Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Florian Barthel"'
In this work, we propose a method that enforces explicit control over various attributes during the image generation process in a generative adversarial net. We propose a semi-supervised learning procedure that allows us to use a quantized approximat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208e379ae6c406b6aa332187dbb3c00b
https://opus.bibliothek.uni-augsburg.de/opus4/files/99370/s42979-022-01462-w.pdf
https://opus.bibliothek.uni-augsburg.de/opus4/files/99370/s42979-022-01462-w.pdf
Autor:
Philippe Deruelle, Florian Barthel, Fanny De Marcillac, Florence Vibert, Lise Lecointre, Mathilda Kretz, Vincent Thuet
Publikováno v:
European Journal of Obstetrics & Gynecology and Reproductive Biology
European Journal of Obstetrics, Gynecology, and Reproductive Biology
European Journal of Obstetrics, Gynecology, and Reproductive Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c276eee16d4bf6bf09dff6a80c7be62
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/99e23d6deecf4d4a969b4fc12d2ded22
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Duchenne Muscular Dystrophy (DMD)’s complex multi-system pathophysiology, coupled with the cost-prohibitive logistics of multi-year drug screening and follow-up, has hampered the pursuit of new therapeutic approaches. Here we conducted a systematic
Externí odkaz:
https://doaj.org/article/f5e601e97c20499db387a24adf0cb3d4
Autor:
Deirdre D. Scripture-Adams, Kevin N. Chesmore, Florian Barthélémy, Richard T. Wang, Shirley Nieves-Rodriguez, Derek W. Wang, Ekaterina I. Mokhonova, Emilie D. Douine, Jijun Wan, Isaiah Little, Laura N. Rabichow, Stanley F. Nelson, M. Carrie Miceli
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
A method to isolate and sequence individual nuclei from human and mouse muscle biopsies provides further insight into the mechanisms of dystrophin loss and repair, in the context of Duchenne muscular dystrophy.
Externí odkaz:
https://doaj.org/article/52c54e56cb454536bdffeb1964579512
Autor:
Shirley Nieves-Rodriguez, Florian Barthélémy, Jeremy D. Woods, Emilie D. Douine, Richard T. Wang, Deirdre D. Scripture-Adams, Kevin N. Chesmore, Francesca Galasso, M. Carrie Miceli, Stanley F. Nelson
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Muscle damage and fibro-fatty replacement of skeletal muscles is a main pathologic feature of Duchenne muscular dystrophy (DMD) with more proximal muscles affected earlier and more distal affected later in the disease course, suggesting that differen
Externí odkaz:
https://doaj.org/article/9a27a0c852384f55bc7769d063aa2045
Autor:
David P. Bishop, Mika T. Westerhausen, Florian Barthelemy, Thomas Lockwood, Nerida Cole, Elizabeth M. Gibbs, Rachelle H. Crosbie, Stanley F. Nelson, M. Carrie Miceli, Philip A. Doble, Jonathan Wanagat
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Emerging and promising therapeutic interventions for Duchenne muscular dystrophy (DMD) are confounded by the challenges of quantifying dystrophin. Current approaches have poor precision, require large amounts of tissue, and are difficult to
Externí odkaz:
https://doaj.org/article/32e5306aad14480599e6b5ea950d9a34
Autor:
Florian Barthélémy, Jeffrey W. Santoso, Laura Rabichow, Rongcheng Jin, Isaiah Little, Stanley F. Nelson, Megan L. McCain, M. Carrie Miceli
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
In vitro models of patient-derived muscle allow for more efficient development of genetic medicines for the muscular dystrophies, which often present mutation-specific pathologies. One popular strategy to generate patient-specific myotubes involves r
Externí odkaz:
https://doaj.org/article/73fc79b089c845ef877ae95d996f78e5
Autor:
Florian Barthélémy, Richard T. Wang, Christopher Hsu, Emilie D. Douine, Eugene E. Marcantonio, Stanley F. Nelson, M. Carrie Miceli
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss , Pp 580-589 (2019)
Systemic delivery of antisense oligonucleotides (AO) for DMD exon skipping has proven effective for reframing DMD mRNA, rescuing dystrophin expression, and slowing disease progression in animal models. In humans with Duchenne muscular dystrophy treat
Externí odkaz:
https://doaj.org/article/226d7e2db31d4f8d878ca8392b88261f