Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Florian Full"'
Autor:
André Riedl, Denisa Bojková, Jiang Tan, Ábris Jeney, Pia-Katharina Larsen, Csaba Jeney, Florian Full, Ulrich Kalinke, Zsolt Ruzsics
Publikováno v:
Vaccines, Vol 12, Iss 7, p 791 (2024)
We investigated the basic characteristics of a new murine cytomegalovirus (MCMV) vector platform. Using BAC technology, we engineered replication-competent recombinant MCMVs with deletions of up to 26% of the wild-type genome. To this end, we targete
Externí odkaz:
https://doaj.org/article/b6cb218b667647bd97c3fdadf8733325
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Pioneer factors are transcription factors sharing the fascinating ability to bind to compact chromatin and thereby alter its transcriptional fate. Most pioneer factors are known for their importance during embryonic development, for instance, in indu
Externí odkaz:
https://doaj.org/article/40365b5e628247319b7c09721be07faf
Dual signaling via interferon and DNA damage response elicits entrapment by giant PML nuclear bodies
Autor:
Myriam Scherer, Clarissa Read, Gregor Neusser, Christine Kranz, Anna K Kuderna, Regina Müller, Florian Full, Sonja Wörz, Anna Reichel, Eva-Maria Schilling, Paul Walther, Thomas Stamminger
Publikováno v:
eLife, Vol 11 (2022)
PML nuclear bodies (PML-NBs) are dynamic interchromosomal macromolecular complexes implicated in epigenetic regulation as well as antiviral defense. During herpesvirus infection, PML-NBs induce epigenetic silencing of viral genomes, however, this def
Externí odkaz:
https://doaj.org/article/5abc06876a5046b2832b9522fd4a19e5
Autor:
Martin Schütz, Regina Müller, Eileen Socher, Christina Wangen, Florian Full, Emanuel Wyler, Diana Wong, Myriam Scherer, Thomas Stamminger, Sunwen Chou, William D. Rawlinson, Stuart T. Hamilton, Heinrich Sticht, Manfred Marschall
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11814 (2022)
The complex host interaction network of human cytomegalovirus (HCMV) involves the regulatory protein kinase pUL97, which represents a viral cyclin-dependent kinase (CDK) ortholog. pUL97 interacts with the three human cyclin types T1, H, and B1, where
Externí odkaz:
https://doaj.org/article/1e8fe2e70fcc4f7a8d7709274b08ee92
Autor:
Han Xiao, Emanuel Wyler, Miha Milek, Bastian Grewe, Philipp Kirchner, Arif Ekici, Ana Beatriz Oliveira Villela Silva, Doris Jungnickl, Florian Full, Marco Thomas, Markus Landthaler, Armin Ensser, Klaus Überla
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
To regulate its complex splicing pattern, HIV-1 uses the adaptor protein Rev to shuttle unspliced or partially spliced mRNA from the nucleus to the cytoplasm. In the absence of Rev, these RNAs are retained in the nucleus, but it is unclear why.
Externí odkaz:
https://doaj.org/article/024fe1f1a6964e11a3329f44d73767b6
Publikováno v:
Viruses, Vol 9, Iss 10, p 308 (2017)
Gammaherpesviruses like Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV) subvert the ubiquitin proteasome system for their own benefit in order to facilitate viral gene expression and replication. In particular, viral teg
Externí odkaz:
https://doaj.org/article/5361649b5b2448c4800daf4b09b402aa
Autor:
Florian Full, Doris Jungnickl, Nina Reuter, Elke Bogner, Kevin Brulois, Brigitte Scholz, Michael Stürzl, Jinjong Myoung, Jae U Jung, Thomas Stamminger, Armin Ensser
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1, p e1003863 (2014)
Nuclear domain 10 (ND10) components are restriction factors that inhibit herpesviral replication. Effector proteins of different herpesviruses can antagonize this restriction by a variety of strategies, including degradation or relocalization of ND10
Externí odkaz:
https://doaj.org/article/a4bd896fac714703b6d4ee7d93806646
Autor:
Manfred Lehner, Gabriel Götz, Julia Proff, Niels Schaft, Jan Dörrie, Florian Full, Armin Ensser, Yves A Muller, Adelheid Cerwenka, Hinrich Abken, Ornella Parolini, Peter F Ambros, Heinrich Kovar, Wolfgang Holter
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31210 (2012)
We explored the possibility to target Ewing's sarcoma family of tumors (ESFT) by redirecting T cells. To this aim, we considered NKG2D-ligands (NKG2D-Ls) as possible target antigens. Detailed analysis of the expression of MICA, MICB, ULBP-1, -2, and
Externí odkaz:
https://doaj.org/article/fe1b7ffa73194d2fa23042d04da80b5d
Autor:
Myriam Scherer, Clarissa Read, Gregor Neusser, Christine Kranz, Anna K Kuderna, Regina Müller, Florian Full, Sonja Wörz, Anna Reichel, Eva-Maria Schilling, Paul Walther, Thomas Stamminger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b74a81792794480871e33c278777753
https://doi.org/10.7554/elife.73006.sa2
https://doi.org/10.7554/elife.73006.sa2
Dual signaling via interferon and DNA damage response elicits entrapment by giant PML nuclear bodies
Autor:
Clarissa Read, Eva-Maria Schilling, Paul Walther, Anna Reichel, Christine Kranz, Regina Müller, Myriam Scherer, Florian Full, S. Woerz, Thomas Stamminger, Gregor Neusser
PML nuclear bodies (PML-NBs) are dynamic interchromosomal macromolecular complexes implicated in epigenetic regulation as well as antiviral defense. During herpesvirus infection, PML-NBs induce epigenetic silencing of viral genomes, however, this def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::031e51f331c1ba0d17f4708b3e006671
https://doi.org/10.1101/2021.08.24.457524
https://doi.org/10.1101/2021.08.24.457524