Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Florian David"'
Autor:
Jan Zrimec, Xiaozhi Fu, Azam Sheikh Muhammad, Christos Skrekas, Vykintas Jauniskis, Nora K. Speicher, Christoph S. Börlin, Vilhelm Verendel, Morteza Haghir Chehreghani, Devdatt Dubhashi, Verena Siewers, Florian David, Jens Nielsen, Aleksej Zelezniak
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Design of de novo synthetic regulatory DNA is a promising avenue to control gene expression in biotechnology and medicine. Here the authors present EspressionGAN, a generative adversarial network that uses genomic and transcriptomic data to generate
Externí odkaz:
https://doaj.org/article/bb9aa1851b914f7090a2adb235e06f6d
Autor:
Anne-Claire Godet, Emilie Roussel, Florian David, Fransky Hantelys, Florent Morfoisse, Joffrey Alves, Françoise Pujol, Isabelle Ader, Edouard Bertrand, Odile Burlet-Schiltz, Carine Froment, Anthony K Henras, Patrice Vitali, Eric Lacazette, Florence Tatin, Barbara Garmy-Susini, Anne-Catherine Prats
Publikováno v:
eLife, Vol 11 (2022)
Internal ribosome entry sites (IRESs) drive translation initiation during stress. In response to hypoxia, (lymph)angiogenic factors responsible for tissue revascularization in ischemic diseases are induced by the IRES-dependent mechanism. Here, we se
Externí odkaz:
https://doaj.org/article/e52ee2c8435149d8943b2cb22a61cd57
Autor:
Maximilian Otto, Paulo Gonçalves Teixeira, Maria Isabel Vizcaino, Florian David, Verena Siewers
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-17 (2019)
Abstract Background The sesquiterpenoid abscisic acid (ABA) is mostly known for regulating developmental processes and abiotic stress responses in higher plants. Recent studies show that ABA also exhibits a variety of pharmacological activities. Affo
Externí odkaz:
https://doaj.org/article/1662be6e9e4540448db4114cba6c192e
Autor:
Leonie Wenning, Christer S. Ejsing, Florian David, Richard R. Sprenger, Jens Nielsen, Verena Siewers
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-17 (2019)
Abstract Background Fatty acids (FAs) with a chain length of more than 18 carbon atoms (> C18) are interesting for the production of specialty compounds derived from these FAs. These compounds include free FAs, like erucic acid (C22:1-Δ13), primary
Externí odkaz:
https://doaj.org/article/a71f3556e5894ca68be272c35cba4243
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0239882 (2020)
Alkane-based biofuels are desirable to produce at a commercial scale as these have properties similar to current petroleum-derived transportation fuels. Rationally engineering microorganisms to produce a desirable compound, such as alkanes, is, howev
Externí odkaz:
https://doaj.org/article/234e8c092c4d4836987719c2cc52a18d
Autor:
Fransky Hantelys, Anne-Claire Godet, Florian David, Florence Tatin, Edith Renaud-Gabardos, Françoise Pujol, Leila H Diallo, Isabelle Ader, Laetitia Ligat, Anthony K Henras, Yasufumi Sato, Angelo Parini, Eric Lacazette, Barbara Garmy-Susini, Anne-Catherine Prats
Publikováno v:
eLife, Vol 8 (2019)
Hypoxia, a major inducer of angiogenesis, triggers major changes in gene expression at the transcriptional level. Furthermore, under hypoxia, global protein synthesis is blocked while internal ribosome entry sites (IRES) allow specific mRNAs to be tr
Externí odkaz:
https://doaj.org/article/74e2fd9e102344969fe2b18398f709b8
Autor:
Raphael Ferreira, Paulo Gonçalves Teixeira, Michael Gossing, Florian David, Verena Siewers, Jens Nielsen
Publikováno v:
Metabolic Engineering Communications, Vol 6, Iss , Pp 22-27 (2018)
Triacylglycerols (TAGs) are valuable versatile compounds that can be used as metabolites for nutrition and health, as well as feedstocks for biofuel production. Although Saccharomyces cerevisiae is the favored microbial cell factory for industrial pr
Externí odkaz:
https://doaj.org/article/c5a79a1d9c6842708848dbc949e60b35
Autor:
Tao Yu, Yongjin J. Zhou, Leonie Wenning, Quanli Liu, Anastasia Krivoruchko, Verena Siewers, Jens Nielsen, Florian David
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Production of chemicals by microbial fermentation is an economical alternative to chemical synthesis. Here the authors re-engineer the yeastS. cerevisiaeto produce the very long chain fatty alcohol docosanol by expressing a heterologous Mycobacteria
Externí odkaz:
https://doaj.org/article/36f3a67ebbcd46798748b17bc28b8b18
Autor:
Tao Yu, Yongjin J. Zhou, Leonie Wenning, Quanli Liu, Anastasia Krivoruchko, Verena Siewers, Jens Nielsen, Florian David
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications 8: Article number: 15587 (2017); Published: 26 May 2017, Updated: 13 July 2018 In the originally published version of this Article, financial support was not fully acknowledged. The PDF and HTML versions of the Article have now
Externí odkaz:
https://doaj.org/article/b7bc770f7e634861b917495da7c010c1
Autor:
Scott, Taylor E., Boccarossa, Tim, Florian, David, Fischer, Melissa A., Peck, Sun H., Savona, Michael R., Pingen, Georg, Guelcher, Scott A.
Publikováno v:
In Heliyon 15 August 2024 10(15)