno Amann, Wolfgang Eisterer, Franz Romeder, Gudrun Piringer, Aysegül Ilhan-Mutlu, Ewald Wöll, Richard Greil, Lukas Weiss

Publikováno v: BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)

Abstract Background Safety and efficacy of immune checkpoint inhibitors in advanced gastric or gastroesophageal junction (GEJ) cancer could be demonstrated in predominantly Asian cohorts, whereas data in Western patients outside of clinical trials ar

Externí odkaz: https://doaj.org/article/4eb806de63a04d64920beb1c085feb6d