Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Florian B. Heiss"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
RNA polymerase (Pol) I transcribes the ribosomal RNA precursor in eukaryotes. Here, the authors present three cryo-EM structure of S. pombe Pol I in different functional states among them a dimer structure and discuss conserved and organism-specific
Externí odkaz:
https://doaj.org/article/53e86eb9a38e4e3ca3cb74b179cc8926
Autor:
Kevin Kramm, Tim Schröder, Jerome Gouge, Andrés Manuel Vera, Kapil Gupta, Florian B. Heiss, Tim Liedl, Christoph Engel, Imre Berger, Alessandro Vannini, Philip Tinnefeld, Dina Grohmann
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
TATA-binding protein (TBP) and a transcription factor (TF) IIB-like factor are important constituents of all eukaryotic initiation complexes. Here, the authors use a DNA origami-based force clamp to investigate the assembly dynamics of human initiati
Externí odkaz:
https://doaj.org/article/6c52a4bb73744eafa2b7a2b2daca7321
Autor:
Michael Pilsl, Florian B. Heiss, Gisela Pöll, Mona Höcherl, Philipp Milkereit, Christoph Engel
Publikováno v:
Methods Mol Biol
Ribosome Biogenesis ISBN: 9781071625002
Ribosome Biogenesis ISBN: 9781071625002
Recent technological progress revealed new prospects of high-resolution structure determination of macromolecular complexes using cryo-electron microscopy (cryo-EM). In the field of RNA polymerase (Pol) I research, a number of cryo-EM studies contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc22e404a313434c6acef0ad2966ba2
https://europepmc.org/articles/PMC9761500/
https://europepmc.org/articles/PMC9761500/
Autor:
Julia L. Daiß, Michael Pilsl, Kristina Straub, Andrea Bleckmann, Mona Höcherl, Florian B. Heiss, Guillermo Abascal-Palacios, Ewan Ramsay, Katarina Tlučková, Jean-Clement Mars, Astrid Bruckmann, Carrie Bernecky, Valérie Lamour, Konstantin Panov, Alessandro Vannini, Tom Moss, Christoph Engel
Transcription of the ribosomal RNA precursor by RNA polymerase (Pol) I is a major determinant of cellular growth and dysregulation is observed in many cancer types. Here, we present the purification of human Pol I from cells carrying a genomic GFP-fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4813cf94db26eeddb7ecca889d3df0c8
https://doi.org/10.1101/2021.12.22.473891
https://doi.org/10.1101/2021.12.22.473891
Publikováno v:
Nature Communications
RNA polymerase (Pol) I transcribes the ribosomal RNA precursor in all eukaryotes. The mechanisms ‘activation by cleft contraction’ and ‘hibernation by dimerization’ are unique to the regulation of this enzyme, but structure-function analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::050d3d694a6fff97e41ed53d55e6054a
https://pubmed.ncbi.nlm.nih.gov/33536435
https://pubmed.ncbi.nlm.nih.gov/33536435
Autor:
Andrés Manuel Vera, Philip Tinnefeld, Tim Schröder, Christoph Engel, Alessandro Vannini, Kevin Kramm, Dina Grohmann, Tim Liedl, Florian B. Heiss, Jerome Gouge
The TATA-binding protein (TBP) and a transcription factor (TF) IIB-like factor compound the fundamental core of all eukaryotic initiation complexes. The reason for the emergence and strict requirement of the additional intiation factor Bdp1, which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ce5b3c16683572e18c7d47b13dd865
https://doi.org/10.1101/775528
https://doi.org/10.1101/775528