Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Florian D. Hastert"'
Autor:
Christin Schmidt, Julia Gerbeth, Christine von Rhein, Florian D. Hastert, Barbara S. Schnierle
Publikováno v:
Viruses, Vol 16, Iss 7, p 1033 (2024)
A recombinant Ross River virus (RRV) that contains the fluorescent protein mCherry fused to the non-structural protein 3 (nsP3) was constructed, which allowed real-time imaging of viral replication. RRV-mCherry contained either the natural opal stop
Externí odkaz:
https://doaj.org/article/3f62d28bbe054e10ada35ba97eed5150
Autor:
María Arroyo, Florian D. Hastert, Andreas Zhadan, Florian Schelter, Susanne Zimbelmann, Cathia Rausch, Anne K. Ludwig, Thomas Carell, M. Cristina Cardoso
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-28 (2022)
A short isoform of the Tet1 enzyme (Tet1s) that oxidizes the DNA 5-methylcytosine (5mC) mark is overexpressed in tumors. Here the authors show Tet1s, but not full length Tet1, changes localization over the cell cycle upon ubiquitination and Uhrf1 int
Externí odkaz:
https://doaj.org/article/4bd2bce040994572835707652c0ebd76
Autor:
María Arroyo, Florian D. Hastert, Andreas Zhadan, Florian Schelter, Susanne Zimbelmann, Cathia Rausch, Anne K. Ludwig, Thomas Carell, M. Cristina Cardoso
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/f3d86993de65494b9a523388754a4850
Autor:
Christin Schmidt, Florian D. Hastert, Julia Gerbeth, Tim Beissert, Ugur Sahin, Mario Perkovic, Barbara S. Schnierle
Publikováno v:
Vaccines, Vol 10, Iss 9, p 1374 (2022)
Alphaviruses such as the human pathogenic chikungunya virus (CHIKV) and Ross River virus (RRV) can cause explosive outbreaks raising public health concerns. However, no vaccine or specific antiviral treatment is yet available. We recently established
Externí odkaz:
https://doaj.org/article/1248d33fb49a4a7cb963048bb93ccafe
Autor:
Florian D. Hastert, Sascha Hein, Christine von Rhein, Nuka Ivalu Benz, Younes Husria, Doris Oberle, Thorsten J. Maier, Eberhard Hildt, Barbara S. Schnierle
Publikováno v:
Vaccines, Vol 10, Iss 5, p 794 (2022)
The SARS-CoV-2 variant Omicron has spread world-wide and is responsible for rapid increases in infections, including in populations with high vaccination rates. Here, we analysed in the sera of vaccinated individuals the antibody binding to the recep
Externí odkaz:
https://doaj.org/article/cb303763eb034c6cbff83ad987d871b3
Autor:
Florian D. Hastert, Lisa Henss, Christine von Rhein, Julia Gerbeth, Imke Wieters, Frauke Borgans, Yascha Khodamoradi, Kai Zacharowski, Gernot Rohde, Maria J.G.T. Vehreschild, Barbara S. Schnierle
Publikováno v:
Viruses, Vol 14, Iss 5, p 882 (2022)
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic has now been continuing for more than two years. The infection causes COVID-19, a disease of the respiratory and cardiovascular system of variable severity. Here, the humoral i
Externí odkaz:
https://doaj.org/article/3f798f13f58343bd8df7d2b98e4b6083
Autor:
Marie-Luise Herrlein, Sascha Hein, Tobias Zahn, Ines Mhedhbi, Jan Raupach, Younes Husria, Nuka Ivalu Benz, Jonathan Eisert, Daniela Bender, Vanessa Haberger, Florian D. Hastert, Lisa Henss, Barbara S. Schnierle, Julia C. Stingl, Michael Dreher, Eberhard Hildt
Publikováno v:
Viruses, Vol 14, Iss 2, p 410 (2022)
In light of an increasing number of vaccinated and convalescent individuals, there is a major need for the development of robust methods for the quantification of neutralizing antibodies; although, a defined correlate of protection is still missing.
Externí odkaz:
https://doaj.org/article/6308a186ab2d442dac3f373702a5e91f
Autor:
Malini Rajan, Oliver Mortusewicz, Ulrich Rothbauer, Florian D. Hastert, Katrin Schmidthals, Alexander Rapp, Heinrich Leonhardt, M. Cristina Cardoso
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 779-788 (2015)
Post‐translational modifications are difficult to visualize in living cells and are conveniently analyzed using antibodies. Single‐chain antibody fragments derived from alpacas and called nanobodies can be expressed and bind to the target antigen
Externí odkaz:
https://doaj.org/article/ba209d7079364f15884bd6637543f620
Autor:
Bingqian Qu, Csaba Miskey, André Gömer, Dylan Potmus, Maximillian Nocke, Robin D.V. Kleinert, Tabitha K. Itotia, Lara Valder, Janice Brückmann, Sebastian Höck, Florian D. Hastert, Christine von Rhein, Christoph Schürmann, Aileen Ebenig, Marek Widera, Sandra Ciesek, Stephanie Pfaender, Zoltán Ivics, Barbara S. Schnierle, Alexander W. Tarr, Christine Goffinet, Michael D. Mühlebach, Daniel Todt, Richard J.P. Brown
SARS-CoV-2 entry is promoted by both cell-surface TMPRSS2 and endolysosomal cathepsins. To investigate the impact of differentially routed virions on host and viral processes, lung epithelial cells expressing distinct combinations of entry factors we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3754bd3ba15fb507050b9e65e13df0a8
https://doi.org/10.1101/2022.08.05.502936
https://doi.org/10.1101/2022.08.05.502936
Autor:
Stefan Canzar, Vigo Heissmeyer, Nicholas B. Angstman, Mark Helm, Aloys Schepers, Franziska Weichmann, Kaouthar Slama, Regina Feederle, Julian König, Robert Hett, Gunter Meister, Florian D. Hastert, M. Cristina Cardoso, Taku Ito-Kureha, Stefan Hüttelmaier, Andrew Flatley, Christoph Dieterich
Publikováno v:
RNA
Chemical modifications are found on almost all RNAs and affect their coding and noncoding functions. The identification of m6A on mRNA and its important role in gene regulation stimulated the field to investigate whether additional modifications are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774ba88d110b3d78cd7df016f58b05c2
https://doi.org/10.1261/rna.076026.120
https://doi.org/10.1261/rna.076026.120