Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Florian Bochen"'
Publikováno v:
Methods and Protocols, Vol 6, Iss 5, p 94 (2023)
Although 2D in vitro cancer cell cultures have been used for decades as a first line-of-research tool to investigate antitumoral drugs and treatments, their use presents many drawbacks, including the poor resemblance of such cultures to the character
Externí odkaz:
https://doaj.org/article/fe220a9224e64d7497afd99404574948
Autor:
Irida Papapostolou, Daniela Ross-Kaschitza, Florian Bochen, Christine Peinelt, Maria Constanza Maldifassi
Publikováno v:
Cells, Vol 12, Iss 15, p 2000 (2023)
Nicotine in tobacco is known to induce tumor-promoting effects and cause chemotherapy resistance through the activation of nicotinic acetylcholine receptors (nAChRs). Many studies have associated the α5 nicotinic receptor subunit (α5), and a specif
Externí odkaz:
https://doaj.org/article/a830cd96edcf4a45922be0ddd5dca604
Autor:
Barbara Preti, Jean-Sébastien Rougier, Irida Papapostolou, Florian Bochen, Christian E. Gerber, Hugues Abriel, Martin Lochner, Christine Peinelt
Publikováno v:
CHIMIA, Vol 76, Iss 12 (2022)
The transient receptor potential melastatin 4 (TRPM4) ion channel is ubiquitously expressed. Dysregulation and/or functional mutations of TRPM4 lead to several diseases. Within our studies, we screened for TRPM4 inhibitors and identified small molecu
Externí odkaz:
https://doaj.org/article/344d922443754d068dbe864dca6661ba
Autor:
Sandrina Körner, Tillman Pick, Florian Bochen, Silke Wemmert, Christina Körbel, Michael D. Menger, Adolfo Cavalié, Jan-Philipp Kühn, Bernhard Schick, Maximilian Linxweiler
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Various cancer types including head and neck squamous cell carcinomas (HNSCC) show a frequent amplification of chromosomal region 3q26 that encodes, among others, for the SEC62 gene. Located in the ER membrane, this translocation protein is known to
Externí odkaz:
https://doaj.org/article/0426341b74634c209f3abae9d889c5c9
Autor:
Maximilian Linxweiler, Lukas Pillong, Dragan Kopanja, Jan P. Kühn, Stefan Wagenpfeil, Julia C. Radosa, Jingming Wang, Luc G. T. Morris, Basel Al Kadah, Florian Bochen, Sandrina Körner, Bernhard Schick
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 5, Iss 4, Pp 621-629 (2020)
Abstract Objective Endoscopic sinus surgery represents the gold standard for surgical treatment of chronic sinus diseases. Thereby, navigation systems can be of distinct use. In our study, we tested the recently developed KARL STORZ NAV1 SinusTracker
Externí odkaz:
https://doaj.org/article/22728133fa86494aa5607843a9e4bf1c
Autor:
Mark Sicking, Sven Lang, Florian Bochen, Andreas Roos, Joost P. H. Drenth, Muhammad Zakaria, Richard Zimmermann, Maximilian Linxweiler
Publikováno v:
Cells, Vol 10, Iss 5, p 1036 (2021)
The rough endoplasmic reticulum (ER) of nucleated human cells has crucial functions in protein biogenesis, calcium (Ca2+) homeostasis, and signal transduction. Among the roughly one hundred components, which are involved in protein import and protein
Externí odkaz:
https://doaj.org/article/b70b2c616970485280a521baca4866e0
Autor:
Florian Bochen, Benedikt Balensiefer, Sandrina Körner, Jörg Thomas Bittenbring, Frank Neumann, Armand Koch, Klaus Bumm, Anke Marx, Silke Wemmert, Georgios Papaspyrou, David Zuschlag, Jan Philipp Kühn, Basel Al Kadah, Bernhard Schick, Maximilian Linxweiler
Publikováno v:
OncoImmunology, Vol 7, Iss 9 (2018)
Vitamin D deficiency is frequently observed in human cancer patients and a prognostic relevance could be shown for some entities. Additionally, it is known that vitamin D can stimulate the patients’ antitumor immunity. However, valid epidemiologica
Externí odkaz:
https://doaj.org/article/10485d48500246e78e2de334292c6b83
Autor:
Sandrina Körner, Tillman Pick, Florian Bochen, Silke Wemmert, Christina Körbel, Michael D. Menger, Adolfo Cavalié, Jan-Philipp Kühn, Bernhard Schick, Maximilian Linxweiler
Various cancer types including head and neck squamous cell carcinomas (HNSCC) show a frequent amplification of chromosomal region 3q26 that encodes, among others, for the SEC62 gene. Located in the ER membrane, this translocation protein is known to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd83d6ae467fc0f30e5019fdca25d79
Autor:
Jan Philipp Kühn, Florian Bochen, Sandrina Körner, Bernhard Schick, Mathias Wagner, Sigrun Smola, Barbara Berkó-Göttel, Luc G.T. Morris, Jingming Wang, Alessandro Bozzato, Maximilian Linxweiler
Publikováno v:
The International journal of biological markers. 37(3)
Introduction Head and neck squamous cell carcinomas (HNSCCs) are cancers with generally poor prognosis. Outcomes have not improved in decades, with more than half of the patients presenting with lymph node metastases at the time of diagnosis. A uniqu
Autor:
Meike Vorschel, Jan-Philipp Kühn, Florian Bochen, Sandrina Körner, Silke Wemmert, Mathias Wagner, Bernhard Schick, Maximilian Linxweiler
Publikováno v:
Abstract- und Posterband - 93. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn Interface - Fokus Mensch im Zeitalter der technisierten Medizin.