Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Florian Greten"'
Autor:
Lydia Brandl, Yina Zhang, Nina Kirstein, Andrea Sendelhofert, Sophie Luise Boos, Peter Jung, Florian Greten, Roland Rad, Antje Menssen
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 10, Pp 974-988 (2019)
We recently described a positive feedback loop connecting c-MYC, NAMPT, DBC1 and SIRT1 that contributes to unrestricted cancer cell proliferation. Here we determine the relevance of the loop for serrated route intestinal tumorigenesis using genetical
Externí odkaz:
https://doaj.org/article/a992b9c5890340798b3dd2e59ec1e28e
Publikováno v:
Clinical Cancer Research. 29:1009-1016
Tumor-associated inflammation (TAI) is a feature of essentially all cancers and can confer both tumor-promoting and -suppressive functions. Cancer-associated fibroblasts (CAF) comprise one very heterogeneous cellular component of the tumor microenvir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeacdd856045983293b2044cf4f0c639
https://doi.org/10.1158/1078-0432.ccr-22-1031
https://doi.org/10.1158/1078-0432.ccr-22-1031
Autor:
Michaela Reissland, Oliver Hartmann, Saskia Tauch, Cristian Prieto-Garcia, Clemens Schulte, Daniel Solvie, Sinah Loebbert, Anne-Claire Jacomin, Marina Pesic, Jeroen Bugter, Christina Schülein-Völk, Carmina Fuss, Nikolett Pahor, Carsten Ade, Viktoria Buck, Michael Potente, Vivian Li, Gerti Beliu, Armin Wiegering, Eliya Bitman-Lotan, Tom Grossmann, Mathias Rosenfeldt, Martin Eilers, Hans Maric, Madelon Maurice, Florian Greten, Ivan Dikic, Amir Oryan, Peter Gallant, Markus Diefenbacher
The contribution of deubiquitylating enzymes to β-Catenin stabilisation in intestinal stem cells and colorectal cancer (CRC) is poorly understood. Here, we report the deubiquitylase USP10 as an APC-truncation- specific enhancer of β-Catenin stabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cbc08d25e5786a9e89293d3727f74c9
https://doi.org/10.21203/rs.3.rs-2647009/v1
https://doi.org/10.21203/rs.3.rs-2647009/v1
Autor:
Michaela Reissland, Oliver Hartmann, Saskia Tauch, Cristian Prieto-Garcia, Clemens Schulte, Daniel Solvie, Sinah Loebbert, Anne-Claire Jacomin, Marina Pesic, Jeroen M. Bugter, Christina Schuelein-Voelk, Carmina T. Fuss, Nikolet Pahor, Carsten Ade, Viktoria Buck, Michael Potente, Vivian Li, Gerti Beliu, Armin Wiegering, Eliya Bitman-Lotan, Tom Grossmann, Mathias Rosenfeldt, Martin Eilers, Hans Maric, Madelon M. Maurice, Florian Greten, Ivan Dikič, Amir Orian, Peter Gallant, Markus E. Diefenbacher
SummaryThe contribution of deubiquitylating enzymes to β-Catenin stabilisation in intestinal stem cells and colorectal cancer (CRC) is poorly understood. Here, we report the deubiquitylase USP10 as an APC-truncation- specific enhancer of β-Catenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07cbccc13dc3cb445f4a5957beac5545
https://doi.org/10.1101/2023.02.10.527983
https://doi.org/10.1101/2023.02.10.527983
Autor:
Florian Greten, Dominic Denk
Publikováno v:
Trends in cancer. 8(11)
An inflammatory microenvironment, either conferred by an underlying chronic overt or smoldering inflammatory condition constitutes a prerequisite and fuel to essentially all cancers. The complex reciprocal interplay of different cell types in the tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9bcc843824effaf54abb935e6c1f49
https://pubmed.ncbi.nlm.nih.gov/35907753
https://pubmed.ncbi.nlm.nih.gov/35907753
Publikováno v:
Europe PubMed Central
We used a murine tumor progression model for the evaluation of potential proliferation markers using positron emission tomography (PET). 5-[(18)F]-2'-deoxyuridine ([(18)F]FdUrd) was synthesized with98% radiochemical purity and investigated in a pancr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b0fdc1961fdbb983496aa263354ced39
https://pubmed.ncbi.nlm.nih.gov/11358795
https://pubmed.ncbi.nlm.nih.gov/11358795